about
Two-pronged attack: dual inhibition of Plasmodium falciparum M1 and M17 metalloaminopeptidases by a novel series of hydroxamic acid-based inhibitorsPotent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactionsMechanistic insights into allosteric structure-function relationships at the M1 muscarinic acetylcholine receptor.Biased allosteric modulation at the CaS receptor engendered by structurally diverse calcimimeticsScreening the Medicines for Malaria Venture "Malaria Box" against the Plasmodium falciparum aminopeptidases, M1, M17 and M18.Discovery of a Novel Class of Negative Allosteric Modulator of the Dopamine D2 Receptor Through Fragmentation of a Bitopic Ligand.Molecular determinants of allosteric modulation at the M1 muscarinic acetylcholine receptor.Synthesis and characterization of high-affinity 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human β-adrenoceptors.GPCRs through the keyhole: the role of protein flexibility in ligand binding to β-adrenoceptors.Synthesis and in vitro and in vivo characterization of highly β1-selective β-adrenoceptor partial agonists.4-Phenylpyridin-2-one Derivatives: A Novel Class of Positive Allosteric Modulator of the M1 Muscarinic Acetylcholine Receptor.Synthesis and pharmacological profiling of analogues of benzyl quinolone carboxylic acid (BQCA) as allosteric modulators of the M1 muscarinic receptor.Structure-activity study of N-((trans)-4-(2-(7-cyano-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)cyclohexyl)-1H-indole-2-carboxamide (SB269652), a bitopic ligand that acts as a negative allosteric modulator of the dopamine D2 receptor.A Thieno[2,3-d]pyrimidine Scaffold is a Novel Negative Allosteric Modulator of the Dopamine D2 Receptor.Structure-Kinetic Profiling of Haloperidol Analogues at the Human Dopamine D2 Receptor27th Annual GP2A Medicinal Chemistry Conference
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description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Shailesh N Mistry
@ast
Shailesh N Mistry
@en
Shailesh N Mistry
@es
Shailesh N Mistry
@nl
type
label
Shailesh N Mistry
@ast
Shailesh N Mistry
@en
Shailesh N Mistry
@es
Shailesh N Mistry
@nl
prefLabel
Shailesh N Mistry
@ast
Shailesh N Mistry
@en
Shailesh N Mistry
@es
Shailesh N Mistry
@nl
P106
P1153
54780187300
P31
P496
0000-0002-2252-1689