The DExD/H-box ATPase Prp2p destabilizes and proofreads the catalytic RNA core of the spliceosome.
about
The organization and contribution of helicases to RNA splicingNew Perspectives on DNA and RNA Triplexes As Effectors of Biological ActivityFunctional roles of DExD/H-box RNA helicases in Pre-mRNA splicingRNA-Binding Proteins: Splicing Factors and DiseaseMolecular architecture of the Saccharomyces cerevisiae activated spliceosomeDynamic Contacts of U2, RES, Cwc25, Prp8 and Prp45 Proteins with the Pre-mRNA Branch-Site and 3' Splice Site during Catalytic Activation and Step 1 Catalysis in Yeast Spliceosomes.The G-patch protein Spp2 couples the spliceosome-stimulated ATPase activity of the DEAH-box protein Prp2 to catalytic activation of the spliceosomeSF3b1 mutations associated with myelodysplastic syndromes alter the fidelity of branchsite selection in yeastEvidence for a group II intron-like catalytic triplex in the spliceosomeSingle molecule analysis reveals reversible and irreversible steps during spliceosome activationSpliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice Sites.Yeast Prp2 liberates the 5' splice site and the branch site adenosine for catalysis of pre-mRNA splicing.Structural toggle in the RNaseH domain of Prp8 helps balance splicing fidelity and catalytic efficiency.Lights, camera, action! Capturing the spliceosome and pre-mRNA splicing with single-molecule fluorescence microscopy.Functions and regulation of the Brr2 RNA helicase during splicing.The NineTeen Complex (NTC) and NTC-associated proteins as targets for spliceosomal ATPase action during pre-mRNA splicing.Remodeling of U2-U6 snRNA helix I during pre-mRNA splicing by Prp16 and the NineTeen Complex protein Cwc2Cryo-electron microscopy snapshots of the spliceosome: structural insights into a dynamic ribonucleoprotein machine.Stress-induced Pseudouridylation Alters the Structural Equilibrium of Yeast U2 snRNA Stem II.The RES complex is required for efficient transformation of the precatalytic B spliceosome into an activated Bact complex.Crystal structure of the spliceosomal DEAH-box ATPase Prp2.
P2860
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P2860
The DExD/H-box ATPase Prp2p destabilizes and proofreads the catalytic RNA core of the spliceosome.
description
2014 nî lūn-bûn
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2014 թուականի Մարտին հրատարակուած գիտական յօդուած
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2014 թվականի մարտին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
@yue
2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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name
The DExD/H-box ATPase Prp2p de ...... c RNA core of the spliceosome.
@ast
The DExD/H-box ATPase Prp2p de ...... c RNA core of the spliceosome.
@en
The DExD/H-box ATPase Prp2p de ...... c RNA core of the spliceosome.
@nl
type
label
The DExD/H-box ATPase Prp2p de ...... c RNA core of the spliceosome.
@ast
The DExD/H-box ATPase Prp2p de ...... c RNA core of the spliceosome.
@en
The DExD/H-box ATPase Prp2p de ...... c RNA core of the spliceosome.
@nl
prefLabel
The DExD/H-box ATPase Prp2p de ...... c RNA core of the spliceosome.
@ast
The DExD/H-box ATPase Prp2p de ...... c RNA core of the spliceosome.
@en
The DExD/H-box ATPase Prp2p de ...... c RNA core of the spliceosome.
@nl
P2860
P3181
P356
P1433
P1476
The DExD/H-box ATPase Prp2p de ...... c RNA core of the spliceosome.
@en
P2093
Alissa M Wlodaver
Jonathan P Staley
P2860
P304
P3181
P356
10.1261/RNA.042598.113
P407
P577
2014-03-01T00:00:00Z