The final stages of spliceosome maturation require Spp2p that can interact with the DEAH box protein Prp2p and promote step 1 of splicing.
about
PRP16, a DEAH-box RNA helicase, is recruited to the spliceosome primarily via its nonconserved N-terminal domainFunctional roles of DExD/H-box RNA helicases in Pre-mRNA splicingRegulation of DEAH/RHA helicases by G-patch proteinsRNA helicases in splicingThe ATPase and helicase activities of Prp43p are stimulated by the G-patch protein Pfa1p during yeast ribosome biogenesis.Spliceosome activation by PRP2 ATPase prior to the first transesterification reaction of pre-mRNA splicingThe DExD/H-box ATPase Prp2p destabilizes and proofreads the catalytic RNA core of the spliceosome.A novel splicing factor, Yju2, is associated with NTC and acts after Prp2 in promoting the first catalytic reaction of pre-mRNA splicing.Identification of eight proteins that cross-link to pre-mRNA in the yeast commitment complexProgression through the spliceosome cycle requires Prp38p function for U4/U6 snRNA dissociationPrp2-mediated protein rearrangements at the catalytic core of the spliceosome as revealed by dcFCCS.Ntr1 activates the Prp43 helicase to trigger release of lariat-intron from the spliceosomeSpliceosome disassembly catalyzed by Prp43 and its associated components Ntr1 and Ntr2.Ntc90 is required for recruiting first step factor Yju2 but not for spliceosome activation.The G-patch protein Spp2 couples the spliceosome-stimulated ATPase activity of the DEAH-box protein Prp2 to catalytic activation of the spliceosomePurification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins.Splicing factor Cwc22 is required for the function of Prp2 and for the spliceosome to escape from a futile pathway.Molecular dissection of step 2 catalysis of yeast pre-mRNA splicing investigated in a purified system.Snt309p, a component of the Prp19p-associated complex that interacts with Prp19p and associates with the spliceosome simultaneously with or immediately after dissociation of U4 in the same manner as Prp19p.Contribution of DEAH-box protein DHX16 in human pre-mRNA splicingThe Escherichia coli DEAD protein DbpA recognizes a small RNA hairpin in 23S rRNA.Malleable ribonucleoprotein machine: protein intrinsic disorder in the Saccharomyces cerevisiae spliceosome.Biased Brownian ratcheting leads to pre-mRNA remodeling and capture prior to first-step splicing.A bird's-eye view of post-translational modifications in the spliceosome and their roles in spliceosome dynamicsCharacterization of purified human Bact spliceosomal complexes reveals compositional and morphological changes during spliceosome activation and first step catalysis.Dominant negative mutants of the yeast splicing factor Prp2 map to a putative cleft region in the helicase domain of DExD/H-box proteins.Definition of a spliceosome interaction domain in yeast Prp2 ATPase.DEAH-box ATPase Prp16 has dual roles in remodeling of the spliceosome in catalytic steps.Structural requirement of Ntc77 for spliceosome activation and first catalytic step.The PRP31 gene encodes a novel protein required for pre-mRNA splicing in Saccharomyces cerevisiae.Six novel genes necessary for pre-mRNA splicing in Saccharomyces cerevisiaeA mutation in a methionine tRNA gene suppresses the prp2-1 Ts mutation and causes a pre-mRNA splicing defect in Saccharomyces cerevisiae.GPKOW is essential for pre-mRNA splicing in vitro and suppresses splicing defect caused by dominant-negative DHX16 mutation in vivo.Dramatically reduced spliceosome in Cyanidioschyzon merolaeGenetic interaction mapping reveals a role for the SWI/SNF nucleosome remodeler in spliceosome activation in fission yeastLimited portability of G-patch domains in regulators of the Prp43 RNA helicase required for pre-mRNA splicing and ribosomal RNA maturation in Saccharomyces cerevisiae.The spliceosome-activating complex: molecular mechanisms underlying the function of a pleiotropic regulatorFunctional roles of protein splicing factors.Dynamic interactions of Ntr1-Ntr2 with Prp43 and with U5 govern the recruitment of Prp43 to mediate spliceosome disassemblyThe interaction of Prp2 with a defined region of the intron is required for the first splicing reaction.
P2860
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P2860
The final stages of spliceosome maturation require Spp2p that can interact with the DEAH box protein Prp2p and promote step 1 of splicing.
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
The final stages of spliceosom ...... nd promote step 1 of splicing.
@ast
The final stages of spliceosom ...... nd promote step 1 of splicing.
@en
The final stages of spliceosom ...... nd promote step 1 of splicing.
@nl
type
label
The final stages of spliceosom ...... nd promote step 1 of splicing.
@ast
The final stages of spliceosom ...... nd promote step 1 of splicing.
@en
The final stages of spliceosom ...... nd promote step 1 of splicing.
@nl
prefLabel
The final stages of spliceosom ...... nd promote step 1 of splicing.
@ast
The final stages of spliceosom ...... nd promote step 1 of splicing.
@en
The final stages of spliceosom ...... nd promote step 1 of splicing.
@nl
P2093
P2860
P3181
P1433
P1476
The final stages of spliceosom ...... nd promote step 1 of splicing.
@en
P2093
P2860
P304
P3181
P407
P577
1995-06-01T00:00:00Z