Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin
about
An overview of Cdk1-controlled targets and processesPR48, a novel regulatory subunit of protein phosphatase 2A, interacts with Cdc6 and modulates DNA replication in human cellsThe human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phaseThe cell cycle regulator p27Kip1 interacts with MCM7, a DNA replication licensing factor, to inhibit initiation of DNA replicationTreslin collaborates with TopBP1 in triggering the initiation of DNA replicationCdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin bindingThe human homolog of Saccharomyces cerevisiae CDC45Xenopus Cdc45-dependent loading of DNA polymerase alpha onto chromatin under the control of S-phase Cdk.Sld3, which interacts with Cdc45 (Sld4), functions for chromosomal DNA replication in Saccharomyces cerevisiaeProcessive DNA helicase activity of the minichromosome maintenance proteins 4, 6, and 7 complex requires forked DNA structuresAssembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinaseBinding of cyclin-dependent kinases to ORC and Cdc6p regulates the chromosome replication cycleInvolvement of human MCM8 in prereplication complex assembly by recruiting hcdc6 to chromatinA requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replicationHuman geminin promotes pre-RC formation and DNA replication by stabilizing CDT1 in mitosisDNA synthesis at individual replication forks requires the essential initiation factor Cdc45pChanges in association of the Xenopus origin recognition complex with chromatin on licensing of replication originsThe replication fork: understanding the eukaryotic replication machinery and the challenges to genome duplicationA double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replicationMultistep regulation of DNA replication by Cdk phosphorylation of HsCdc6Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replicationEasy detection of chromatin binding proteins by the Histone Association Assay.Three wise centromere functions: see no error, hear no break, speak no delayThe mcm5-bob1 bypass of Cdc7p/Dbf4p in DNA replication depends on both Cdk1-independent and Cdk1-dependent steps in Saccharomyces cerevisiae.Cell cycle-dependent phosphorylation of the DNA polymerase epsilon subunit, Dpb2, by the Cdc28 cyclin-dependent protein kinase.Distinct mechanisms control the stability of the related S-phase cyclins Clb5 and Clb6.CLB5 and CLB6 are required for premeiotic DNA replication and activation of the meiotic S/M checkpoint.Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins.Novel role for checkpoint Rad53 protein kinase in the initiation of chromosomal DNA replication in Saccharomyces cerevisiae.Two mcm3 mutations affect different steps in the initiation of DNA replication.Interactions between Mcm10p and other replication factors are required for proper initiation and elongation of chromosomal DNA replication in Saccharomyces cerevisiae.A conserved Hsp10-like domain in Mcm10 is required to stabilize the catalytic subunit of DNA polymerase-alpha in budding yeast.Testing cyclin specificity in the exit from mitosis.The human origin recognition complex protein 1 dissociates from chromatin during S phase in HeLa cellsCentral role for cdc45 in establishing an initiation complex of DNA replication in Xenopus egg extractsInhibition of Mcm4,6,7 helicase activity by phosphorylation with cyclin A/Cdk2Biochemical activities associated with mouse Mcm2 proteinCell cycle-dependent proteolysis and phosphorylation of human Mcm10Pathways governing G1/S transition and their response to DNA damageHuman Dbf4/ASK promoter is activated through the Sp1 and MluI cell-cycle box (MCB) transcription elements
P2860
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P248
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P2860
Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin
description
1998 nî lūn-bûn
@nan
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Formation of a preinitiation c ...... ading of Cdc45p onto chromatin
@ast
Formation of a preinitiation c ...... ading of Cdc45p onto chromatin
@en
Formation of a preinitiation c ...... ading of Cdc45p onto chromatin
@nl
type
label
Formation of a preinitiation c ...... ading of Cdc45p onto chromatin
@ast
Formation of a preinitiation c ...... ading of Cdc45p onto chromatin
@en
Formation of a preinitiation c ...... ading of Cdc45p onto chromatin
@nl
prefLabel
Formation of a preinitiation c ...... ading of Cdc45p onto chromatin
@ast
Formation of a preinitiation c ...... ading of Cdc45p onto chromatin
@en
Formation of a preinitiation c ...... ading of Cdc45p onto chromatin
@nl
P1433
P1476
Formation of a preinitiation c ...... ding of Cdc45p onto chromatin.
@en
P2093
P356
10.1126/SCIENCE.280.5363.593
P407
P577
1998-04-24T00:00:00Z