The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis
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Caspase-3-mediated cleavage of Akt: involvement of non-consensus sites and influence of phosphorylationGeneration of anti-apoptotic presenilin-2 polypeptides by alternative transcription, proteolysis, and caspase-3 cleavageCaspases: the executioners of apoptosisCaspase-1 (interleukin-1beta-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspasesHsp60 accelerates the maturation of pro-caspase-3 by upstream activator proteases during apoptosis.A-kinase-anchoring protein 95 functions as a potential carrier for the nuclear translocation of active caspase 3 through an enzyme-substrate-like association.Caspases: pharmacological manipulation of cell deathCaspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosisTargeted cell killing by reconstituted caspasesA cloning method for caspase substrates that uses the yeast two-hybrid system: cloning of the antiapoptotic gene gelsolinA novel method for evaluation and screening of caspase inhibitory peptides by the amino acid positional fitness scoreFanconi anemia complementation group A cells are hypersensitive to chromium(VI)-induced toxicity.Crystal structure of baculovirus P35: role of a novel reactive site loop in apoptotic caspase inhibitionDimer formation drives the activation of the cell death protease caspase 9Structural basis for the activation of human procaspase-7Crystal structure of caspase-2, apical initiator of the intrinsic apoptotic pathwayCrystal structure of an invertebrate caspaseSubstrate-Induced Conformational Changes Occur in All Cleaved Forms of Caspase-6Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3.In silicoidentification and crystal structure validation of caspase-3 inhibitors without a P1 aspartic acid moietyMolecular insight into the role of the leucine residue on the L2 loop in the catalytic activity of caspases 3 and 7Structural asymmetry of procaspase-7 bound to a specific inhibitorStructure of recombinant human CPP32 in complex with the tetrapeptide acetyl-Asp-Val-Ala-Asp fluoromethyl ketoneCaspases: opening the boxes and interpreting the arrowsCASH, a novel caspase homologue with death effector domainsDentatorubral pallidoluysian atrophy (DRPLA) protein is cleaved by caspase-3 during apoptosisCaspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tractCaspase-14 is a novel developmentally regulated proteaseWD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activationThioredoxin catalyzes the S-nitrosation of the caspase-3 active site cysteineFas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signalingInduction of an apoptotic program in cell-free extracts by 2-chloro-2'-deoxyadenosine 5'-triphosphate and cytochrome cSubstrate-driven mapping of the degradome by comparison of sequence logosCharacterization of a novel isoform of caspase-9 that inhibits apoptosisConfinement of caspase-12 proteolytic activity to autoprocessingA combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosisMolecular mechanisms of caspase regulation during apoptosisDiscovery of an allosteric site in the caspases
P2860
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P2860
The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis
description
1996 nî lūn-bûn
@nan
1996 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis
@ast
The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis
@en
The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis
@nl
type
label
The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis
@ast
The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis
@en
The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis
@nl
prefLabel
The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis
@ast
The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis
@en
The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis
@nl
P2093
P2860
P356
P1476
The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis
@en
P2093
D M Rasper
D W Nicholson
E P Peterson
J P Vaillancourt
J W Becker
N A Thornberry
P2860
P304
P356
10.1038/NSB0796-619
P577
1996-07-01T00:00:00Z