Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation.
about
Retrograde transport pathways utilised by viruses and protein toxinsMammalian Sec61 is associated with Sec62 and Sec63TEB4 is a C4HC3 RING finger-containing ubiquitin ligase of the endoplasmic reticulumHuman HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulumSimultaneous induction of the four subunits of the TRAP complex by ER stress accelerates ER degradationA glycosylated type I membrane protein becomes cytosolic when peptide: N-glycanase is compromised.One step at a time: endoplasmic reticulum-associated degradationProtein folding and quality control in the ERRecent technical developments in the study of ER-associated degradationEndoplasmic reticulum-mediated protein quality control in ArabidopsisThe delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiologyThe protein translocation channel mediates glycopeptide export across the endoplasmic reticulum membraneMolecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation.Endoplasmic Reticulum-associated Degradation of Pca1p, a Polytopic Protein, via Interaction with the Proteasome at the MembraneSec61p is part of the endoplasmic reticulum-associated degradation machineryProtein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48.ERAD and protein import defects in a sec61 mutant lacking ER-lumenal loop 7.The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation.The protein translocation channel binds proteasomes to the endoplasmic reticulum membraneCoordination of N-glycosylation and protein translocation across the endoplasmic reticulum membrane by Sss1 protein.Der3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins.Autoubiquitination of the Hrd1 Ligase Triggers Protein Retrotranslocation in ERAD.Mnl1p, an alpha -mannosidase-like protein in yeast Saccharomyces cerevisiae, is required for endoplasmic reticulum-associated degradation of glycoproteins.Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein.Degradation of misfolded endoplasmic reticulum glycoproteins in Saccharomyces cerevisiae is determined by a specific oligosaccharide structure.Sec61p serves multiple roles in secretory precursor binding and translocation into the endoplasmic reticulum membrane.Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p.Distinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein folding.AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation.Molecular characterization of a novel mammalian DnaJ-like Sec63p homologCleaning up in the endoplasmic reticulum: ubiquitin in chargeERAD: the long road to destructionCalnexin and other factors that alter translocation affect the rapid binding of ubiquitin to apoB in the Sec61 complexUbiquitination is essential for human cytomegalovirus US11-mediated dislocation of MHC class I molecules from the endoplasmic reticulum to the cytosolProteasomes and ubiquitin are involved in the turnover of the wild-type prion proteinSec61p-independent degradation of the tail-anchored ER membrane protein Ubc6pA microsomal GTPase is required for glycopeptide export from the mammalian endoplasmic reticulumA novel type of co-chaperone mediates transmembrane recruitment of DnaK-like chaperones to ribosomesInter-species complementation of the translocon beta subunit requires only its transmembrane domain.Quality control: from molecules to organelles.
P2860
Q21245139-1033B5F8-123D-4B52-B19E-F3A67558C9FFQ22254037-BC46C165-F26C-42F6-B548-63340E899E13Q24292812-B5B73D2F-FF9A-416E-A0A6-CC09A4815CFFQ24298901-BE8C8EB1-1934-4E3F-B2EB-0F35B72CF0A6Q24300776-C72C4A2B-689D-4CEA-9D19-7B7043D1EA58Q24535941-180BE6F0-32DB-4750-A62E-FE9EE8DA045CQ24658302-5E2E062B-0CC1-4392-9367-EC5D73ECB245Q26823157-54F1E5F6-9406-40D0-9A10-24BD7D00F82BQ26823514-33551F11-1DF1-4208-A79A-87C4394A30E5Q26824018-31BA08EC-C9B4-4D32-B4F8-BEBE428D0E99Q27015793-87F946D6-A943-467A-BFC5-5E1D238341B1Q27478172-27845629-049C-4E87-8FAF-01F5BCC67FDDQ27930004-88D1F3BA-071A-4352-8FFA-F4B3DEB40820Q27930456-B217375D-04E6-429C-A2AF-4D39F2710E5AQ27930621-086236DD-D58B-4FDD-9EBE-42022395C61BQ27930706-40509DBB-C8E5-40A6-B0C6-D84A4833E20CQ27931054-41A52EE2-6317-4D9B-B91F-F409062BAE76Q27931326-93983CBD-1844-4F1C-965E-8096ED6142FDQ27931542-BDA7CD2B-7AD5-4415-BE21-A2A8DEF0B352Q27932024-339818F7-EFB6-4829-89AC-9D8DE4BF2885Q27934337-C337C6FD-5412-4B51-A9BC-309A67B87E75Q27935283-69AE22AD-8C2E-476A-8AED-2068BC25B3B3Q27937049-002F0812-BB24-450C-93D6-2EC3494A9266Q27938024-1DE847F9-09A1-4C72-8207-6166F0AB39BAQ27938571-C0DF0423-0753-406D-A279-A2E2CC87E482Q27938591-D9CB03EB-AE2C-472A-B1DF-2E40D5E46016Q27938951-D29BF9E1-964C-4212-AF19-DCD5B2770496Q27939944-9D2534EC-386F-411C-9691-97431FC654C1Q27939982-5923CCC1-DA1F-4EE3-91AE-A622547C30AFQ28146116-ABB31BDD-4A7C-49FD-AE38-1A03B775F3B2Q28237362-BBC084EC-362B-4652-B36B-68B86B804C7AQ28264823-F0265663-1B8B-4995-8FB7-E0FAAEA13E97Q28269183-D1900C60-B322-466F-BF8A-72CF6B6449F2Q28346390-D6E1F8D0-68E2-4569-B055-8009427BC430Q28360418-F7EA6B8F-63DE-4B00-BC14-C8893A84A1DCQ28366803-7AE7741B-7483-4E2F-B660-87510D540B2AQ28581817-A6CA5217-F83B-4996-AACB-C61D26E55566Q28588605-9E9836D1-E119-45C5-A79E-00D2BE3BB60CQ33389821-C9ABAF29-6C17-4E04-9B18-5ECC7039C9FAQ33602882-00AA0B38-A2C7-4FF7-B154-9B39AC3BB5A0
P2860
Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation.
description
1997 nî lūn-bûn
@nan
1997 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Sec61p mediates export of a mi ...... o the cytosol for degradation.
@ast
Sec61p mediates export of a mi ...... o the cytosol for degradation.
@en
Sec61p mediates export of a mi ...... o the cytosol for degradation.
@nl
type
label
Sec61p mediates export of a mi ...... o the cytosol for degradation.
@ast
Sec61p mediates export of a mi ...... o the cytosol for degradation.
@en
Sec61p mediates export of a mi ...... o the cytosol for degradation.
@nl
altLabel
Sec61p mediates export of a mi ...... to the cytosol for degradation
@en
prefLabel
Sec61p mediates export of a mi ...... o the cytosol for degradation.
@ast
Sec61p mediates export of a mi ...... o the cytosol for degradation.
@en
Sec61p mediates export of a mi ...... o the cytosol for degradation.
@nl
P2860
P356
P1433
P1476
Sec61p mediates export of a mi ...... o the cytosol for degradation.
@en
P2093
P2860
P304
P356
10.1093/EMBOJ/16.15.4540
P407
P577
1997-08-01T00:00:00Z