Spliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice Sites.
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Cryo-EM structure of the spliceosome immediately after branchingSF3b1 mutations associated with myelodysplastic syndromes alter the fidelity of branchsite selection in yeastUSP39 Deubiquitinase Is Essential for KRAS Oncogene-driven Cancer.What have single-molecule studies taught us about gene expression?SF3B1/Hsh155 HEAT motif mutations affect interaction with the spliceosomal ATPase Prp5, resulting in altered branch site selectivity in pre-mRNA splicingRNA and Proteins: Mutual Respect.Single-Molecule Analysis of Pre-mRNA Splicing with Colocalization Single-Molecule Spectroscopy (CoSMoS).Methodologies for studying the spliceosome's RNA dynamics with single-molecule FRET.The histone variant H2A.Z promotes efficient cotranscriptional splicing in S. cerevisiae.The histone variant H2A.Z promotes splicing of weak introns.Lights, camera, action! Capturing the spliceosome and pre-mRNA splicing with single-molecule fluorescence microscopy.Functions and regulation of the Brr2 RNA helicase during splicing.Human cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion.Genetics and biochemistry remain essential in the structural era of the spliceosome.Structure of a spliceosome remodelled for exon ligation.Structure of the yeast spliceosomal postcatalytic P complex.Functions for fission yeast splicing factors SpSlu7 and SpPrp18 in alternative splice-site choice and stress-specific regulated splicing.Cryo-electron microscopy snapshots of the spliceosome: structural insights into a dynamic ribonucleoprotein machine.Structure of a human catalytic step I spliceosome.Proteins and Proteoforms: New Separation Challenges.Distinct RNA-unwinding mechanisms of DEAD-box and DEAH-box RNA helicase proteins in remodeling structured RNAs and RNPs.Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection.Mechanistic insights into precursor messenger RNA splicing by the spliceosome.Life under the Microscope: Single-Molecule Fluorescence Highlights the RNA World.Synergistic assembly of human pre-spliceosomes across introns and exons.Confirmation of the Role of DHX38 in the Etiology of Early-Onset Retinitis PigmentosaChemical genetic inhibition of DEAD-box proteins using covalent complementarity
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Spliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice Sites.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on February 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Spliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice Sites.
@en
Spliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice Sites.
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type
label
Spliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice Sites.
@en
Spliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice Sites.
@nl
prefLabel
Spliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice Sites.
@en
Spliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice Sites.
@nl
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Spliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice Sites.
@en
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Daniel R Semlow
Jonathan P Staley
Mario R Blanco
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P304
P356
10.1016/J.CELL.2016.01.025
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P577
2016-02-01T00:00:00Z