The HEAT repeat protein Blm10 regulates the yeast proteasome by capping the core particle.
about
Global approaches to understanding ubiquitination.Nuclear Import of Yeast ProteasomesThe Not4 RING E3 Ligase: A Relevant Player in Cotranslational Quality ControlStructural Models for Interactions between the 20S Proteasome and Its PAN/19S ActivatorsStructure of a Blm10 Complex Reveals Common Mechanisms for Proteasome Binding and Gate OpeningBlm10 binds to pre-activated proteasome core particles with open gate conformation.Loss of a 20S proteasome activator in Saccharomyces cerevisiae downregulates genes important for genomic integrity, increases DNA damage, and selectively sensitizes cells to agents with diverse mechanisms of actionThe C-terminal extension of the beta7 subunit and activator complexes stabilize nascent 20 S proteasomes and promote their maturation.Blm10 protein promotes proteasomal substrate turnover by an active gating mechanismAn integrated mass spectrometry-based proteomic approach: quantitative analysis of tandem affinity-purified in vivo cross-linked protein complexes (QTAX) to decipher the 26 S proteasome-interacting network.Acetylation-mediated proteasomal degradation of core histones during DNA repair and spermatogenesis.beta-Subunit appendages promote 20S proteasome assembly by overcoming an Ump1-dependent checkpoint.Blm10 facilitates nuclear import of proteasome core particlesStructural defects in the regulatory particle-core particle interface of the proteasome induce a novel proteasome stress responseBacterial Proteasomes: Mechanistic and Functional InsightsProteasome assemblyAn asymmetric interface between the regulatory and core particles of the proteasomeThe assembly pathway of the 19S regulatory particle of the yeast 26S proteasomeEvolution of proteasome regulators in eukaryotesRegulation of proteasome activity in health and diseaseMycobacterium tuberculosis prcBA genes encode a gated proteasome with broad oligopeptide specificityRecognition and processing of ubiquitin-protein conjugates by the proteasomePR65, the HEAT-repeat scaffold of phosphatase PP2A, is an elastic connector that links force and catalysisSimultaneous fluorescent monitoring of proteasomal subunit catalysisControl of mitochondrial biogenesis and function by the ubiquitin-proteasome systemToward an atomic model of the 26S proteasome.Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiaeAffinity purification of the Arabidopsis 26 S proteasome reveals a diverse array of plant proteolytic complexes.Structure of the Blm10-20 S proteasome complex by cryo-electron microscopy. Insights into the mechanism of activation of mature yeast proteasomes.Regulating the 20S proteasome ubiquitin-independent degradation pathway.Muscle wasting in aged, sarcopenic rats is associated with enhanced activity of the ubiquitin proteasome pathway.Proteasome activator PA200 is required for normal spermatogenesis.Proteasomal degradation of Sfp1 contributes to the repression of ribosome biogenesis during starvation and is mediated by the proteasome activator Blm10.Nuclear transport of yeast proteasomes.Functions of the proteasome on chromatin.A conserved 20S proteasome assembly factor requires a C-terminal HbYX motif for proteasomal precursor bindingNot4 E3 ligase contributes to proteasome assembly and functional integrity in part through Ecm29MiR-29b replacement inhibits proteasomes and disrupts aggresome+autophagosome formation to enhance the antimyeloma benefit of bortezomib.Maturation of the proteasome core particle induces an affinity switch that controls regulatory particle associationRegulated protein turnover: snapshots of the proteasome in action.
P2860
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P2860
The HEAT repeat protein Blm10 regulates the yeast proteasome by capping the core particle.
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The HEAT repeat protein Blm10 ...... by capping the core particle.
@ast
The HEAT repeat protein Blm10 ...... by capping the core particle.
@en
The HEAT repeat protein Blm10 ...... by capping the core particle.
@nl
type
label
The HEAT repeat protein Blm10 ...... by capping the core particle.
@ast
The HEAT repeat protein Blm10 ...... by capping the core particle.
@en
The HEAT repeat protein Blm10 ...... by capping the core particle.
@nl
prefLabel
The HEAT repeat protein Blm10 ...... by capping the core particle.
@ast
The HEAT repeat protein Blm10 ...... by capping the core particle.
@en
The HEAT repeat protein Blm10 ...... by capping the core particle.
@nl
P2093
P2860
P3181
P356
P1476
The HEAT repeat protein Blm10 ...... by capping the core particle.
@en
P2093
Bernat Crosas
Daniel Finley
Marion Schmidt
Patricia G Santamaria
Thomas Walz
Wilhelm Haas
P2860
P2888
P304
P3181
P356
10.1038/NSMB914
P407
P577
2005-04-01T00:00:00Z
P5875
P6179
1050907639