Structural basis for therapeutic inhibition of complement C5 - Wikidata - awgldk - TriplyDB

Structural basis for therapeutic inhibition of complement C5

Structural basis for therapeutic inhibition of complement C5

http://www.wikidata.org/entity/Q27704314

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Saliva of Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) inhibits classical and alternative complement pathways New milestones ahead in complement-targeted therapy.Anti-complement component 5 antibody targeting MG4 domain inhibits choroidal neovascularization.Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function.Protection of host cells by complement regulators.Structural insight into proteolytic activation and regulation of the complement system.On the state of crystallography at the dawn of the electron microscopy revolution.Gene Duplication and Protein Evolution in Tick-Host Interactions.Stratification of responders towards eculizumab using a structural epitope mapping strategy.The crystal structure of full-length Sizzled from Xenopus laevis yields insights into Wnt-antagonistic function of secreted Frizzled-related proteins.Incomplete inhibition by eculizumab: mechanistic evidence for residual C5 activity during strong complement activation.The MFHR1 Fusion Protein Is a Novel Synthetic Multitarget Complement Inhibitor with Therapeutic Potential.Expanding horizons in complement drug discovery: challenges and emerging strategies.

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P2860

Structural basis for therapeutic inhibition of complement C5

http://www.wikidata.org/entity/Q27704314

description

2016 nî lūn-bûn

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2016 թուականի Մարտին հրատարակուած գիտական յօդուած

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2016 թվականի մարտին հրատարակված գիտական հոդված

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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Structural basis for therapeutic inhibition of complement C5

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Structural basis for therapeutic inhibition of complement C5

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Structural basis for therapeutic inhibition of complement C5

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Structural basis for therapeutic inhibition of complement C5

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Structural basis for therapeutic inhibition of complement C5

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Structural basis for therapeutic inhibition of complement C5

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Structural basis for therapeutic inhibition of complement C5

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Structural basis for therapeutic inhibition of complement C5

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Structural basis for therapeutic inhibition of complement C5

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Nature Structural & Molecular Biology

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Structural basis for therapeutic inhibition of complement C5

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Devon Sheppard

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Matthijs M Jore

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Miles A Nunn

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Natalie M Barber

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P2860

Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex

Full-length transcriptome assembly from RNA-Seq data without a reference genome

The Structure of OMCI, a Novel Lipocalin Inhibitor of the Complement System

Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex

Structure of and influence of a tick complement inhibitor on human complement component 5

Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor

Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus

Bifunctional Lipocalin Ameliorates Murine Immune Complex-induced Acute Lung Injury

Structural Basis for the Function of Complement Component C4 within the Classical and Lectin Pathways of Complement

Inference of macromolecular assemblies from crystalline state

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10.1038/NSMB.3196

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5

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23

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