Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions
about
M1 aminopeptidases as drug targets: broad applications or therapeutic niche?Proteases as antimalarial targets: strategies for genetic, chemical, and therapeutic validation.Generation of AMBER force field parameters for zinc centres of M1 and M17 family aminopeptidases.Design, synthesis, conformational and molecular docking study of some novel acyl hydrazone based molecular hybrids as antimalarial and antimicrobial agents.Two cap residues in the S1 subsite of a Plasmodium falciparum M1-family aminopeptidase promote broad specificity and enhance catalysis.
P2860
Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions
description
2016 nî lūn-bûn
@nan
2016 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի մարտին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Potent dual inhibitors of Plas ...... tion of S1 pocket interactions
@ast
Potent dual inhibitors of Plas ...... tion of S1 pocket interactions
@en
Potent dual inhibitors of Plas ...... tion of S1 pocket interactions
@nl
type
label
Potent dual inhibitors of Plas ...... tion of S1 pocket interactions
@ast
Potent dual inhibitors of Plas ...... tion of S1 pocket interactions
@en
Potent dual inhibitors of Plas ...... tion of S1 pocket interactions
@nl
prefLabel
Potent dual inhibitors of Plas ...... tion of S1 pocket interactions
@ast
Potent dual inhibitors of Plas ...... tion of S1 pocket interactions
@en
Potent dual inhibitors of Plas ...... tion of S1 pocket interactions
@nl
P2093
P50
P1476
Potent dual inhibitors of Plas ...... tion of S1 pocket interactions
@en
P2093
Alessandro Paiardini
Chiara Ruggeri
John P Holleran
Natalie B Vinh
Rebecca S Bamert
P356
10.1016/J.EJMECH.2016.01.015
P50
P577
2016-03-03T00:00:00Z