The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation
about
Ubiquitylation of autophagy receptor Optineurin by HACE1 activates selective autophagy for tumor suppressionHECT and RING finger families of E3 ubiquitin ligases at a glanceFunctions of PARylation in DNA Damage Repair PathwaysExpanding proteostasis by membrane trafficking networksDangER: protein ovERload. Targeting protein degradation to treat myelomaRING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitinationBacterial effectors and their functions in the ubiquitin-proteasome system: insight from the modes of substrate recognitionTargeting the ubiquitin pathway for cancer treatmentProtein homeostasis as a therapeutic target for diseases of protein conformationThe zinc-binding region (ZBR) fragment of Emi2 can inhibit APC/C by targeting its association with the coactivator Cdc20 and UBE2C-mediated ubiquitylationHomopiperazine derivatives as a novel class of proteasome inhibitors with a unique mode of proteasome bindingA bacterial genetic selection system for ubiquitylation cascade discoveryGeneration of free ubiquitin chains is up-regulated in stress and facilitated by the HECT domain ubiquitin ligases UFD4 and HUL5.A decade of the anaphase-promoting complex in the nervous systemThe Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer's DiseaseDisrupting the networks of cancerStabilizing mutations of KLHL24 ubiquitin ligase cause loss of keratin 14 and human skin fragilityChanges in PUB22 Ubiquitination Modes Triggered by MITOGEN-ACTIVATED PROTEIN KINASE3 Dampen the Immune Response.The HBx oncoprotein of hepatitis B virus deregulates the cell cycle by promoting the intracellular accumulation and re-compartmentalization of the cellular deubiquitinase USP37.Chemical and semisynthesis of posttranslationally modified proteins.Proteomic Identification of Putative MicroRNA394 Target Genes in Arabidopsis thaliana Identifies Major Latex Protein Family Members Critical for Normal DevelopmentUbiquitin ligase SYVN1/HRD1 facilitates degradation of the SERPINA1 Z variant/α-1-antitrypsin Z variant via SQSTM1/p62-dependent selective autophagy.Deubiquitinating enzymes Ubp2 and Ubp15 regulate endocytosis by limiting ubiquitination and degradation of ARTsThe role of E3 ligases in the ubiquitin-dependent regulation of spermatogenesisAn ubiquitin-dependent balance between mitofusin turnover and fatty acids desaturation regulates mitochondrial fusion.A chaperone trap contributes to the onset of cystic fibrosis.Inhibition of proliferation and survival of diffuse large B-cell lymphoma cells by a small-molecule inhibitor of the ubiquitin-conjugating enzyme Ubc13-Uev1A.How the nucleus copes with proteotoxic stress.Suppression of the macrophage proteasome by ethanol impairs MHC class I antigen processing and presentation.In silico functional analyses and discovery of survival-associated microRNA signatures in pediatric osteosarcoma.20S proteasome activation promotes life span extension and resistance to proteotoxicity in Caenorhabditis elegansApplication of quantitative proteomics to the integrated analysis of the ubiquitylated and global proteomes of xenograft tumor tissuesA Point Mutation in the Ubiquitin Ligase RNF170 That Causes Autosomal Dominant Sensory Ataxia Destabilizes the Protein and Impairs Inositol 1,4,5-Trisphosphate Receptor-mediated Ca2+ SignalingAssociation of the von Hippel-Lindau protein with AUF1 and posttranscriptional regulation of VEGFA mRNA.Skp2 is a promising therapeutic target in breast cancer.Expanding the chemical cross-linking toolbox by the use of multiple proteases and enrichment by size exclusion chromatographyNewly discovered viral E3 ligase pK3 induces endoplasmic reticulum-associated degradation of class I major histocompatibility proteins and their membrane-bound chaperonesK63-linked ubiquitination in kinase activation and cancer.Enoxacin directly inhibits osteoclastogenesis without inducing apoptosisTumor suppressor functions of FBW7 in cancer development and progression.
P2860
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P2860
The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
name
The predator becomes the prey: ...... ubiquitylation and degradation
@ast
The predator becomes the prey: ...... ubiquitylation and degradation
@en
The predator becomes the prey: ...... biquitylation and degradation.
@nl
type
label
The predator becomes the prey: ...... ubiquitylation and degradation
@ast
The predator becomes the prey: ...... ubiquitylation and degradation
@en
The predator becomes the prey: ...... biquitylation and degradation.
@nl
prefLabel
The predator becomes the prey: ...... ubiquitylation and degradation
@ast
The predator becomes the prey: ...... ubiquitylation and degradation
@en
The predator becomes the prey: ...... biquitylation and degradation.
@nl
P2860
P3181
P356
P1476
The predator becomes the prey: ...... ubiquitylation and degradation
@en
P2093
Allan M. Weissman
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P2888
P304
P3181
P356
10.1038/NRM3173
P577
2011-08-23T00:00:00Z
P5875
P6179
1004119889