The yeast SEN1 gene is required for the processing of diverse RNA classes
about
Human senataxin resolves RNA/DNA hybrids formed at transcriptional pause sites to promote Xrn2-dependent terminationSenataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damageBiochemical and genetic evidence for a role of IGHMBP2 in the translational machineryFunctional role for senataxin, defective in ataxia oculomotor apraxia type 2, in transcriptional regulationA SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to sites of transcription-induced DNA damageComparative genomics and evolution of proteins involved in RNA metabolismDisengaging polymerase: terminating RNA polymerase II transcription in budding yeastDExD/H-box RNA helicases in ribosome biogenesisMultiple protein/protein and protein/RNA interactions suggest roles for yeast DNA/RNA helicase Sen1p in transcription, transcription-coupled DNA repair and RNA processing.Dhr1p, a putative DEAH-box RNA helicase, is associated with the box C+D snoRNP U3.Sen1, the yeast homolog of human senataxin, plays a more direct role than Rad26 in transcription coupled DNA repairSen1p contributes to genomic integrity by regulating expression of ribonucleotide reductase 1 (RNR1) in Saccharomyces cerevisiae.Budding yeast RNA polymerases I and II employ parallel mechanisms of transcriptional termination.Mpk1 MAPK association with the Paf1 complex blocks Sen1-mediated premature transcription termination.A well-connected and conserved nucleoplasmic helicase is required for production of box C/D and H/ACA snoRNAs and localization of snoRNP proteins.Senataxin associates with replication forks to protect fork integrity across RNA-polymerase-II-transcribed genes.The Reb1-homologue Ydr026c/Nsi1 is required for efficient RNA polymerase I termination in yeastRNA-binding protein Nrd1 directs poly(A)-independent 3'-end formation of RNA polymerase II transcripts.Formation and nuclear export of tRNA, rRNA and mRNA is regulated by the ubiquitin ligase Rsp5pThe role of the putative 3' end processing endonuclease Ysh1p in mRNA and snoRNA synthesis.Interactions of Sen1, Nrd1, and Nab3 with multiple phosphorylated forms of the Rpb1 C-terminal domain in Saccharomyces cerevisiae.Saccharomyces cerevisiae Sen1 Helicase Domain Exhibits 5'- to 3'-Helicase Activity with a Preference for Translocation on DNA Rather than RNACbf5p, a potential pseudouridine synthase, and Nhp2p, a putative RNA-binding protein, are present together with Gar1p in all H BOX/ACA-motif snoRNPs and constitute a common bipartite structure.Sen1, the homolog of human Senataxin, is critical for cell survival through regulation of redox homeostasis, mitochondrial function, and the TOR pathway in Saccharomyces cerevisiaeTranscription termination by nuclear RNA polymerasesProtein trans-acting factors involved in ribosome biogenesis in Saccharomyces cerevisiaeSenataxin, defective in the neurodegenerative disorder ataxia with oculomotor apraxia 2, lies at the interface of transcription and the DNA damage response.A novel tandem reporter quantifies RNA polymerase II termination in mammalian cellsMechanisms of genome instability induced by RNA-processing defects.A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expressionYeast Sen1 helicase protects the genome from transcription-associated instability.Senataxin, the ortholog of a yeast RNA helicase, is mutant in ataxia-ocular apraxia 2.Genome-wide profiling of yeast DNA:RNA hybrid prone sites with DRIP-chipSmall nucleolar RNAs: versatile trans-acting molecules of ancient evolutionary origin.The small subunit processome in ribosome biogenesis—progress and prospects.Yeast frameshift suppressor mutations in the genes coding for transcription factor Mbf1p and ribosomal protein S3: evidence for autoregulation of S3 synthesisBRCA1 recruitment to transcriptional pause sites is required for R-loop-driven DNA damage repair.Regulation of cell wall biogenesis in Saccharomyces cerevisiae: the cell wall integrity signaling pathway.Emerging Views on the CTD CodeNavigating without a road map
P2860
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P2860
The yeast SEN1 gene is required for the processing of diverse RNA classes
description
1997 nî lūn-bûn
@nan
1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
The yeast SEN1 gene is required for the processing of diverse RNA classes
@ast
The yeast SEN1 gene is required for the processing of diverse RNA classes
@en
The yeast SEN1 gene is required for the processing of diverse RNA classes.
@nl
type
label
The yeast SEN1 gene is required for the processing of diverse RNA classes
@ast
The yeast SEN1 gene is required for the processing of diverse RNA classes
@en
The yeast SEN1 gene is required for the processing of diverse RNA classes.
@nl
prefLabel
The yeast SEN1 gene is required for the processing of diverse RNA classes
@ast
The yeast SEN1 gene is required for the processing of diverse RNA classes
@en
The yeast SEN1 gene is required for the processing of diverse RNA classes.
@nl
P2093
P2860
P3181
P356
P1476
The yeast SEN1 gene is required for the processing of diverse RNA classes
@en
P2093
P2860
P304
P3181
P356
10.1093/NAR/25.23.4778
P407
P577
1997-12-01T00:00:00Z