A conserved cysteine is essential for Pex4p-dependent ubiquitination of the peroxisomal import receptor Pex5p.
about
Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptorPEX5 protein binds monomeric catalase blocking its tetramerization and releases it upon binding the N-terminal domain of PEX14HECT and RING finger families of E3 ubiquitin ligases at a glanceThe ubiquitin-conjugating enzyme (E2) Ube2w ubiquitinates the N terminus of substratesE2 enzymes: more than just middle menPeroxisome biogenesis in mammalian cellsPlant peroxisomes: biogenesis and functionProtein monoubiquitination and polyubiquitination generate structural diversity to control distinct biological processesRecent advances in peroxisomal matrix protein importThe Pex1/Pex6 complex is a heterohexameric AAA+ motor with alternating and highly coordinated subunits.Insights into ubiquitin-conjugating enzyme/ co-activator interactions from the structure of the Pex4p:Pex22p complexA disulphide bond in the E2 enzyme Pex4p modulates ubiquitin-conjugating activityThe predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradationPex2 and pex12 function as protein-ubiquitin ligases in peroxisomal protein import.Distinct ubiquitination cascades act on the peroxisomal targeting signal type 2 co-receptor Pex18p.The cytosolic domain of Pex22p stimulates the Pex4p-dependent ubiquitination of the PTS1-receptor.Ubp15p, a ubiquitin hydrolase associated with the peroxisomal export machinery.Degradation-mediated protein quality control at the inner nuclear membraneAWP1/ZFAND6 functions in Pex5 export by interacting with cys-monoubiquitinated Pex5 and Pex6 AAA ATPaseKLHL12 Promotes Non-Lysine Ubiquitination of the Dopamine Receptors D4.2 and D4.4, but Not of the ADHD-Associated D4.7 VariantUrm1 at the crossroad of modifications. 'Protein Modifications: Beyond the Usual Suspects' Review SeriesProperties of the ubiquitin-pex5p thiol ester conjugate.Cysteine ubiquitination of PTS1 receptor Pex5p regulates Pex5p recycling.Ube2j2 ubiquitinates hydroxylated amino acids on ER-associated degradation substrates.Genome-wide analysis of effectors of peroxisome biogenesis.Serine residues in the cytosolic tail of the T-cell antigen receptor alpha-chain mediate ubiquitination and endoplasmic reticulum-associated degradation of the unassembled protein.A PEX7-centered perspective on the peroxisomal targeting signal type 2-mediated protein import pathway.Complex regulation controls Neurogenin3 proteolysis.Reducing PEX13 expression ameliorates physiological defects of late-acting peroxin mutants.Ubiquitination of mammalian Pex5p, the peroxisomal import receptor.Peroxisome assembly: matrix and membrane protein biogenesis.Ubiquitylation on canonical and non-canonical sites targets the transcription factor neurogenin for ubiquitin-mediated proteolysisThe peroxisomal protein import machinery displays a preference for monomeric substrates.Cysteine-dependent ubiquitination of Pex18p is linked to cargo translocation across the peroxisomal membraneRevisiting the intraperoxisomal pathway of mammalian PEX7.Identification of ubiquitin-specific protease 9X (USP9X) as a deubiquitinase acting on ubiquitin-peroxin 5 (PEX5) thioester conjugate.Ubiquitination of BST-2 protein by HIV-1 Vpu protein does not require lysine, serine, or threonine residues within the BST-2 cytoplasmic domain.Cysteine-specific ubiquitination protects the peroxisomal import receptor Pex5p against proteasomal degradationCovalent Label Transfer between Peroxisomal Importomer Components Reveals Export-driven Import InteractionsUnique requirements for mono- and polyubiquitination of the peroxisomal targeting signal co-receptor, Pex20.
P2860
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P2860
A conserved cysteine is essential for Pex4p-dependent ubiquitination of the peroxisomal import receptor Pex5p.
description
2007 nî lūn-bûn
@nan
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
A conserved cysteine is essent ...... xisomal import receptor Pex5p.
@ast
A conserved cysteine is essent ...... xisomal import receptor Pex5p.
@en
A conserved cysteine is essent ...... xisomal import receptor Pex5p.
@nl
type
label
A conserved cysteine is essent ...... xisomal import receptor Pex5p.
@ast
A conserved cysteine is essent ...... xisomal import receptor Pex5p.
@en
A conserved cysteine is essent ...... xisomal import receptor Pex5p.
@nl
altLabel
A conserved cysteine is essent ...... oxisomal import receptor Pex5p
@en
prefLabel
A conserved cysteine is essent ...... xisomal import receptor Pex5p.
@ast
A conserved cysteine is essent ...... xisomal import receptor Pex5p.
@en
A conserved cysteine is essent ...... xisomal import receptor Pex5p.
@nl
P2860
P3181
P356
P1476
A conserved cysteine is essent ...... xisomal import receptor Pex5p.
@en
P2093
Ben Distel
Marlene van den Berg
P2860
P304
P3181
P356
10.1074/JBC.M702038200
P407
P577
2007-08-03T00:00:00Z