Identification of a Small Molecule that Increases Hemoglobin Oxygen Affinity and Reduces SS Erythrocyte Sickling
about
Aryloxyalkanoic Acids as Non-Covalent Modifiers of the Allosteric Properties of HemoglobinKinetic assay shows that increasing red cell volume could be a treatment for sickle cell disease.Identification of a novel class of covalent modifiers of hemoglobin as potential antisickling agentsAllosteric Partial Inhibition of Monomeric Proteases. Sulfated Coumarins Induce Regulation, not just Inhibition, of Thrombin.Methemoglobin Formation and Characterization of Hemoglobin Adducts of Carcinogenic Aromatic Amines and Heterocyclic Aromatic Amines.New developments in anti-sickling agents: can drugs directly prevent the polymerization of sickle haemoglobin in vivo?Should modulation of p50 be a therapeutic target in the critically ill?Oxidative pathways in the sickle cell and beyond.Targeting βCys93 in hemoglobin S with an antisickling agent possessing dual allosteric and antioxidant effects.A Triazole Disulfide Compound Increases the Affinity of Hemoglobin for Oxygen and Reduces the Sickling of Human Sickle Cells.Prospects for early investigational therapies for sickle cell disease.Development and validation of an oxygen dissociation assay, a screening platform for discovering, and characterizing hemoglobin-oxygen affinity modifiers.
P2860
Q27727697-15E201AF-EE2A-4155-8AD9-20E749D729F0Q30837666-96226845-0BA4-4432-A603-CA10118B958FQ35661138-884125FD-8313-49DE-B72D-03C196064A01Q35981965-517A7CD0-F2AF-42D6-932C-D228BEFE9003Q36711629-2AFD2F0E-905E-45F9-ABEC-E214FD980CDEQ38948912-EAA4F3D0-7464-4D1C-BEA3-50D034E4D0DAQ39237387-D8C036D1-2C15-416D-8637-B961BD262D07Q39336717-3D3773A2-BFDE-4E39-A401-C5166D07DA87Q47996759-427F94DA-2FA2-4162-BFD4-848CE2435BDDQ52596367-4BF62E43-E0D3-4ABB-B9FA-8FCD574C5D2AQ53608275-BBF94450-4EA4-4331-A9E8-93EBECDB9668Q55318498-4EE473C3-A892-4DCA-8E11-665B60352B56
P2860
Identification of a Small Molecule that Increases Hemoglobin Oxygen Affinity and Reduces SS Erythrocyte Sickling
description
2014 nî lūn-bûn
@nan
2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Identification of a Small Mole ...... educes SS Erythrocyte Sickling
@ast
Identification of a Small Mole ...... educes SS Erythrocyte Sickling
@en
Identification of a Small Mole ...... educes SS Erythrocyte Sickling
@nl
type
label
Identification of a Small Mole ...... educes SS Erythrocyte Sickling
@ast
Identification of a Small Mole ...... educes SS Erythrocyte Sickling
@en
Identification of a Small Mole ...... educes SS Erythrocyte Sickling
@nl
prefLabel
Identification of a Small Mole ...... educes SS Erythrocyte Sickling
@ast
Identification of a Small Mole ...... educes SS Erythrocyte Sickling
@en
Identification of a Small Mole ...... educes SS Erythrocyte Sickling
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Identification of a Small Mole ...... educes SS Erythrocyte Sickling
@en
P2093
Akito Nakagawa
Dina Wassaf
Dominick Casalena
Francine E Lui
Jacqueline Meadows
Kenneth D Bloch
Martin K Safo
Michelle A Palmer
Revital Yefidoff-Freedman
Warren M Zapol
P2860
P304
P3181
P356
10.1021/CB500230B
P577
2014-10-17T00:00:00Z