SAR and in vivo evaluation of 4-aryl-2-aminoalkylpyrimidines as potent and selective Janus kinase 2 (JAK2) inhibitors
about
Selective JAK inhibitors.Design, synthesis, and evaluation of the anticancer activity of 2-amino-aryl-7-aryl-benzoxazole compounds.Inhibitor-based affinity probes for the investigation of JAK signaling pathways.Molecular dynamics and integrated pharmacophore-based identification of dual [Formula: see text] inhibitors.Ligand-based and e-pharmacophore modeling, 3D-QSAR and hierarchical virtual screening to identify dual inhibitors of spleen tyrosine kinase (Syk) and janus kinase 3 (JAK3).
P2860
SAR and in vivo evaluation of 4-aryl-2-aminoalkylpyrimidines as potent and selective Janus kinase 2 (JAK2) inhibitors
description
2012 nî lūn-bûn
@nan
2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
SAR and in vivo evaluation of ...... nus kinase 2 (JAK2) inhibitors
@ast
SAR and in vivo evaluation of ...... nus kinase 2 (JAK2) inhibitors
@en
SAR and in vivo evaluation of ...... nus kinase 2 (JAK2) inhibitors
@nl
type
label
SAR and in vivo evaluation of ...... nus kinase 2 (JAK2) inhibitors
@ast
SAR and in vivo evaluation of ...... nus kinase 2 (JAK2) inhibitors
@en
SAR and in vivo evaluation of ...... nus kinase 2 (JAK2) inhibitors
@nl
prefLabel
SAR and in vivo evaluation of ...... nus kinase 2 (JAK2) inhibitors
@ast
SAR and in vivo evaluation of ...... nus kinase 2 (JAK2) inhibitors
@en
SAR and in vivo evaluation of ...... nus kinase 2 (JAK2) inhibitors
@nl
P2093
P1476
SAR and in vivo evaluation of ...... nus kinase 2 (JAK2) inhibitors
@en
P2093
Adam A Galan
Arlyn Arcalas
Brian H Ridgway
Brian Kane
Byung Gyu Kim
Craig S Takeuchi
David S Brown
Elena S Koltun
Gary L Lewis
Grace Mann
P304
P356
10.1016/J.BMCL.2012.10.007
P407
P577
2012-12-15T00:00:00Z