about
Structural basis of AMPK regulation by small molecule activatorsAMP-activated protein kinase: a cellular energy sensor that comes in 12 flavoursIn silico design for adenosine monophosphate-activated protein kinase agonist from traditional chinese medicine for treatment of metabolic syndromes.Modulation of glucose metabolism by a natural compound from Chloranthus japonicus via activation of AMP-activated protein kinaseMechanism of action of compound-13: an α1-selective small molecule activator of AMPKTargeting AMPK: From Ancient Drugs to New Small-Molecule Activators.Structural basis of AMPK regulation by adenine nucleotides and glycogen.Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding.Architectural plasticity of AMPK revealed by electron microscopy and X-ray crystallographyThe Hsp70 homolog Ssb and the 14-3-3 protein Bmh1 jointly regulate transcription of glucose repressed genes in Saccharomyces cerevisiaeAMP-activated protein kinase: a key regulator of energy balance with many roles in human disease.AMPK--sensing energy while talking to other signaling pathways.Deconvoluting AMP-activated protein kinase (AMPK) adenine nucleotide binding and sensingActivation of AMP-activated protein kinase revealed by hydrogen/deuterium exchange mass spectrometry.Probing the enzyme kinetics, allosteric modulation and activation of α1- and α2-subunit-containing AMP-activated protein kinase (AMPK) heterotrimeric complexes by pharmacological and physiological activators.Adenosine Monophosphate-Activated Protein Kinase (AMPK) as a Diverse Therapeutic Target: A Computational Perspective.Phosphorylation of AMPK by upstream kinases is required for activity in mammalian cells.The yeast Hsp70 homolog Ssb: a chaperone for general de novo protein folding and a nanny for specific intrinsically disordered protein domains.Inhibition of AMP Kinase by the Protein Phosphatase 2A Heterotrimer, PP2APpp2r2d.Redox proteomics screening cellular factors associated with oxidative stress in hepatocarcinogenesis.Targeting of AMP-activated protein kinase: prospects for computer-aided drug design.Structural and biochemical insights into the allosteric activation mechanism of AMP-activated protein kinase.Structure and Regulation of AMPK.Targeting the energy guardian AMPK: another avenue for treating cardiomyopathy?AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance.Choreography of AMPK activation.AMP-activated protein kinase - not just an energy sensor.Coordinated regulation of AMPK activity by multiple elements in the α-subunit.Repurposing existing drugs for new AMPK activators as a strategy to extend lifespan: a computer-aided drug discovery study.2-[2-(4-(trifluoromethyl)phenylamino)thiazol-4-yl]acetic acid (Activator-3) is a potent activator of AMPK.
P2860
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P2860
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Conserved regulatory elements in AMPK
@ast
Conserved regulatory elements in AMPK
@en
Conserved regulatory elements in AMPK
@nl
type
label
Conserved regulatory elements in AMPK
@ast
Conserved regulatory elements in AMPK
@en
Conserved regulatory elements in AMPK
@nl
prefLabel
Conserved regulatory elements in AMPK
@ast
Conserved regulatory elements in AMPK
@en
Conserved regulatory elements in AMPK
@nl
P2093
P2860
P3181
P356
P1433
P1476
Conserved regulatory elements in AMPK
@en
P2093
Dietbert Neumann
Feng-Jiao Xin
Jia-Wei Wu
Jicheng Hu
Lu-Sha Cao
P2860
P2888
P3181
P356
10.1038/NATURE12189
P407
P577
2013-06-13T00:00:00Z
P5875
P6179
1035566944