Molecular basis of agonism and antagonism in the oestrogen receptor
about
3D models of MBP, a biologically active metabolite of bisphenol A, in human estrogen receptor α and estrogen receptor βMolecular determinants of the estrogen receptor-coactivator interfaceAn estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogensReceptor interacting protein RIP140 inhibits both positive and negative gene regulation by glucocorticoidsA nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivoBCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cellsCIA, a novel estrogen receptor coactivator with a bifunctional nuclear receptor interacting determinantPeptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor α target gene activationERAP140, a conserved tissue-specific nuclear receptor coactivator.Suppression of estrogen receptor-mediated transcription and cell growth by interaction with TR2 orphan receptorA proline to glycine mutation in the Lck SH3-domain affects conformational sampling and increases ligand binding affinityThyroxine-thyroid hormone receptor interactionsZNF366 is an estrogen receptor corepressor that acts through CtBP and histone deacetylasesIdentification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptorPKA-induced resistance to tamoxifen is associated with an altered orientation of ERalpha towards co-activator SRC-1Splice isoform estrogen receptors as integral transmembrane proteinsIsoforms of steroid receptor co-activator 1 differ in their ability to potentiate transcription by the oestrogen receptorRsk2 allosterically activates estrogen receptor alpha by docking to the hormone-binding domain.Cross-talk between glucocorticoid and retinoic acid signals involving glucocorticoid receptor interaction with the homoeodomain protein Pbx1X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation.Structure and function of steroid receptor AF1 transactivation domains: induction of active conformationsLigand-specific allosteric regulation of coactivator functions of androgen receptor in prostate cancer cellsElectrostatic modulation in steroid receptor recruitment of LXXLL and FXXLF motifsAcetylation of nuclear hormone receptor-interacting protein RIP140 regulates binding of the transcriptional corepressor CtBPGlucocorticoid receptor homodimers and glucocorticoid-mineralocorticoid receptor heterodimers form in the cytoplasm through alternative dimerization interfacesThe xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CARThe orphan nuclear receptor SHP utilizes conserved LXXLL-related motifs for interactions with ligand-activated estrogen receptorsRole for Hsp90-associated cochaperone p23 in estrogen receptor signal transductionCharacterization of the DNA-binding and dimerization properties of the nuclear orphan receptor germ cell nuclear factorSingle-chain estrogen receptors (ERs) reveal that the ERalpha/beta heterodimer emulates functions of the ERalpha dimer in genomic estrogen signaling pathwaysLigand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1The p23 molecular chaperones act at a late step in intracellular receptor action to differentially affect ligand efficaciesThe structure of the ultraspiracle ligand-binding domain reveals a nuclear receptor locked in an inactive conformationEstradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and betaDifferential estradiol and selective estrogen receptor modulator (SERM) regulation of Keratin 13 gene expression and its underlying mechanism in breast cancer cellsDirect visualization of the human estrogen receptor alpha reveals a role for ligand in the nuclear distribution of the receptorSelective androgen receptor modulators in preclinical and clinical developmentIdentification of a third distinct estrogen receptor and reclassification of estrogen receptors in teleostsSelective estrogen receptor modulator (SERM) for the treatment of osteoporosis in postmenopausal women: focus on lasofoxifeneIdentification of xenoestrogens in food additives by an integrated in silico and in vitro approach
P2860
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P2860
Molecular basis of agonism and antagonism in the oestrogen receptor
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
name
Molecular basis of agonism and antagonism in the oestrogen receptor
@ast
Molecular basis of agonism and antagonism in the oestrogen receptor
@en
Molecular basis of agonism and antagonism in the oestrogen receptor
@nl
type
label
Molecular basis of agonism and antagonism in the oestrogen receptor
@ast
Molecular basis of agonism and antagonism in the oestrogen receptor
@en
Molecular basis of agonism and antagonism in the oestrogen receptor
@nl
prefLabel
Molecular basis of agonism and antagonism in the oestrogen receptor
@ast
Molecular basis of agonism and antagonism in the oestrogen receptor
@en
Molecular basis of agonism and antagonism in the oestrogen receptor
@nl
P2093
P3181
P356
P1433
P1476
Molecular basis of agonism and antagonism in the oestrogen receptor
@en
P2093
Brzozowski AM
Carlquist M
Engström O
Gustafsson JA
Hubbard RE
P2888
P304
P3181
P356
10.1038/39645
P407
P50
P577
1997-10-01T00:00:00Z
P5875
P6179
1020755542