Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis
about
Systematic planning of genome-scale experiments in poorly studied speciesGenome-wide matching of genes to cellular roles using guilt-by-association models derived from single sample analysisMitochondrial targets for pharmacological intervention in human diseaseRespiratory supercomplexes: plasticity and implicationsGMF is a cofilin homolog that binds Arp2/3 complex to stimulate filament debranching and inhibit actin nucleation.The mitochondrial contact site complex, a determinant of mitochondrial architecture.Evolutionary and genetic analyses of mitochondrial translation initiation factors identify the missing mitochondrial IF3 in S. cerevisiae.A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondriaRcf1 and Rcf2, members of the hypoxia-induced gene 1 protein family, are critical components of the mitochondrial cytochrome bc1-cytochrome c oxidase supercomplex.An in silico approach combined with in vivo experiments enables the identification of a new protein whose overexpression can compensate for specific respiratory defects in Saccharomyces cerevisiae.Mzm1 influences a labile pool of mitochondrial zinc important for respiratory functionThe INA complex facilitates assembly of the peripheral stalk of the mitochondrial F1Fo-ATP synthaseThe mitochondrial ADP/ATP carrier associates with the inner membrane presequence translocase in a stoichiometric manner.Experimental Evidence for a Revision in the Annotation of Putative Pyridoxamine 5'-Phosphate Oxidases P(N/M)P from Fungi.Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae.GMF severs actin-Arp2/3 complex branch junctions by a cofilin-like mechanism.Mitochondrial translation initiation machinery: conservation and diversificationMitochondrial Bol1 and Bol3 function as assembly factors for specific iron-sulfur proteins.Aim24 and MICOS modulate respiratory function, tafazzin-related cardiolipin modification and mitochondrial architectureRecent Advances and Emerging Applications in Text and Data Mining for Biomedical DiscoverySlm35 links mitochondrial stress response and longevity through TOR signaling pathwaySimultaneous genome-wide inference of physical, genetic, regulatory, and functional pathway componentsChapter 2: Data-driven view of disease biologyPAR-CLIP data indicate that Nrd1-Nab3-dependent transcription termination regulates expression of hundreds of protein coding genes in yeastAdapting bioinformatics curricula for big data.Implications of Big Data for cell biology.Directing experimental biology: a case study in mitochondrial biogenesis.A computational screen for regulators of oxidative phosphorylation implicates SLIRP in mitochondrial RNA homeostasis.Integrative systems biology for data-driven knowledge discovery.Replicative age induces mitotic recombination in the ribosomal RNA gene cluster of Saccharomyces cerevisiaePILGRM: an interactive data-driven discovery platform for expert biologistsSmall sets of interacting proteins suggest functional linkage mechanisms via Bayesian analogical reasoningRespiratory supercomplexes: structure, function and assembly.Accurate evaluation and analysis of functional genomics data and methods"Guilt by association" is the exception rather than the rule in gene networks.Mitochondrial protein synthesis, import, and assembly.The yeast sphingolipid signaling landscape.Tissue-specific functional networks for prioritizing phenotype and disease genes.Labeling nodes using three degrees of propagationDetermining microbial products and identifying molecular targets in the human microbiome.
P2860
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P2860
Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Computationally driven, quanti ...... d for mitochondrial biogenesis
@ast
Computationally driven, quanti ...... d for mitochondrial biogenesis
@en
Computationally driven, quanti ...... for mitochondrial biogenesis.
@nl
type
label
Computationally driven, quanti ...... d for mitochondrial biogenesis
@ast
Computationally driven, quanti ...... d for mitochondrial biogenesis
@en
Computationally driven, quanti ...... for mitochondrial biogenesis.
@nl
altLabel
Computationally driven, quanti ...... d for mitochondrial biogenesis
@en
prefLabel
Computationally driven, quanti ...... d for mitochondrial biogenesis
@ast
Computationally driven, quanti ...... d for mitochondrial biogenesis
@en
Computationally driven, quanti ...... for mitochondrial biogenesis.
@nl
P2093
P2860
P50
P3181
P1433
P1476
Computationally driven, quanti ...... d for mitochondrial biogenesis
@en
P2093
Alicia P Hayes
Bryan San Luis
Jadine Paw
John J Clore
Michael Costanzo
Rosa M Mendoza
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.1000407
P407
P577
2009-03-01T00:00:00Z