Structural basis of pH-dependent antibody binding by the neonatal Fc receptor
about
MHC class I-related neonatal Fc receptor for IgG is functionally expressed in monocytes, intestinal macrophages, and dendritic cellsFunctional reconstitution of human FcRn in Madin-Darby canine kidney cells requires co-expressed human beta 2-microglobulinTRIM21: a cytosolic Fc receptor with broad antibody isotype specificityFc-fusion proteins and FcRn: structural insights for longer-lasting and more effective therapeuticsIgG placental transfer in healthy and pathological pregnanciesUnraveling the Interaction between FcRn and Albumin: Opportunities for Design of Albumin-Based TherapeuticsX-ray Crystal Structures of Monomeric and Dimeric Peptide Inhibitors in Complex with the Human Neonatal Fc Receptor, FcRnStructural Insights into Neonatal Fc Receptor-based Recycling MechanismsTryptophan- and dileucine-based endocytosis signals in the neonatal Fc receptor.Quantitative cumulative biodistribution of antibodies in mice: effect of modulating binding affinity to the neonatal Fc receptorBidirectional FcRn-dependent IgG transport in a polarized human intestinal epithelial cell lineNeonatal Fc receptor: from immunity to therapeuticsDesign of pH sensitive binding proteins from the hyperthermophilic Sso7d scaffoldClinical ramifications of the MHC family Fc receptor FcRn.Bovine FcRn-mediated human immunoglobulin G transfer across the milk-blood barrier in transgenic mice.Investigating the interaction between the neonatal Fc receptor and monoclonal antibody variants by hydrogen/deuterium exchange mass spectrometryStructure of FcRY, an avian immunoglobulin receptor related to mammalian mannose receptors, and its complex with IgY.FcRn: The Architect Behind the Immune and Nonimmune Functions of IgG and Albumin.Immunization of pregnant women: Future of early infant protection.Intracellular pH sensors: design principles and functional significance.Mechanism of increased clearance of glycated albumin by proximal tubule cells.Maternal Human Immunodeficiency Virus-Associated Hypergammaglobulinemia Reduces Transplacental Transfer of Immunoglobulin G to Plasmodium falciparum Antigens in Cameroonian Neonates.N-Glycan Moieties in Neonatal Fc Receptor Determine Steady-state Membrane Distribution and Directional Transport of IgG.Analytical FcRn affinity chromatography for functional characterization of monoclonal antibodies.Tumor-directed immunotherapy can generate tumor-specific T cell responses through localized co-stimulationChimeric anti-CD14 IGG2/4 Hybrid antibodies for therapeutic intervention in pig and human models of inflammation.Binding structures and energies of the human neonatal Fc receptor with human Fc and its mutants by molecular modeling and dynamics simulations.Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential.Monoclonal antibody clearance. Impact of modulating the interaction of IgG with the neonatal Fc receptor.Characterization of the porcine neonatal Fc receptor--potential use for trans-epithelial protein delivery.Recognition of the tryptophan-based endocytosis signal in the neonatal Fc Receptor by the mu subunit of adaptor protein-2.Fusion of the mouse IgG1 Fc domain to the VHH fragment (ARP1) enhances protection in a mouse model of rotavirus.Conformational Destabilization of Immunoglobulin G Increases the Low pH Binding Affinity with the Neonatal Fc Receptor.Application of human FcRn transgenic mice as a pharmacokinetic screening tool of monoclonal antibody.An antibody with Fab-constant domains exchanged for a pair of CH3 domains.
P2860
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P2860
Structural basis of pH-dependent antibody binding by the neonatal Fc receptor
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
name
Structural basis of pH-dependent antibody binding by the neonatal Fc receptor
@ast
Structural basis of pH-dependent antibody binding by the neonatal Fc receptor
@en
Structural basis of pH-dependent antibody binding by the neonatal Fc receptor
@nl
type
label
Structural basis of pH-dependent antibody binding by the neonatal Fc receptor
@ast
Structural basis of pH-dependent antibody binding by the neonatal Fc receptor
@en
Structural basis of pH-dependent antibody binding by the neonatal Fc receptor
@nl
prefLabel
Structural basis of pH-dependent antibody binding by the neonatal Fc receptor
@ast
Structural basis of pH-dependent antibody binding by the neonatal Fc receptor
@en
Structural basis of pH-dependent antibody binding by the neonatal Fc receptor
@nl
P3181
P1433
P1476
Structural basis of pH-dependent antibody binding by the neonatal Fc receptor
@en
P2093
D E Vaughn
P J Bjorkman
P3181
P356
10.1016/S0969-2126(98)00008-2
P577
1998-01-15T00:00:00Z