A mechanism for toxin insertion into membranes is suggested by the crystal structure of the channel-forming domain of colicin E1
about
Colicin biologyObstructing toxin pathways by targeted pore blockageTCTP protects from apoptotic cell death by antagonizing bax functionThe crystal structure of the TolB box of colicin A in complex with TolB reveals important differences in the recruitment of the common TolB translocation portal used by group A colicinsCrystal structure of rat Bcl-xL. Implications for the function of the Bcl-2 protein familyDual expression profile of type VI secretion system immunity genes protects pandemic Vibrio cholerae.A structural basis for cellular uptake of GST-fold proteinsTuning the membrane surface potential for efficient toxin import.Computational studies of colicin insertion into membranes: the closed stateThe role of the TolC family in protein transport and multidrug efflux. From stereochemical certainty to mechanistic hypothesis.Structural studies of apoptosis and ion transport regulatory proteins in membranesAcid destabilization of the solution conformation of Bcl-xL does not drive its pH-dependent insertion into membranesTranslocation of the catalytic domain of diphtheria toxin across planar phospholipid bilayers by its own T domainDesign and optimization of peptide nanoparticlesMembrane-bound state of the colicin E1 channel domain as an extended two-dimensional helical array.Identification of channel-lining amino acid residues in the hydrophobic segment of colicin Ia.Oligomeric structure of colicin ia channel in lipid bilayer membranes.TonB or not TonB: is that the question?Translocation trumps receptor binding in colicin entry into Escherichia coli.Emerging understanding of Bcl-2 biology: Implications for neoplastic progression and treatment.Identification of specific residues in colicin E1 involved in immunity protein recognition.Colicin A immunity protein interacts with the hydrophobic helical hairpin of the colicin A channel domain in the Escherichia coli inner membrane.The tip of the hydrophobic hairpin of colicin U is dispensable for colicin U activity but is important for interaction with the immunity protein.Colicin import into Escherichia coli cells.Mutagenic scan of the H-N-H motif of colicin E9: implications for the mechanistic enzymology of colicins, homing enzymes and apoptotic endonucleases.The cytosolic domain of Bcl-2 oligomerizes to form pores in model mitochondrial outer membrane at acidic pH.Channel domain of colicin A modifies the dimeric organization of its immunity protein.Structure in the channel forming domain of colicin E1 bound to membranes: the 402-424 sequence.The Colicin E1 TolC-Binding Conformer: Pillar or Pore Function of TolC in Colicin Import?Estimation of the number of alpha-helical and beta-strand segments in proteins using circular dichroism spectroscopy.Colicin E1 forms a dimer after urea-induced unfolding.Harmonic analysis of the fluorescence response of bimane adducts of colicin E1 at helices 6, 7, and 10.Identification of multiple Caenorhabditis elegans caspases and their potential roles in proteolytic cascades.Tryptophan-dependent sensitized photoinactivation of colicin E1 channels in bilayer lipid membranes.Scanning the membrane-bound conformation of helix 1 in the colicin E1 channel domain by site-directed fluorescence labeling.Protein-fluctuation-induced water-pore formation in ion channel voltage-sensor translocation across a lipid bilayer membrane.Electroinsertion and activation of the C-terminal domain of colicin A, a voltage gated bacterial toxin, into mammalian cell membranes.Lipid-destabilizing properties of the hydrophobic helices H8 and H9 from colicin E1.The molecular basis for the pH-activation mechanism in the channel-forming bacterial colicin E1.Pathways of colicin import: utilization of BtuB, OmpF porin and the TolC drug-export protein.
