Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.
about
Tomosyn inhibits synaptic vesicle priming in Caenorhabditis elegansSecretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4Golgi-bound Rab34 is a novel member of the secretory pathwayFbxo45, a novel ubiquitin ligase, regulates synaptic activityRare structural variation of synapse and neurotransmission genes in autismCast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter releaseCrystal structure of the Habc domain of neuronal syntaxin from the squid Loligo pealei reveals conformational plasticity at its C-terminusSynaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic VesiclesThe active zone protein family ELKS supports Ca2+ influx at nerve terminals of inhibitory hippocampal neuronsSynaptotagmin-1 and synaptotagmin-7 trigger synchronous and asynchronous phases of neurotransmitter releaseNeurotransmitter release: the last millisecond in the life of a synaptic vesicleThe presynaptic active zone protein RIM1alpha is critical for normal learning and memory.The presynaptic active zoneSynaptic vesicle exocytosisRIM determines Ca²+ channel density and vesicle docking at the presynaptic active zoneMunc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosisRIM proteins activate vesicle priming by reversing autoinhibitory homodimerization of Munc13ELKS2alpha/CAST deletion selectively increases neurotransmitter release at inhibitory synapsesCrystal structure of the RIM1alpha C2B domain at 1.7 A resolutionAlpha-latrotoxin stimulates a novel pathway of Ca2+-dependent synaptic exocytosis independent of the classical synaptic fusion machineryMunc18-1 binds directly to the neuronal SNARE complexA Munc13/RIM/Rab3 tripartite complex: from priming to plasticity?Molecular mechanisms driving homeostatic plasticity of neurotransmitter releaseFine structure of synapses on dendritic spinesDistinct initial SNARE configurations underlying the diversity of exocytosismiR-153 regulates SNAP-25, synaptic transmission, and neuronal developmentRIC-7 promotes neuropeptide secretionModular architecture of Munc13/calmodulin complexes: dual regulation by Ca2+ and possible function in short-term synaptic plasticityThe Crystal Structure of a Munc13 C-terminal Module Exhibits a Remarkable Similarity to Vesicle Tethering FactorsMso1 is a novel component of the yeast exocytic SNARE complex.Drosophila UNC-13 is essential for synaptic transmissionSynaptotagmin I functions as a calcium regulator of release probabilityThe identification of vesicular glutamate transporter 3 suggests novel modes of signaling by glutamateCAST2: identification and characterization of a protein structurally related to the presynaptic cytomatrix protein CASTInvolvement of protein kinase C in the presynaptic nicotinic modulation of [(3)H]-dopamine release from rat striatal synaptosomesMolecular machines in the synapse: overlapping protein sets control distinct steps in neurosecretionTotal arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle primingJinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosisRab3 GTPase-activating protein regulates synaptic transmission and plasticity through the inactivation of Rab3
P2860
Q21563608-2C099FEC-5DD9-4240-9DC1-5DF5ABCDF2A3Q24293621-F4FF660A-707E-4A0E-B4DE-ABD164D891BCQ24294473-43E2EDE1-631B-42FA-8368-009C8567E5A9Q24336922-51A7F2C9-F4EF-4AFF-958F-904076A543FAQ24608775-A1C8B48E-D50C-4A59-9BD3-50493C31EF50Q24671839-466EC1E4-A2C9-48D8-A731-B3D9266E848DQ24676624-8CC4D93A-7579-4D0E-A029-6127DEC754D7Q24800287-A2A9D9D0-C6BE-44E2-B21D-130AECE942D0Q26269831-F672C53B-6883-4F39-92F3-130BD58A16D9Q26269841-8CD6E68B-64C9-4610-BD1F-6C960983D92AQ26269844-B7F28C5A-51D6-42C2-BA03-44649790A6F2Q26269845-76A6D2C4-985A-4282-BA3A-D42F28CB44F4Q26269858-E50B3BBD-B690-4883-A7A7-9C88F6B1CC5FQ26269863-FCF97F21-0355-448A-9AE5-EE682AAE468AQ26269869-D0CB6D7F-4A0A-45DA-8FDD-C9E93C3472BDQ26269881-95345867-85D3-4C1A-9F7A-CF74E036ADC9Q26269911-EDF04FB2-FE45-4122-BA44-BD23D45DE2ADQ26269920-EBC85216-3DA1-4E0E-9FEB-E8F2B5986900Q26269927-1EFF8D21-1F96-4987-976E-A970AA963271Q26269931-CA762442-5E5B-4270-A0DC-8E37ACBAB15BQ26269933-32BBE188-7F11-4887-878E-272D1F79FA88Q26269949-063B7C25-17B5-494E-8595-6C5A30CABAFDQ26269969-51F7E30B-44BB-48F1-B282-99C8AE270988Q26823427-BA7B3734-9990-4F3A-9D61-12E3BFE9A79CQ26827015-C1EC6D11-5E42-4278-8C41-3731D4D2FC37Q26866150-9696E623-EA2E-48F7-AEC2-B90700E42D18Q27313677-4227DBCB-2C99-4C32-B868-A5BC1B80C339Q27335077-249D8F9F-9D99-44CA-AAD4-B6F834402BC7Q27658657-79847A5E-C059-4598-B102-DD060F35778AQ27675057-59B6727B-5423-4208-99BE-BBEAFA3ADB65Q27935333-CF83F559-6B98-45C9-8E76-15DC7E778641Q28145978-EE4D37A6-25E7-4D96-99AC-7796F68D51F6Q28204147-523E2AB6-7C62-419E-B580-7FBE52EDE0B5Q28208620-973DC925-06B1-4C6E-8D4D-4509F1F08F77Q28238737-8A3BE5EA-2D30-4691-BF11-E32E5E1174C5Q28346506-23A6AE96-39D2-474D-BBE3-71B96C4C9389Q28482128-0D526175-35DE-4240-B060-A480CB804817Q28504670-391D745E-F39F-449C-8B19-C5387C7B900EQ28506181-C13CCF7A-BE10-42CA-9C11-C9F771E2080CQ28510800-04DCD66E-41A6-4B9F-86C1-ED241EA6CF8A
P2860
Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.
@ast
Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.
@en
Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.
@nl
type
label
Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.
@ast
Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.
@en
Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.
@nl
altLabel
Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles
@en
prefLabel
Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.
@ast
Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.
@en
Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.
@nl
P2860
P3181
P356
P1433
P1476
Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.
@en
P2093
P2860
P2888
P304
P3181
P356
10.1038/22768
P407
P577
1999-07-29T00:00:00Z
P6179
1026695680