Structural basis for chemical inhibition of human blood coagulation factor Xa - Wikidata - awgldk - TriplyDB

Structural basis for chemical inhibition of human blood coagulation factor Xa

Structural basis for chemical inhibition of human blood coagulation factor Xa

http://www.wikidata.org/entity/Q27758367

about

Structure of human factor VIIa and its implications for the triggering of blood coagulation Crystal structure of an anticoagulant protein in complex with the Gla domain of factor X Skeletal muscle-specific calpain is an intracellular Na+-dependent protease Homology modelling of transferrin-binding protein A from Neisseria meningitidis.Approaches to selective peptidic inhibitors of factor Xa.Functional and structural characterization of factor Xa dimer in solution.Small, noncovalent serine protease inhibitors.Structure and dynamics of zymogen human blood coagulation factor X Protein pharmacophore selection using hydration-site analysis.Modeling of human factor Va inactivation by activated protein C.Role of the active-site solvent in the thermodynamics of factor Xa ligand binding.Identification of 31 novel mutations in the F8 gene in Spanish hemophilia A patients: structural analysis of 20 missense mutations suggests new intermolecular binding sites.Computational study of the putative active form of protein Z (PZa): sequence design and structural modeling.Molecular dynamics simulations of Factor Xa: insight into conformational transition of its binding subsites.Developments in factor Xa inhibitors for the treatment of thromboembolic disorders.The N-terminal epidermal growth factor-like domain of coagulation factor IX. Probing its functions in the activation of factor IX and factor X with a monoclonal antibody.Molecular determinants of the mechanism underlying acceleration of the interaction between antithrombin and factor Xa by heparin pentasaccharide.Quantitative Correlation of Conformational Binding Enthalpy with Substrate Specificity of Serine Proteases.Alginate/Poly(γ-glutamic Acid) Base Biocompatible Gel for Bone Tissue Engineering.Protein-Templated Formation of an Inhibitor of the Blood Coagulation Factor Xa through a Background-Free Amidation Reaction.Role of orally available antagonists of factor Xa in the treatment and prevention of thromboembolic disease: focus on rivaroxaban.Localization of phosphatidylserine binding sites to structural domains of factor Xa.Structural glycobiology of heparin dynamics on the exosite 2 of coagulation cascade proteases: Implications for glycosaminoglycans antithrombotic activity.Role of the gamma-carboxyglutamic acid domain of activated factor X in the presence of calcium during inhibition by antithrombin-heparin.Gene mutations and three-dimensional structural analysis in 13 families with severe factor X deficiency.Lipid specificity of the membrane binding domain of coagulation factor X.

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P2860

Structural basis for chemical inhibition of human blood coagulation factor Xa

http://www.wikidata.org/entity/Q27758367

description

1998 nî lūn-bûn

@nan

1998 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի հունիսին հրատարակված գիտական հոդված

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1998年の論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年论文

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name

Structural basis for chemical inhibition of human blood coagulation factor Xa

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Structural basis for chemical inhibition of human blood coagulation factor Xa

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Structural basis for chemical inhibition of human blood coagulation factor Xa

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type

label

Structural basis for chemical inhibition of human blood coagulation factor Xa

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Structural basis for chemical inhibition of human blood coagulation factor Xa

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Structural basis for chemical inhibition of human blood coagulation factor Xa

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prefLabel

Structural basis for chemical inhibition of human blood coagulation factor Xa

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Structural basis for chemical inhibition of human blood coagulation factor Xa

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Structural basis for chemical inhibition of human blood coagulation factor Xa

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Structural basis for chemical inhibition of human blood coagulation factor Xa

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P2093

H Kawamoto

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T Honma

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P2860

X-ray structure of clotting factor IXa: active site and module structure related to Xase activity and hemophilia B

Improved methods for building protein models in electron density maps and the location of errors in these models

Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors

Crystal structure of a peptidyl pyridinium methyl ketone inhibitor with thrombin

Crystal structure of human alpha-thrombin complexed with hirugen and p-amidinophenylpyruvate at 1.6 A resolution

Structure of human des(1-45) factor Xa at 2.2 A resolution

The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor

The relative orientation of Gla and EGF domains in coagulation factor X is altered by Ca2+ binding to the first EGF domain. A combined NMR-small angle X-ray scattering study

Enzyme flexibility, solvent and 'weak' interactions characterize thrombin-ligand interactions: implications for drug design

X-ray structure of active site-inhibited clotting factor Xa. Implications for drug design and substrate recognition

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scholarly article

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