P2860
Q24671701-42EB94A0-2159-49E8-97FC-D240DBC467ACQ26827489-1FCBF3CE-C338-43CD-B306-450B2FCE0563Q27649850-C9C054E5-1464-4962-907F-DB8D68E8009FQ27656662-E9BE26FA-73C4-43F3-96B8-5F6FC5438215Q27746503-D5499FE8-D0D5-48A1-9DB7-08BC3D4B1CD4Q30356972-E5AB9B87-D4C1-44E4-BC60-6588E79A379AQ31004655-74B0518D-1523-4571-A9DC-4187E8D6B0E3Q34065539-A03DDFC3-A680-4192-8B5E-5309181D0174Q34372578-5236D000-0636-4244-B7C6-59381AEDE98BQ34394110-D3B1E14F-E24E-43DA-88C5-C9E9AAE0DF1FQ34549560-05FB423B-1072-4B77-A47D-C766CD5E6FB0Q35546762-14BD25B0-B650-4468-AC9B-7C3869774E4BQ35550977-2B92AED3-B853-4E8C-9670-37024E8E68B4Q36203154-BD8110DC-927E-463E-BEFD-3A05DCDFE8ADQ36469673-18FC9B7A-A9AF-4B5B-AB9D-33F676AFA2B8Q36980023-8D7477D5-691D-4E2D-9251-7964938CBD20Q37269237-03A93763-E220-4515-BB2F-2E7DB17E7579Q37860145-868F8F9A-6F45-4941-91FE-46BC45504C1EQ38061999-1DE561B6-5636-45F4-8A36-1C237B6124CDQ38398064-448D6975-2EC1-4BFF-8A14-6491730BD7B6Q39503094-E676C312-06D2-45E7-B1E7-14930655F118Q39505297-63FF0D7B-BE0A-4D00-887B-C06D903FF3E7Q39567153-EE2E4E8B-427E-4531-902B-739998C53C17Q39567863-E801E17A-99FE-46A3-B28A-14C7DAD054BDQ39681869-AC2281E8-80D0-480A-B8D7-6A207EB3B714Q39780166-7EEA84A1-564F-46E1-BF6A-9341BDF03844Q41501857-F733BFCE-B3CF-4098-8B28-6266C545884EQ41616099-ED4F8FFD-9B34-4BEA-8633-E3FCFB89AE71Q41753242-3FBB4AD3-0957-4FEB-BCD1-3B8E3D110CB2Q42084653-F79EE8E8-E178-4383-BF4E-F906BBFD7B0CQ42993774-377C2940-D114-4270-8670-B4A31BFF6C5FQ43244821-880858DB-3343-4FA7-BF21-DD334AC8F90FQ43531090-5F52F934-F254-4378-BA40-8E0C1E821CA7Q43737379-4D6A20D4-73D5-4EF0-B077-3E544FBDD30FQ46813471-91B78611-2609-47A2-A7C9-21A5ED9EBF66Q50237585-31B56740-80BD-494A-ADCC-0533E579A85DQ51823853-2D0CA23E-BA6C-4DD1-B3D7-F6193D9C96D4Q51907521-BAE3CB93-21D8-4AB4-BBC2-564301F110B3Q52550317-D18A6EAF-5F74-422D-9718-366EEAD389DDQ54322880-1D204189-489C-4105-8CCE-CDA4490772C5
P2860
A mechanism for toxin insertion into membranes is suggested by the crystal structure of the channel-forming domain of colicin E1
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
A mechanism for toxin insertio ...... l-forming domain of colicin E1
@ast
A mechanism for toxin insertio ...... l-forming domain of colicin E1
@en
A mechanism for toxin insertio ...... l-forming domain of colicin E1
@nl
type
label
A mechanism for toxin insertio ...... l-forming domain of colicin E1
@ast
A mechanism for toxin insertio ...... l-forming domain of colicin E1
@en
A mechanism for toxin insertio ...... l-forming domain of colicin E1
@nl
prefLabel
A mechanism for toxin insertio ...... l-forming domain of colicin E1
@ast
A mechanism for toxin insertio ...... l-forming domain of colicin E1
@en
A mechanism for toxin insertio ...... l-forming domain of colicin E1
@nl
P2093
P1433
P1476
A mechanism for toxin insertio ...... l-forming domain of colicin E1
@en
P2093
C V Stauffacher
W A Cramer
P304
P356
10.1016/S0969-2126(97)00200-1
P577
1997-03-15T00:00:00Z