Structural basis for AMPK activation: natural and synthetic ligands regulate kinase activity from opposite poles by different molecular mechanisms - Wikidata - awgldk - TriplyDB

Structural basis for AMPK activation: natural and synthetic ligands regulate kinase activity from opposite poles by different molecular mechanisms

Structural basis for AMPK activation: natural and synthetic ligands regulate kinase activity from opposite poles by different molecular mechanisms

http://www.wikidata.org/entity/Q27694634

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Regulation of AMP-activated protein kinase by natural and synthetic activators Metabolism. AMP-activated protein kinase mediates mitochondrial fission in response to energy stress.The β subunit of yeast AMP-activated protein kinase directs substrate specificity in response to alkaline stress AMP-activated protein kinase: a cellular energy sensor that comes in 12 flavours AMPK in Yeast: The SNF1 (Sucrose Non-fermenting 1) Protein Kinase Complex.Effects of turmeric curcuminoids and metformin against central sensitivity to pain in mice.Effect of different γ-subunit isoforms on the regulation of AMPK Molecular Pathways: Is AMPK a Friend or a Foe in Cancer?Targeting AMPK: From Ancient Drugs to New Small-Molecule Activators.Oestrogen receptors interact with the α-catalytic subunit of AMP-activated protein kinase.Structural basis of AMPK regulation by adenine nucleotides and glycogen.Differential regulation by AMP and ADP of AMPK complexes containing different γ subunit isoforms.AMP-Activated Protein Kinase Signalling in Cancer and Cardiac Hypertrophy.Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding.Architectural plasticity of AMPK revealed by electron microscopy and X-ray crystallography Salsalate (Salicylate) Uncouples Mitochondria, Improves Glucose Homeostasis, and Reduces Liver Lipids Independent of AMPK-β1 Benzimidazole derivative small-molecule 991 enhances AMPK activity and glucose uptake induced by AICAR or contraction in skeletal muscle.Screening methods for AMP-activated protein kinase modulators: a patent review.Deconvoluting AMP-activated protein kinase (AMPK) adenine nucleotide binding and sensing The opposing actions of target of rapamycin and AMP-activated protein kinase in cell growth control.Probing the enzyme kinetics, allosteric modulation and activation of α1- and α2-subunit-containing AMP-activated protein kinase (AMPK) heterotrimeric complexes by pharmacological and physiological activators.Adenosine Monophosphate-Activated Protein Kinase (AMPK) as a Diverse Therapeutic Target: A Computational Perspective.AMPK: An Energy-Sensing Pathway with Multiple Inputs and Outputs.Phosphorylation of AMPK by upstream kinases is required for activity in mammalian cells.Targeting of AMP-activated protein kinase: prospects for computer-aided drug design.Structural and biochemical insights into the allosteric activation mechanism of AMP-activated protein kinase.Structure and Regulation of AMPK.In Vitro Methods to Study AMPK.AMP-Activated Protein Kinase: An Ubiquitous Signaling Pathway With Key Roles in the Cardiovascular System.AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance.Nutrient sensing modulates malaria parasite virulence.Identification of Direct Activator of Adenosine Monophosphate-Activated Protein Kinase (AMPK) by Structure-Based Virtual Screening and Molecular Docking Approach.The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs.Choreography of AMPK activation.AMP-activated protein kinase - not just an energy sensor.Redox state-dependent modulation of plant SnRK1 kinase activity differs from AMPK regulation in animals.Keeping the home fires burning: AMP-activated protein kinase.Discovering protein-ligand chalcogen bonding in the protein data bank using endocyclic sulfur-containing heterocycles as ligand search subsets.AMPK in skeletal muscle function and metabolism.A concise review on advances in development of small molecule anti-inflammatory therapeutics emphasising AMPK: An emerging target.

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P2860

Structural basis for AMPK activation: natural and synthetic ligands regulate kinase activity from opposite poles by different molecular mechanisms

http://www.wikidata.org/entity/Q27694634

description

2014 nî lūn-bûn

@nan

2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Structural basis for AMPK acti ...... different molecular mechanisms

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Structural basis for AMPK acti ...... different molecular mechanisms

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Structural basis for AMPK acti ...... different molecular mechanisms

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type

label

Structural basis for AMPK acti ...... different molecular mechanisms

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Structural basis for AMPK acti ...... different molecular mechanisms

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Structural basis for AMPK acti ...... different molecular mechanisms

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prefLabel

Structural basis for AMPK acti ...... different molecular mechanisms

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Structural basis for AMPK acti ...... different molecular mechanisms

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Structural basis for AMPK acti ...... different molecular mechanisms

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J.STR.2014.06.009

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Structural basis for AMPK acti ...... different molecular mechanisms

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Aaron C Smith

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Allan R Reyes

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Allyn T Londregan

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Edward L Conn

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Francis Rajamohan

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Hong Wang

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James A Landro

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Jane M Withka

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Janice Brown

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Jessica Ward

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1161-1172

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scholarly article

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2393309

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10.1016/J.STR.2014.06.009

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8

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22

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25066137

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