26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity
about
The structural basis of repertoire shift in an immune response to phosphocholineCrystal structure of a recombinant anti-estradiol Fab fragment in complex with 17beta -estradiolStructural insights into steroid hormone binding: the crystal structure of a recombinant anti-testosterone Fab fragment in free and testosterone-bound formsCritical contribution of aromatic rings to specific recognition of polyether rings. The case of ciguatoxin CTX3C-ABC and its specific antibody 1C49Closely related antibody receptors exploit fundamentally different strategies for steroid recognitionThe testosterone binding mechanism of an antibody derived from a naïve human scFv libraryIn vitro scanning saturation mutagenesis of an antibody binding pocket.Isolation of high-affinity ligand-binding proteins by periplasmic expression with cytometric screening (PECS).Quantitative analysis of the effect of the mutation frequency on the affinity maturation of single chain Fv antibodies.Phage display-selected sequences of the heavy-chain CDR3 loop of the anti-digoxin antibody 26-10 define a high affinity binding site for position 16-substituted analogs of digoxin.Synthetic antibody libraries focused towards peptide ligands.Molecular similarity methods for predicting cross-reactivity with therapeutic drug monitoring immunoassays.Chemoinformatic methods for predicting interference in drug of abuse/toxicology immunoassaysSymmetry of Fv architecture is conducive to grafting a second antibody binding site in the Fv region.On the calculation of absolute macromolecular binding free energiesFunctional production and characterization of a fibrin-specific single-chain antibody fragment from Bacillus subtilis: effects of molecular chaperones and a wall-bound protease on antibody fragment production.Cell surface display yields evolvable, clickable antibody fragments.Contribution of a single heavy chain residue to specificity of an anti-digoxin monoclonal antibody.Modifying specificity of antidigoxin antibodies using insertional mutagenesis.Structural basis for DNA strand separation by a hexameric replicative helicase.Effects of mutation at the D-JH junction on affinity, specificity, and idiotypy of anti-progesterone antibody DB3.Functional characterization of two anti-estradiol antibodies as deduced from modelling and site-directed mutagenesis experiments.Functional characterization of an anti-estradiol antibody by site-directed mutagenesis and molecular modelling: modulation of binding properties and prominent role of the V(L) domain in estradiol recognition.Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein.Computational Design of Ligand Binding Proteins.Gyre and gimble: a maximum-likelihood replacement for Patterson correlation refinement.A recipe for ligand-binding proteins
P2860
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P2860
26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity
description
1993 nî lūn-bûn
@nan
1993 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity
@ast
26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity
@en
26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity
@nl
type
label
26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity
@ast
26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity
@en
26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity
@nl
prefLabel
26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity
@ast
26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity
@en
26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity
@nl
P2093
P2860
P356
P1476
26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity
@en
P2093
L C Sieker
M N Margolies
P D Jeffrey
R K Strong
R L Campbell
P2860
P304
P356
10.1073/PNAS.90.21.10310
P407
P577
1993-11-01T00:00:00Z