The three-dimensional structure of mammalian ribonucleotide reductase protein R2 reveals a more-accessible iron-radical site than Escherichia coli R2
about
Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like familyStructure of the yeast ribonucleotide reductase Y2Y4 heterodimerCobalt substitution of mouse R2 ribonucleotide reductase as a model for the reactive diferrous state: spectroscopic and structural evidence for a ferromagnetically coupled dinuclear cobalt clusterAzide and acetate complexes plus two iron-depleted crystal structures of the di-iron enzyme delta9 stearoyl-acyl carrier protein desaturase. Implications for oxygen activation and catalytic intermediates2.6 Å X-ray Crystal Structure of Human p53R2, a p53-Inducible Ribonucleotide Reductase,Rnr4p, a novel ribonucleotide reductase small-subunit proteinMammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cellsMouse ribonucleotide reductase R2 protein: a new target for anaphase-promoting complex-Cdh1-mediated proteolysisThe involvement of Arg265 of mouse ribonucleotide reductase R2 protein in proton transfer and catalysisA novel clade of unique eukaryotic ribonucleotide reductase R2 subunits is exclusive to apicomplexan parasitesRibonucleotide reduction in Pseudomonas species: simultaneous presence of active enzymes from different classesThe conserved Lys-95 charged residue cluster is critical for the homodimerization and enzyme activity of human ribonucleotide reductase small subunit M2Mutations in the R2 subunit of ribonucleotide reductase that confer resistance to hydroxyurea.Mechanism-based inhibition of ribonucleotide reductases: new mechanistic considerations and promising biological applications.Why multiple small subunits (Y2 and Y4) for yeast ribonucleotide reductase? Toward understanding the role of Y4.Identification and characterization of alternative promoters, transcripts and protein isoforms of zebrafish R2 gene.Oligopeptide inhibition of class I ribonucleotide reductases.Studies of ribonucleotide reductase in crucian carp-an oxygen dependent enzyme in an anoxia tolerant vertebrate.Structural basis on the dityrosyl-diiron radical cluster and the functional differences of human ribonucleotide reductase small subunits hp53R2 and hRRM2.An active dimanganese(III)-tyrosyl radical cofactor in Escherichia coli class Ib ribonucleotide reductase.Cloning and characterization of the R1 and R2 subunits of ribonucleotide reductase from Trypanosoma brucei.Metallation and mismetallation of iron and manganese proteins in vitro and in vivo: the class I ribonucleotide reductases as a case studyA tyrosine-tryptophan dyad and radical-based charge transfer in a ribonucleotide reductase-inspired maquette.Class I ribonucleotide reductases: metallocofactor assembly and repair in vitro and in vivo.Mechanism of assembly of the dimanganese-tyrosyl radical cofactor of class Ib ribonucleotide reductase: enzymatic generation of superoxide is required for tyrosine oxidation via a Mn(III)Mn(IV) intermediateDirect Measurement of the Radical Translocation Distance in the Class I Ribonucleotide Reductase from Chlamydia trachomatis.EXAFS simulation refinement based on broken-symmetry DFT geometries for the Mn(IV)-Fe(III) center of class I RNR from Chlamydia trachomatis.Density functional theory analysis of structure, energetics, and spectroscopy for the Mn-Fe active site of Chlamydia trachomatis ribonucleotide reductase in four oxidation states.Targeting ribonucleotide reductase for cancer therapy.A new method of identifying the site of tyrosyl radicals in proteins.Effects of radiofrequency radiation on human ferritin: an in vitro enzymun assay.RAGged repair: what's new in V(D)J recombination.Proton Coupled Electron Transfer and Redox Active Tyrosines: Structure and Function of the Tyrosyl Radicals in Ribonucleotide Reductase and Photosystem II.Sequence of a mosquito ribonucleotide reductase cDNA and evidence for gene amplification in hydroxyurea-resistant cells.Mössbauer properties of the diferric cluster and the differential iron(II)-binding affinity of the iron sites in protein R2 of class Ia Escherichia coli ribonucleotide reductase: a DFT/electrostatics study.Structure-function investigation of the interaction of 1- and 2-substituted 3-hydroxypyridin-4-ones with 5-lipoxygenase and ribonucleotide reductase.X-ray reduction correlates with soaking accessibility as judged from four non-crystallographically related diiron sites.Crystal structural studies of changes in the native dinuclear iron center of ribonucleotide reductase protein R2 from mouse.Differential effects of hydroxyurea upon deoxyribonucleoside triphosphate pools, analyzed with vaccinia virus ribonucleotide reductase.Cell proliferation and gill morphology in anoxic crucian carp.
P2860
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P2860
The three-dimensional structure of mammalian ribonucleotide reductase protein R2 reveals a more-accessible iron-radical site than Escherichia coli R2
description
1996 nî lūn-bûn
@nan
1996 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
The three-dimensional structur ...... site than Escherichia coli R2
@ast
The three-dimensional structur ...... site than Escherichia coli R2
@en
The three-dimensional structur ...... site than Escherichia coli R2
@nl
type
label
The three-dimensional structur ...... site than Escherichia coli R2
@ast
The three-dimensional structur ...... site than Escherichia coli R2
@en
The three-dimensional structur ...... site than Escherichia coli R2
@nl
prefLabel
The three-dimensional structur ...... site than Escherichia coli R2
@ast
The three-dimensional structur ...... site than Escherichia coli R2
@en
The three-dimensional structur ...... site than Escherichia coli R2
@nl
P2093
P921
P356
P1476
The three-dimensional structur ...... site than Escherichia coli R2
@en
P2093
B B Nielsen
I K Larsen
L Thelander
M Thelander
S Ramaswamy
P304
P356
10.1006/JMBI.1996.0546
P407
P577
1996-10-11T00:00:00Z