The prosegment-subtilisin BPN' complex: crystal structure of a specific 'foldase'
about
Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegmentMolecular mechanisms for the conversion of zymogens to active proteolytic enzymesCleavage targets and the D-arginine-based inhibitors of the West Nile virus NS3 processing proteinaseStructural basis of profactor D activation: from a highly flexible zymogen to a novel self-inhibited serine protease, complement factor DCrystal structure of unautoprocessed precursor of subtilisin from a hyperthermophilic archaeon: evidence for Ca2+-induced foldingStructural basis for the autoprocessing of zinc metalloproteases in the thermolysin familyRegulation of an intracellular subtilisin protease activity by a short propeptide sequence through an original combined dual mechanismStructural and Functional Analyses Reveal That Staphylococcus aureus Antibiotic Resistance Factor HmrA Is a Zinc-dependent EndopeptidaseStructural and functional analysis of the CspB protease required for Clostridium spore germinationUnderstanding specificity of the mycosin proteases in ESX/type VII secretion by structural and functional analysisIncrease in activation rate of Pro-Tk-subtilisin by a single nonpolar-to-polar amino acid substitution at the hydrophobic core of the propeptide domainThe putative propeptide of MycP1 in mycobacterial type VII secretion system does not inhibit protease activity but improves protein stabilitySolution NMR structure of a sheddase inhibitor prodomain from the malarial parasite Plasmodium falciparumThe malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisinA novel Plasmodium-specific prodomain fold regulates the malaria drug target SUB1 subtilaseCrystal structure of calcium-independent subtilisin BPN' with restored thermal stability folded without the prodomainStructure of alpha-lytic protease complexed with its pro regionDirected evolution converts subtilisin E into a functional equivalent of thermitaseSubtilase SprP exerts pleiotropic effects in Pseudomonas aeruginosaBiosynthesis and enzymatic characterization of human SKI-1/S1P and the processing of its inhibitory prosegmentActivation of the furin endoprotease is a multiple-step process: requirements for acidification and internal propeptide cleavageThe ordered and compartment-specfific autoproteolytic removal of the furin intramolecular chaperone is required for enzyme activation.Botulinum neurotoxin heavy chain belt as an intramolecular chaperone for the light chainAutocatalytic activation of the furin zymogen requires removal of the emerging enzyme's N-terminus from the active site.Structural and energetic determinants of the S1-site specificity in serine proteases.Prokaryote-derived protein inhibitors of peptidases: A sketchy occurrence and mostly unknown functionStructure of a switchable subtilisin complexed with a substrate and with the activator azideCrystallographic evidence that the dinuclear copper center of tyrosinase is flexible during catalysis.Ca2+-dependent maturation of subtilisin from a hyperthermophilic archaeon, Thermococcus kodakaraensis: the propeptide is a potent inhibitor of the mature domain but is not required for its foldingInsights from bacterial subtilases into the mechanisms of intramolecular chaperone-mediated activation of furinPlasmodium subtilisin-like protease 1 (SUB1): insights into the active-site structure, specificity and function of a pan-malaria drug target.Macromolecular Crystallography and Structural Biology Databases at NIST.Kinetic stability as a mechanism for protease longevity.Bypassing the kinetic trap of serpin protein folding by loop extension.Selection for improved subtiligases by phage display.Tautomerism, acid-base equilibria, and H-bonding of the six histidines in subtilisin BPN' by NMRApplication of structural dynamic approaches provide novel insights into the enzymatic mechanism of the tumor necrosis factor-alpha-converting enzymeMolecular basis for auto- and hetero-catalytic maturation of a thermostable subtilase from thermophilic Bacillus sp. WF146.Nucleotide binding-promoted conformational changes release a nonnative polypeptide from the Escherichia coli chaperonin GroEL.Expression of recombinant Plasmodium falciparum subtilisin-like protease-1 in insect cells. Characterization, comparison with the parasite protease, and homology modeling.
P2860
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P2860
The prosegment-subtilisin BPN' complex: crystal structure of a specific 'foldase'
description
1995 nî lūn-bûn
@nan
1995 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
The prosegment-subtilisin BPN' complex: crystal structure of a specific 'foldase'
@ast
The prosegment-subtilisin BPN' complex: crystal structure of a specific 'foldase'
@en
The prosegment-subtilisin BPN' complex: crystal structure of a specific 'foldase'
@nl
type
label
The prosegment-subtilisin BPN' complex: crystal structure of a specific 'foldase'
@ast
The prosegment-subtilisin BPN' complex: crystal structure of a specific 'foldase'
@en
The prosegment-subtilisin BPN' complex: crystal structure of a specific 'foldase'
@nl
prefLabel
The prosegment-subtilisin BPN' complex: crystal structure of a specific 'foldase'
@ast
The prosegment-subtilisin BPN' complex: crystal structure of a specific 'foldase'
@en
The prosegment-subtilisin BPN' complex: crystal structure of a specific 'foldase'
@nl
P2093
P1433
P1476
The prosegment-subtilisin BPN' complex: crystal structure of a specific 'foldase'
@en
P2093
P304
P356
10.1016/S0969-2126(01)00225-8
P577
1995-09-15T00:00:00Z