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The HaloTag: Improving Soluble Expression and Applications in Protein Functional AnalysisMechanism of Inhibition of Novel Tryptophan Hydroxylase Inhibitors Revealed by Co-crystal Structures and Kinetic AnalysisEditorialA Cell-based beta-Lactamase Reporter Gene Assay for the CREB Signaling Pathway.The use of AlphaScreen technology in HTS: current statusCellular Ser/Thr-kinase assays using generic peptide substrates.The imaging probe development center and the production of molecular imaging probesA high throughput assay to identify small molecule modulators of prostatic acid phosphatase.A homogenous luminescent proximity assay for 14-3-3 interactions with both phosphorylated and nonphosphorylated client peptides.Development of improved models for phosphodiesterase-4 inhibitors with a multi-conformational structure-based QSAR method.In vitro viability and cytotoxicity testing and same-well multi-parametric combinations for high throughput screeningComparative docking assessment of glucokinase interactions with its allosteric activatorsNovel Inhibitors of E. coli RecA ATPase Activity.High throughput screening for inhibitors of alpha-galactosidase.A grid algorithm for high throughput fitting of dose-response curve data.A rapid, inexpensive high throughput screen method for neurite outgrowthDevelopment of a cell-based high-throughput assay to screen for inhibitors of organic anion transporting polypeptides 1B1 and 1B3.A High Throughput Assay for Discovery of Bacterial β-Glucuronidase Inhibitors.Two High Throughput Screen Assays for Measurement of TNF-α in THP-1 CellsDevelopment and Implementation of a High Throughput Screen for the Human Sperm-Specific Isoform of Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDHS).An automated approach to efficiently reformat a large collection of compounds.Methods for Activity Analysis of the Proteins that Regulate Histone MethylationFabry disease - current treatment and new drug development.High-Throughput Multiplexed Quantitation of Protein Aggregation and Cytotoxicity in a Huntington's Disease Model.NRF2 Oxidative Stress Induced by Heavy Metals is Cell Type Dependent.Promoting illiteracy in epigenetics: an emerging therapeutic strategy.Quantitative proteomic approaches to studying histone modifications.Development of RNA aptamer and its ligand binding assay on microchip electrophoresis.A Dual Reporter Splicing Assay Using HaloTag-containing Proteins.Development of a dehalogenase-based protein fusion tag capable of rapid, selective and covalent attachment to customizable ligands.A homogenous luminescence assay reveals novel inhibitors for giardia lamblia carbamate kinaseGlutamatergic Synaptic Dysfunction and Obsessive-Compulsive DisorderComparison on functional assays for Gq-coupled GPCRs by measuring inositol monophospate-1 and intracellular calcium in 1536-well plate format.HTS-compatible beta-lactamase transcriptional reporter gene assay for interrogating the heat shock response pathway.HTRF: A technology tailored for drug discovery - a review of theoretical aspects and recent applications.Chemical biology of lysine demethylases.Targets in epigenetics: inhibiting the methyl writers of the histone codeStructural Chemistry of Human SET Domain Protein Methyltransferases.Drug discovery toward antagonists of methyl-lysine binding proteinsHaloTag, a Platform Technology for Protein Analysis
P1433
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P1433
description
revista científica
@es
revue scientifique
@fr
rivista scientifica
@it
scientific journal
@en
wetenschappelijk tijdschrift van Bentham Science Publishers
@nl
wissenschaftliche Fachzeitschrift
@de
name
Current Chemical Genomics
@ast
Current Chemical Genomics
@de
Current Chemical Genomics
@en
Current Chemical Genomics
@es
Current Chemical Genomics
@fr
Current chemical genomics
@nl
type
label
Current Chemical Genomics
@ast
Current Chemical Genomics
@de
Current Chemical Genomics
@en
Current Chemical Genomics
@es
Current Chemical Genomics
@fr
Current chemical genomics
@nl
altLabel
Curr Chem Genomics
@en
Curr. Chem. Genomics
@en
prefLabel
Current Chemical Genomics
@ast
Current Chemical Genomics
@de
Current Chemical Genomics
@en
Current Chemical Genomics
@es
Current Chemical Genomics
@fr
Current chemical genomics
@nl
P3181
P1055
P1156
19700174983
P1476
Current Chemical Genomics
@en