Refined structures of substrate-bound and phosphate-bound thymidylate synthase from Lactobacillus casei

Refined structures of substrate-bound and phosphate-bound thymidylate synthase from Lactobacillus casei

Item
http://www.wikidata.org/entity/Q27732003
Crystal structure of a deletion mutant of human thymidylate synthase Δ (7-29) and its ternary complex with Tomudex and dUMPThe structure of Enterococcus faecalis thymidylate synthase provides clues about folate bacterial metabolismPromotion of purine nucleotide binding to thymidylate synthase by a potent folate analogue inhibitor, 1843U89Structure of the Varicella Zoster Virus Thymidylate Synthase Establishes Functional and Structural Similarities as the Human Enzyme and Potentiates Itself as a Target of BrivudineSeeking an ancient enzyme in Methanococcus jannaschii using ORF, a program based on predicted secondary structure comparisonsClassification of ligand molecules in PDB with graph match-based structural superposition.Thymidylate synthase inhibition: a structure-based rationale for drug design.The role of protein dynamics in thymidylate synthase catalysis: variants of conserved 2'-deoxyuridine 5'-monophosphate (dUMP)-binding Tyr-261Interaction of thymidylate synthase with the 5'-thiophosphates, 5'-dithiophosphates, 5'-H-phosphonates and 5'-S-thiosulfates of 2'-deoxyuridine, thymidine and 5-fluoro-2'-deoxyuridine.Mechanistic characterization of Toxoplasma gondii thymidylate synthase (TS-DHFR)-dihydrofolate reductase. Evidence for a TS intermediate and TS half-sites reactivity.Probing electrostatic channeling in protozoal bifunctional thymidylate synthase-dihydrofolate reductase using site-directed mutagenesis.Isolation and characterization of thymitaq (AG337) and 5-fluoro-2-deoxyuridylate-resistant mutants of human thymidylate synthase from ethyl methanesulfonate-exposed human sarcoma HT1080 cells.Structure of and kinetic channelling in bifunctional dihydrofolate reductase-thymidylate synthase.Ligand solvation in molecular docking.Probing the folate-binding site of human thymidylate synthase by site-directed mutagenesis. Generation of mutants that confer resistance to raltitrexed, Thymitaq, and BW1843U89.An electrostatic highway.
P2860

Refined structures of substrate-bound and phosphate-bound thymidylate synthase from Lactobacillus casei

Item
http://www.wikidata.org/entity/Q27732003
description
1993 nî lūn-bûn
@nan
1993 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Refined structures of substrat ...... thase from Lactobacillus casei
@ast
Refined structures of substrat ...... thase from Lactobacillus casei
@en
Refined structures of substrat ...... thase from Lactobacillus casei
@nl
type
label
Refined structures of substrat ...... thase from Lactobacillus casei
@ast
Refined structures of substrat ...... thase from Lactobacillus casei
@en
Refined structures of substrat ...... thase from Lactobacillus casei
@nl
prefLabel
Refined structures of substrat ...... thase from Lactobacillus casei
@ast
Refined structures of substrat ...... thase from Lactobacillus casei
@en
Refined structures of substrat ...... thase from Lactobacillus casei
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P356
P1433
P1476
Refined structures of substrat ...... thase from Lactobacillus casei
@en
P2093
P304
P31
P356
P407
P433
P478
P577
P5875
P698