Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.
about
A comprehensive functional analysis of PTEN mutations: implications in tumor- and autism-related syndromesLethal congenital contractural syndrome type 2 (LCCS2) is caused by a mutation in ERBB3 (Her3), a modulator of the phosphatidylinositol-3-kinase/Akt pathwayNew technologies for 21st century plant scienceA functional dissection of PTEN N-terminus: implications in PTEN subcellular targeting and tumor suppressor activityProtein kinase C-delta mediates neuronal apoptosis in the retinas of diabetic rats via the Akt signaling pathwayHuman protein phosphatase PP6 regulatory subunits provide Sit4-dependent and rapamycin-sensitive sap function in Saccharomyces cerevisiae.Mammalian septins are required for phagosome formation.Stabilization of the actomyosin ring enables spermatocyte cytokinesis in DrosophilaThe emerging functions of septins in metazoansRomidepsin (FK228) and its analogs directly inhibit phosphatidylinositol 3-kinase activity and potently induce apoptosis as histone deacetylase/phosphatidylinositol 3-kinase dual inhibitors.Phosphatidylinositol-4,5-bisphosphate promotes budding yeast septin filament assembly and organization.Septin structure and function in yeast and beyondLangevin dynamics simulations of charged model phosphatidylinositol lipids in the presence of diffusion barriers: toward an atomic level understanding of corralling of PIP2 by protein fences in biological membranes.A generalised enzyme kinetic model for predicting the behaviour of complex biochemical systemsSeptin Form and Function at the Cell CortexLethal contractural syndrome type 3 (LCCS3) is caused by a mutation in PIP5K1C, which encodes PIPKI gamma of the phophatidylinsitol pathway.Cell polarization and cytokinesis in budding yeastSome assembly required: yeast septins provide the instruction manualResistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240.Systems biology of AGC kinases in fungi.Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiaeSuperfluous role of mammalian septins 3 and 5 in neuronal development and synaptic transmission.Septins: molecular partitioning and the generation of cellular asymmetry.Expressing and functional analysis of mammalian apoptotic regulators in yeast.Exploring Missense Mutations in Tyrosine Kinases Implicated with Neurodegeneration.Enhanced 5-fluorouracil cytotoxicity in high COX-2 expressing hepatocellular carcinoma cells by wogonin via the PI3K/Akt pathway.Role of the PTEN/PI3K/VEGF pathway in the development of Kawasaki disease.Discovery of drug-resistant and drug-sensitizing mutations in the oncogenic PI3K isoform p110 alpha.The Salmonella effector SteA binds phosphatidylinositol 4-phosphate for subcellular targeting within host cells.Designing synthetic regulatory networks capable of self-organizing cell polarization.Phosphatidylinositol 3-kinase-dependent activation of mammalian protein kinase B/Akt in Saccharomyces cerevisiae, an in vivo model for the functional study of Akt mutationsInsights into the pathological mechanisms of p85α mutations using a yeast-based phosphatidylinositol 3-kinase modelAn improved Akt reporter reveals intra- and inter-cellular heterogeneity and oscillations in signal transduction.A yeast-based in vivo bioassay to screen for class I phosphatidylinositol 3-kinase specific inhibitors.Structural features of human inositol phosphate multikinase rationalize its inositol phosphate kinase and phosphoinositide 3-kinase activities.Heterologous mammalian Akt disrupts plasma membrane homeostasis by taking over TORC2 signaling in Saccharomyces cerevisiae.Overexpressing TPTE2 (TPIP), a homolog of the human tumor suppressor gene PTEN, rescues the abnormal phenotype of the PTEN-/- mutant.Long-chain n-3 polyunsaturated fatty acids dissociate phosphorylation of Akt from phosphatidylinositol 3′-kinase activity in ratsNeck compartmentalization as the molecular basis for the different endocytic behaviour of Chs3 during budding or hyperpolarized growth in yeast cells
P2860
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P2860
Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.
@ast
Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.
@en
Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.
@nl
type
label
Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.
@ast
Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.
@en
Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.
@nl
prefLabel
Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.
@ast
Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.
@en
Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.
@nl
P2093
P2860
P356
P1433
P1476
Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.
@en
P2093
César Nombela
Françoise M Roelants
Isabel Rodríguez-Escudero
Jeremy Thorner
María Molina
Víctor J Cid
P2860
P304
P356
10.1042/BJ20050574
P407
P577
2005-09-01T00:00:00Z