Autocatalytic activation of the furin zymogen requires removal of the emerging enzyme's N-terminus from the active site.

Autocatalytic activation of the furin zymogen requires removal of the emerging enzyme's N-terminus from the active site.

Item
http://www.wikidata.org/entity/Q33427861
Autoactivation of Thrombin PrecursorsStructural and functional diversity of metalloproteinases encoded by theBacteroides fragilispathogenicity islandProbing of exosites leads to novel inhibitor scaffolds of HCV NS3/4A proteinaseNew details of HCV NS3/4A proteinase functionality revealed by a high-throughput cleavage assayBiochemical reconstitution of hemorrhagic-fever arenavirus envelope glycoprotein-mediated membrane fusionCharacterization of the Zika virus two-component NS2B-NS3 protease and structure-assisted identification of allosteric small-molecule antagonists.A novel enediynyl peptide inhibitor of furin that blocks processing of proPDGF-A, B and proVEGF-C.A femtomol range FRET biosensor reports exceedingly low levels of cell surface furin: implications for the processing of anthrax protective antigenVirtual ligand screening of the National Cancer Institute (NCI) compound library leads to the allosteric inhibitory scaffolds of the West Nile Virus NS3 proteinase.An atypical proprotein convertase in Giardia lamblia differentiation.High-resolution analysis and functional mapping of cleavage sites and substrate proteins of furin in the human proteome.Kinetic dissection of the pre-existing conformational equilibrium in the trypsin fold.Histone H4 promotes prothrombin autoactivation.Inflammatory proprotein convertase-matrix metalloproteinase proteolytic pathway in antigen-presenting cells as a step to autoimmune multiple sclerosis.A furin inhibitor downregulates osteosarcoma cell migration by downregulating the expression levels of MT1-MMP via the Wnt signaling pathway.Selective and potent furin inhibitors protect cells from anthrax without significant toxicityInterplay between conformational selection and zymogen activation.
P2860

Autocatalytic activation of the furin zymogen requires removal of the emerging enzyme's N-terminus from the active site.

Item
http://www.wikidata.org/entity/Q33427861
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Autocatalytic activation of th ...... terminus from the active site.
@ast
Autocatalytic activation of th ...... terminus from the active site.
@en
type
label
Autocatalytic activation of th ...... terminus from the active site.
@ast
Autocatalytic activation of th ...... terminus from the active site.
@en
prefLabel
Autocatalytic activation of th ...... terminus from the active site.
@ast
Autocatalytic activation of th ...... terminus from the active site.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
Autocatalytic activation of th ...... terminus from the active site.
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0005031
P407
P433
P478
P50
P577
P5875
P698
P921
P932