A cautionary tale of structure-guided inhibitor development against an essential enzyme in the aspartate-biosynthetic pathway
about
Elaboration of a fragment library hit produces potent and selective aspartate semialdehyde dehydrogenase inhibitors.Structure of a fungal form of aspartate semialdehyde dehydrogenase from Cryptococcus neoformans.Structure of a fungal form of aspartate-semialdehyde dehydrogenase from Aspergillus fumigatus.Crystal Structure of the LysY·LysW Complex from Thermus thermophilus.
P2860
A cautionary tale of structure-guided inhibitor development against an essential enzyme in the aspartate-biosynthetic pathway
description
2014 nî lūn-bûn
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2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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name
A cautionary tale of structure ...... aspartate-biosynthetic pathway
@ast
A cautionary tale of structure ...... aspartate-biosynthetic pathway
@en
A cautionary tale of structure ...... aspartate-biosynthetic pathway
@nl
type
label
A cautionary tale of structure ...... aspartate-biosynthetic pathway
@ast
A cautionary tale of structure ...... aspartate-biosynthetic pathway
@en
A cautionary tale of structure ...... aspartate-biosynthetic pathway
@nl
prefLabel
A cautionary tale of structure ...... aspartate-biosynthetic pathway
@ast
A cautionary tale of structure ...... aspartate-biosynthetic pathway
@en
A cautionary tale of structure ...... aspartate-biosynthetic pathway
@nl
P2093
P2860
P1476
A cautionary tale of structure ...... aspartate-biosynthetic pathway
@en
P2093
Alexander G Pavlovsky
Bharani Thangavelu
Pravin Bhansali
Ronald E Viola
P2860
P304
P356
10.1107/S1399004714023979
P577
2014-12-01T00:00:00Z