Dicarba α-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors
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Conotoxin Interactions with α9α10-nAChRs: Is the α9α10-Nicotinic Acetylcholine Receptor an Important Therapeutic Target for Pain Management?Structure and function of μ-conotoxins, peptide-based sodium channel blockers with analgesic activityTransforming conotoxins into cyclotides: Backbone cyclization of P-superfamily conotoxinsAlanine scan of α-conotoxin RegIIA reveals a selective α3β4 nicotinic acetylcholine receptor antagonist.Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist.Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1.Strategies for the development of conotoxins as new therapeutic leads.Identifying key amino acid residues that affect α-conotoxin AuIB inhibition of α3β4 nicotinic acetylcholine receptors.Therapeutic conotoxins: a US patent literature survey.Redox-stable cyclic peptide inhibitors of the SPSB2-iNOS interaction.Enhancing the therapeutic potential of peptide toxins.α9-containing nicotinic acetylcholine receptors and the modulation of pain.αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtype.RgIA4 Potently Blocks Mouse α9α10 nAChRs and Provides Long Lasting Protection against Oxaliplatin-Induced Cold Allodynia.α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors.The Role of Disulfide Bond Replacements in Analogues of the Tarantula Toxin ProTx-II and Their Effects on Inhibition of the Voltage-Gated Sodium Ion Channel Nav1.7.Z-Selective olefin metathesis on peptides: investigation of side-chain influence, preorganization, and guidelines in substrate selectionMolecular Engineering of Conus Peptides as Therapeutic Leads.G-Protein Coupled Receptors Targeted by Analgesic Venom Peptides.Disulfide Bond Mimetics: Strategies and Challenges.Synthesis and in vitro bone cell activity of analogues of the cyclohexapeptide dianthin G.Structure activity relationship study on the peptide hormone preptin, a novel bone-anabolic agent for the treatment of osteoporosis.Role of CysI–CysIII Disulfide Bond on the Structure and Activity of α-Conotoxins at Human Neuronal Nicotinic Acetylcholine Receptors.
P2860
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P2860
Dicarba α-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors
description
2013 nî lūn-bûn
@nan
2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Dicarba α-conotoxin Vc1.1 anal ...... tylcholine and GABAB receptors
@ast
Dicarba α-conotoxin Vc1.1 anal ...... tylcholine and GABAB receptors
@en
Dicarba α-conotoxin Vc1.1 anal ...... tylcholine and GABAB receptors
@nl
type
label
Dicarba α-conotoxin Vc1.1 anal ...... tylcholine and GABAB receptors
@ast
Dicarba α-conotoxin Vc1.1 anal ...... tylcholine and GABAB receptors
@en
Dicarba α-conotoxin Vc1.1 anal ...... tylcholine and GABAB receptors
@nl
prefLabel
Dicarba α-conotoxin Vc1.1 anal ...... tylcholine and GABAB receptors
@ast
Dicarba α-conotoxin Vc1.1 anal ...... tylcholine and GABAB receptors
@en
Dicarba α-conotoxin Vc1.1 anal ...... tylcholine and GABAB receptors
@nl
P2093
P50
P356
P1433
P1476
Dicarba α-conotoxin Vc1.1 anal ...... tylcholine and GABAB receptors
@en
P2093
Andrea J Robinson
Andrew Hung
Bianca J van Lierop
Raymond S Norton
P304
P356
10.1021/CB4002393
P50
P577
2013-08-16T00:00:00Z