Strategic use of conformational bias and structure based design to identify potent JAK3 inhibitors with improved selectivity against the JAK family and the kinome
about
Review: basics of drug development in rheumatologyAdvances in kinase inhibition: treating rheumatic diseases and beyond.Novel hinge-binding motifs for Janus kinase 3 inhibitors: a comprehensive structure-activity relationship study on tofacitinib bioisosteres.Highly selective Janus kinase 3 inhibitors based on a pyrrolo[2,3-d]pyrimidine scaffold: evaluation of WO2013085802.Molecular dynamics and integrated pharmacophore-based identification of dual [Formula: see text] inhibitors.Finding new scaffolds of JAK3 inhibitors in public database: 3D-QSAR models & shape-based screening.Ligand-based and e-pharmacophore modeling, 3D-QSAR and hierarchical virtual screening to identify dual inhibitors of spleen tyrosine kinase (Syk) and janus kinase 3 (JAK3).
P2860
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P2860
Strategic use of conformational bias and structure based design to identify potent JAK3 inhibitors with improved selectivity against the JAK family and the kinome
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2013 nî lūn-bûn
@nan
2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Strategic use of conformationa ...... the JAK family and the kinome
@ast
Strategic use of conformationa ...... the JAK family and the kinome
@en
Strategic use of conformationa ...... the JAK family and the kinome
@nl
type
label
Strategic use of conformationa ...... the JAK family and the kinome
@ast
Strategic use of conformationa ...... the JAK family and the kinome
@en
Strategic use of conformationa ...... the JAK family and the kinome
@nl
prefLabel
Strategic use of conformationa ...... the JAK family and the kinome
@ast
Strategic use of conformationa ...... the JAK family and the kinome
@en
Strategic use of conformationa ...... the JAK family and the kinome
@nl
P2093
P1476
Strategic use of conformationa ...... the JAK family and the kinome
@en
P2093
Allen Lovey
Calvin Yee
Douglas Roy
Javier DeVicente
Johannes C Hermann
John Menke
Linghao Niu
Michael Soth
Minh Diem Vu
P304
P356
10.1016/J.BMCL.2013.02.012
P407
P577
2013-05-01T00:00:00Z