AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation. - Wikidata - awgldk - TriplyDB

AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation.

AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation.

http://www.wikidata.org/entity/Q27939982

about

Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps Origin and evolution of the peroxisomal proteome.Identification of VCP/p97, carboxyl terminus of Hsp70-interacting protein (CHIP), and amphiphysin II interaction partners using membrane-based human proteome arrays A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum Dual role of NRSF/REST in activation and repression of the glucocorticoid response A ubiquitin ligase-associated chaperone holdase maintains polypeptides in soluble states for proteasome degradation SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradation Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains A luminal flavoprotein in endoplasmic reticulum-associated degradation The UBX protein SAKS1 negatively regulates endoplasmic reticulum-associated degradation and p97-dependent degradation Protein disulphide isomerase is required for signal peptide peptidase-mediated protein degradation Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane The tissue-specific Rep8/UBXD6 tethers p97 to the endoplasmic reticulum membrane for degradation of misfolded proteins Direct binding of ubiquitin conjugates by the mammalian p97 adaptor complexes, p47 and Ufd1-Npl4.SVIP is a novel VCP/p97-interacting protein whose expression causes cell vacuolation.Folding-competent and folding-defective forms of ricin A chain have different fates after retrotranslocation from the endoplasmic reticulum Inhibition of p97-dependent protein degradation by Eeyarestatin I Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control Ring of Change: CDC48/p97 Drives Protein Dynamics at Chromatin Impaired Autophagy and Defective Mitochondrial Function: Converging Paths on the Road to Motor Neuron Degeneration Ubiquitylation of an ERAD substrate occurs on multiple types of amino acids Molecular motor proteins and amyotrophic lateral sclerosis Protein folding and quality control in the ER Recent technical developments in the study of ER-associated degradation The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology Structural and mutational studies on the importance of oligosaccharide binding for the activity of yeast PNGase Structure and Function of the N-terminal Nucleolin Binding Domain of Nuclear Valosin-containing Protein-like 2 (NVL2) Harboring a Nucleolar Localization Signal Key steps in ERAD of luminal ER proteins reconstituted with purified components Doa1 is a Cdc48 adapter that possesses a novel ubiquitin binding domain Sec61p is part of the endoplasmic reticulum-associated degradation machinery A Cdc48p-associated factor modulates endoplasmic reticulum-associated degradation, cell stress, and ubiquitinated protein homeostasis The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment A proteasomal ATPase contributes to dislocation of endoplasmic reticulum-associated degradation (ERAD) substrates.Traffic-independent function of the Sar1p/COPII machinery in proteasomal sorting of the cystic fibrosis transmembrane conductance regulator Autoubiquitination of the Hrd1 Ligase Triggers Protein Retrotranslocation in ERAD.Membrane-bound Ubx2 recruits Cdc48 to ubiquitin ligases and their substrates to ensure efficient ER-associated protein degradation.Sel1p/Ubx2p participates in a distinct Cdc48p-dependent endoplasmic reticulum-associated degradation pathway.Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein.Cdc48/p97 mediates UV-dependent turnover of RNA Pol II.

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AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation.

http://www.wikidata.org/entity/Q27939982

description

2002 nî lūn-bûn

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2002 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2002 թվականի հունվարին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

AAA-ATPase p97/Cdc48p, a cytos ...... ssociated protein degradation.

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AAA-ATPase p97/Cdc48p, a cytos ...... ssociated protein degradation.

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AAA-ATPase p97/Cdc48p, a cytos ...... ssociated protein degradation.

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type

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AAA-ATPase p97/Cdc48p, a cytos ...... ssociated protein degradation.

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AAA-ATPase p97/Cdc48p, a cytos ...... ssociated protein degradation.

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AAA-ATPase p97/Cdc48p, a cytos ...... ssociated protein degradation.

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prefLabel

AAA-ATPase p97/Cdc48p, a cytos ...... ssociated protein degradation.

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AAA-ATPase p97/Cdc48p, a cytos ...... ssociated protein degradation.

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AAA-ATPase p97/Cdc48p, a cytos ...... ssociated protein degradation.

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MCB.22.2.626-634.2002

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Molecular and Cellular Biology

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AAA-ATPase p97/Cdc48p, a cytos ...... ssociated protein degradation.

@en

P2093

Anat Kerem

http://www.w3.org/2001/XMLSchema#string

Efrat Rabinovich

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Kai-Uwe Fröhlich

http://www.w3.org/2001/XMLSchema#string

Noam Diamant

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Shoshana Bar-Nun

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P2860

Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin-proteasome degradation

Involvement of valosin-containing protein, an ATPase Co-purified with IkappaBalpha and 26 S proteasome, in ubiquitin-proteasome-mediated degradation of IkappaBalpha

Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome

A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways

Tyrosine phosphorylation of p97 regulates transitional endoplasmic reticulum assembly in vitro

Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation.

Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation.

A regulatory link between ER-associated protein degradation and the unfolded-protein response.

Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation.

The engagement of Sec61p in the ER dislocation process.

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626-34

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scholarly article

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1891530

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10.1128/MCB.22.2.626-634.2002

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P433

2

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22

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2002-01-01T00:00:00Z

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11756557

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P921

molecular chaperones

endoplasmic reticulum

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139744

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