X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design
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Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activityCrystal structure of full-length human collagenase 3 (MMP-13) with peptides in the active site defines exosites in the catalytic domainThe metzincins--topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a superfamily of zinc-peptidasesCrystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzymeThe 1.8-A crystal structure of a matrix metalloproteinase 8-barbiturate inhibitor complex reveals a previously unobserved mechanism for collagenase substrate recognitionDeterminants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analoguesThe structural basis for substrate and inhibitor selectivity of the anthrax lethal factorStructural insights into triple-helical collagen cleavage by matrix metalloproteinase 1Structural basis for matrix metalloproteinase 1-catalyzed collagenolysis.Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product2 angstrom X-ray structure of adamalysin II complexed with a peptide phosphonate inhibitor adopting a retro-binding modeHydrolysis of triple-helical collagen peptide models by matrix metalloproteinasesStructural differences of matrix metalloproteinases. Homology modeling and energy minimization of enzyme-substrate complexesHydrolysis of a broad spectrum of extracellular matrix proteins by human macrophage elastaseA unique substrate recognition profile for matrix metalloproteinase-2.Hepatoprotective activity of chrysin is mediated through TNF-α in chemically-induced acute liver damage: An in vivo study and molecular modeling.Potent tumor targeting drug release system comprising MMP-2 specific peptide fragment with self-assembling characteristicsMatrix metalloproteinases and collagen catabolism.Triple-helical peptide analysis of collagenolytic protease activity.Structural basis of the matrix metalloproteinases and their physiological inhibitors, the tissue inhibitors of metalloproteinases.A structure-based catalytic mechanism for the xanthine oxidase family of molybdenum enzymes.pH- and temperature-dependence of functional modulation in metalloproteinases. A comparison between neutrophil collagenase and gelatinases A and B.Enzyme-catalyzed gel proteolysis: an anomalous diffusion-controlled mechanism.A residue in the S2 subsite controls substrate selectivity of matrix metalloproteinase-2 and matrix metalloproteinase-9.Collagenase: a key enzyme in collagen turnover.A novel mechanism of latency in matrix metalloproteinases.Highly sensitive single-fibril erosion assay demonstrates mechanochemical switch in native collagen fibrils.Involvement of a region near valine-69 of tissue inhibitor of metalloproteinases (TIMP)-1 in the interaction with matrix metalloproteinase 3 (stromelysin 1).Three-dimensional structure of fibrolase, the fibrinolytic enzyme from southern copperhead venom, modeled from the X-ray structure of adamalysin II and atrolysin C.QM/MM linear response method distinguishes ligand affinities for closely related metalloproteins.A combination of docking, QM/MM methods, and MD simulation for binding affinity estimation of metalloprotein ligands.Structures of adamalysin II with peptidic inhibitors. Implications for the design of tumor necrosis factor alpha convertase inhibitors.Analysis of zinc binding sites in protein crystal structures.Pyrimidine-2,4,6-Triones: a new effective and selective class of matrix metalloproteinase inhibitors.Family-wide characterization of matrix metalloproteinases from Arabidopsis thaliana reveals their distinct proteolytic activity and cleavage site specificity.
P2860
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P2860
X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design
description
1995 nî lūn-bûn
@nan
1995 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մարտին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
X-ray structures of human neut ...... nding and rational drug design
@ast
X-ray structures of human neut ...... nding and rational drug design
@en
X-ray structures of human neut ...... nding and rational drug design
@nl
type
label
X-ray structures of human neut ...... nding and rational drug design
@ast
X-ray structures of human neut ...... nding and rational drug design
@en
X-ray structures of human neut ...... nding and rational drug design
@nl
prefLabel
X-ray structures of human neut ...... nding and rational drug design
@ast
X-ray structures of human neut ...... nding and rational drug design
@en
X-ray structures of human neut ...... nding and rational drug design
@nl
P2093
P2860
P1433
P1476
X-ray structures of human neut ...... nding and rational drug design
@en
P2093
H Tschesche
J C Powers
P Reinemer
P2860
P304
P356
10.1111/J.1432-1033.1995.TB20329.X
P407
P577
1995-03-15T00:00:00Z