Development of a cell-based high-throughput assay to screen for inhibitors of organic anion transporting polypeptides 1B1 and 1B3.
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OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamiliesSLC transporters as therapeutic targets: emerging opportunitiesRole of OATP-1B1 and/or OATP-1B3 in hepatic disposition of tyrosine kinase inhibitorsInhibition of OATP-1B1 and OATP-1B3 by tyrosine kinase inhibitorsFunctional expression of the 11 human Organic Anion Transporting Polypeptides in insect cells reveals that sodium fluorescein is a general OATP substrate.Influence of OATP1B1 Function on the Disposition of Sorafenib-β-D-GlucuronideFluorescence-based assays for the assessment of drug interaction with the human transporters OATP1B1 and OATP1B3The influence of herbal medicine ursolic acid on the uptake of rosuvastatin mediated by OATP1B1*1a and *5.Transporter function and cyclic AMP turnover in normal colonic mucosa from patients with and without colorectal neoplasia.Aggregate culture: A more accurate predictor of microcystin toxicity for risk assessmentIsolation of modulators of the liver-specific organic anion-transporting polypeptides (OATPs) 1B1 and 1B3 from Rollinia emarginata Schlecht (Annonaceae).A Novel Fluorescence Resonance Energy Transfer-Based Screen in High-Throughput Format To Identify Inhibitors of Malarial and Human Glucose TransportersDrug-drug interaction studies: regulatory guidance and an industry perspectiveThe evolution of the OATP hepatic uptake transport protein family in DMPK sciences: from obscure liver transporters to key determinants of hepatobiliary clearance.Organic anion-transporting polypeptides: a novel approach for cancer therapy.Transporter-mediated drug-drug interactions with oral antidiabetic drugs.Nature and uses of fluorescent dyes for drug transporter studies.Assessment of drug metabolism enzyme and transporter pharmacogenetics in drug discovery and early development: perspectives of the I-PWG.Identification of Novel Inhibitors of Organic Anion Transporting Polypeptides 1B1 and 1B3 (OATP1B1 and OATP1B3) Using a Consensus Vote of Six Classification Models.Differential Expression of OATP1B3 Mediates Unconjugated Testosterone Influx.Resveratrol and its major sulfated conjugates are substrates of organic anion transporting polypeptides (OATPs): impact on growth of ZR-75-1 breast cancer cells.The role of organic anion transporting polypeptides in drug absorption, distribution, excretion and drug-drug interactions.Sulfate metabolites provide an intracellular pool for resveratrol generation and induce autophagy with senescence.Effects of anthocyans on the expression of organic anion transporting polypeptides (SLCOs/OATPs) in primary human hepatocytes.Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.Effects of natural products on the function of human organic anion transporting polypeptide 1B1.Hepatic transporter drug-drug interactions: an evaluation of approaches and methodologies.Inter-Subject Variability in OCT1 Activity in 27 Batches of Cryopreserved Human Hepatocytes and Association with OCT1 mRNA Expression and Genotype.Interactions of the active components of Punica granatum (pomegranate) with the essential renal and hepatic human Solute Carrier transporters.Identification of novel cell-impermeant fluorescent substrates for testing the function and drug interaction of Organic Anion-Transporting Polypeptides, OATP1B1/1B3 and 2B1.Oatp58Dc contributes to blood-brain barrier function by excluding organic anions from the Drosophila brain.Hepatic Uptake Mechanism of Ophiopogonin D Mediated by Organic Anion Transporting Polypeptides.Hepatic Transport of 25-Hydroxyvitamin D3 Conjugates: A Mechanism of 25-Hydroxyvitamin D3 Delivery to the Intestinal Tract.Development of a high-throughput mass spectrometry based analytical method to support an in vitro OATP1B1 inhibition screening assay.
P2860
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P2860
Development of a cell-based high-throughput assay to screen for inhibitors of organic anion transporting polypeptides 1B1 and 1B3.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Development of a cell-based hi ...... ting polypeptides 1B1 and 1B3.
@ast
Development of a cell-based hi ...... ting polypeptides 1B1 and 1B3.
@en
type
label
Development of a cell-based hi ...... ting polypeptides 1B1 and 1B3.
@ast
Development of a cell-based hi ...... ting polypeptides 1B1 and 1B3.
@en
prefLabel
Development of a cell-based hi ...... ting polypeptides 1B1 and 1B3.
@ast
Development of a cell-based hi ...... ting polypeptides 1B1 and 1B3.
@en
P2093
P2860
P1476
Development of a cell-based hi ...... ting polypeptides 1B1 and 1B3.
@en
P2093
Amanda Obaidat
Bruno Hagenbuch
Chunshan Gui
Rathnam Chaguturu
P2860
P356
10.2174/1875397301004010001
P577
2010-03-01T00:00:00Z