The structure of an MDM2-Nutlin-3a complex solved by the use of a validated MDM2 surface-entropy reduction mutant

The structure of an MDM2-Nutlin-3a complex solved by the use of a validated MDM2 surface-entropy reduction mutant

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http://www.wikidata.org/entity/Q27685287
Elucidation of Ligand-Dependent Modulation of Disorder-Order Transitions in the Oncoprotein MDM2Double Strain-Promoted Macrocyclization for the Rapid Selection of Cell-Active Stapled PeptidesEnergetic Landscape of MDM2-p53 Interactions by Computational Mutagenesis of the MDM2-p53 InteractionPathological unfoldomics of uncontrolled chaos: intrinsically disordered proteins and human diseasesStructure of a stapled peptide antagonist bound to nutlin-resistant Mdm2.A redox mechanism underlying nucleolar stress sensing by nucleophosminDiscovery of Novel Isatin-Based p53 InducersOn the origin of the stereoselective affinity of Nutlin-3 geometrical isomers for the MDM2 protein.Structure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes.Medicinal Chemistry Strategies to Disrupt the p53-MDM2/MDMX Interaction.Microsecond simulations of mdm2 and its complex with p53 yield insight into force field accuracy and conformational dynamics.Design of p53-derived peptides with cytotoxicity on breast cancer.
P2860

The structure of an MDM2-Nutlin-3a complex solved by the use of a validated MDM2 surface-entropy reduction mutant

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http://www.wikidata.org/entity/Q27685287
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2013 nî lūn-bûn
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2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2013 թվականի օգոստոսին հրատարակված գիտական հոդված
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2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年學術文章
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The structure of an MDM2-Nutli ...... rface-entropy reduction mutant
@ast
The structure of an MDM2-Nutli ...... rface-entropy reduction mutant
@en
The structure of an MDM2-Nutli ...... rface-entropy reduction mutant
@nl
type
label
The structure of an MDM2-Nutli ...... rface-entropy reduction mutant
@ast
The structure of an MDM2-Nutli ...... rface-entropy reduction mutant
@en
The structure of an MDM2-Nutli ...... rface-entropy reduction mutant
@nl
prefLabel
The structure of an MDM2-Nutli ...... rface-entropy reduction mutant
@ast
The structure of an MDM2-Nutli ...... rface-entropy reduction mutant
@en
The structure of an MDM2-Nutli ...... rface-entropy reduction mutant
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P356
P1433
P1476
The structure of an MDM2-Nutli ...... rface-entropy reduction mutant
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P698