Discovery of a series of novel 5H-pyrrolo[2,3-b]pyrazine-2-phenyl ethers, as potent JAK3 kinase inhibitors

Discovery of a series of novel 5H-pyrrolo[2,3-b]pyrazine-2-phenyl ethers, as potent JAK3 kinase inhibitors

Item
http://www.wikidata.org/entity/Q27684317
Advances in kinase inhibition: treating rheumatic diseases and beyond.Novel hinge-binding motifs for Janus kinase 3 inhibitors: a comprehensive structure-activity relationship study on tofacitinib bioisosteres.Pharmacophore and Virtual Screening of JAK3 inhibitors.The Specific Roles of JAK/STAT Signaling Pathway in Sepsis.Development of Selective Covalent Janus Kinase 3 Inhibitors.Highly selective Janus kinase 3 inhibitors based on a pyrrolo[2,3-d]pyrimidine scaffold: evaluation of WO2013085802.Molecular dynamics and integrated pharmacophore-based identification of dual [Formula: see text] inhibitors.Finding new scaffolds of JAK3 inhibitors in public database: 3D-QSAR models & shape-based screening.Ligand-based and e-pharmacophore modeling, 3D-QSAR and hierarchical virtual screening to identify dual inhibitors of spleen tyrosine kinase (Syk) and janus kinase 3 (JAK3).
P2860

Discovery of a series of novel 5H-pyrrolo[2,3-b]pyrazine-2-phenyl ethers, as potent JAK3 kinase inhibitors

Item
http://www.wikidata.org/entity/Q27684317
description
2013 nî lūn-bûn
@nan
2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Discovery of a series of novel ...... potent JAK3 kinase inhibitors
@ast
Discovery of a series of novel ...... potent JAK3 kinase inhibitors
@en
Discovery of a series of novel ...... potent JAK3 kinase inhibitors
@nl
type
label
Discovery of a series of novel ...... potent JAK3 kinase inhibitors
@ast
Discovery of a series of novel ...... potent JAK3 kinase inhibitors
@en
Discovery of a series of novel ...... potent JAK3 kinase inhibitors
@nl
prefLabel
Discovery of a series of novel ...... potent JAK3 kinase inhibitors
@ast
Discovery of a series of novel ...... potent JAK3 kinase inhibitors
@en
Discovery of a series of novel ...... potent JAK3 kinase inhibitors
@nl
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P356
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P5875
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P1433
P1476
Discovery of a series of novel ...... potent JAK3 kinase inhibitors
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P2093
P304
P31
P356
10.1016/J.BMCL.2013.03.015
P407
P433
P478
P50
P577
P5875
P698