Routes to catalysis: structure of a catalytic antibody and comparison with its natural counterpart
about
Allosteric regulation of catalytic activity: Escherichia coli aspartate transcarbamoylase versus yeast chorismate mutaseSubstrate conformational transitions in the active site of chorismate mutase: their role in the catalytic mechanismInsights into antibody catalysis: structure of an oxygenation catalyst at 1.9-angstrom resolutionA glutamate residue in the catalytic center of the yeast chorismate mutase restricts enzyme activity to acidic conditionsA strategically positioned cation is crucial for efficient catalysis by chorismate mutaseCrystal Structures of a Quorum-quenching AntibodyThe crystal structure of allosteric chorismate mutase at 2.2-A resolutionCrystal structure of Taq DNA polymerase in complex with an inhibitory Fab: the Fab is directed against an intermediate in the helix-coil dynamics of the enzymeElectrostatic transition state stabilization rather than reactant destabilization provides the chemical basis for efficient chorismate mutase catalysis.Investigating and Engineering Enzymes by Genetic Selection.Selection of ribozymes that catalyse multiple-turnover Diels-Alder cycloadditions by using in vitro compartmentalization.Transition-state charge stabilization through multiple non-covalent interactions in the guanidinium-catalyzed enantioselective Claisen rearrangementThe near attack conformation approach to the study of the chorismate to prephenate reaction.An active enzyme constructed from a 9-amino acid alphabet.Mechanistically different catalytic antibodies obtained from immunization with a single transition-state analogDirect selection for a catalytic mechanism from combinatorial antibody libraries.Modulation of the allosteric equilibrium of yeast chorismate mutase by variation of a single amino acid residuePreliminary X-ray crystallographic analysis of the secreted chorismate mutase from Mycobacterium tuberculosis: a tricky crystallization problem solved.Carbanion-accelerated Claisen rearrangements: asymmetric induction with chiral phosphorus-stabilized anionsAsymmetric Enzymatic Synthesis of Allylic Amines: A Sigmatropic Rearrangement Strategy.Selection of linkers for a catalytic single-chain antibody using phage display technology.Exploring the active site of chorismate mutase by combinatorial mutagenesis and selection: the importance of electrostatic catalysis.Computational enzyme design.The structural repertoire of the human V kappa domainCatalytic antibodies--reaching adolescence?Biocatalytic Synthesis of Allylic and Allenyl Sulfides through a Myoglobin-Catalyzed Doyle-Kirmse Reaction.On the generation of catalytic antibodies by transition state analogues.
P2860
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P2860
Routes to catalysis: structure of a catalytic antibody and comparison with its natural counterpart
description
1994 nî lūn-bûn
@nan
1994 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Routes to catalysis: structure ...... n with its natural counterpart
@ast
Routes to catalysis: structure ...... n with its natural counterpart
@en
Routes to catalysis: structure ...... n with its natural counterpart
@nl
type
label
Routes to catalysis: structure ...... n with its natural counterpart
@ast
Routes to catalysis: structure ...... n with its natural counterpart
@en
Routes to catalysis: structure ...... n with its natural counterpart
@nl
prefLabel
Routes to catalysis: structure ...... n with its natural counterpart
@ast
Routes to catalysis: structure ...... n with its natural counterpart
@en
Routes to catalysis: structure ...... n with its natural counterpart
@nl
P2093
P356
P1433
P1476
Routes to catalysis: structure ...... n with its natural counterpart
@en
P2093
P304
P356
10.1126/SCIENCE.8303271
P407
P577
1994-02-04T00:00:00Z