Carboxyl-terminal isoprenylation of ras-related GTP-binding proteins encoded by rac1, rac2, and ralA
about
The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory functionGeranylgeranyltransferase I inhibitors target RalB to inhibit anchorage-dependent growth and induce apoptosis and RalA to inhibit anchorage-independent growthIdentification of a novel human Rho protein with unusual properties: GTPase deficiency and in vivo farnesylationIdentification of a novel Rac1-interacting protein involved in membrane rufflingPrenyl group identification of rap2 proteins: a ras superfamily member other than ras that is farnesylatedRalA interacts with ZONAB in a cell density-dependent manner and regulates its transcriptional activityRal-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformationCharacterization of the cDNA and genomic sequence of a G protein gamma subunit (gamma 5)Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPasesRal GTPases in tumorigenesis: emerging from the shadowsGeneration and characterization of Rac3 knockout mice.Rac1 controls the subcellular localization of the Rho guanine nucleotide exchange factor Net1A to regulate focal adhesion formation and cell spreadingRalA but not RalB enhances polarized delivery of membrane proteins to the basolateral surface of epithelial cells.CYK-4 regulates Rac, but not Rho, during cytokinesis.Splice variants of SmgGDS control small GTPase prenylation and membrane localizationRequirement for posttranslational processing of Rac GTP-binding proteins for activation of human neutrophil NADPH oxidase.The RalGEF-Ral Effector Signaling Network: The Road Less Traveled for Anti-Ras Drug Discovery.Divergent roles of CAAX motif-signaled posttranslational modifications in the regulation and subcellular localization of Ral GTPases.Matrix compliance regulates Rac1b localization, NADPH oxidase assembly, and epithelial-mesenchymal transition.Regulation of intracellular actin polymerization by prenylated cellular proteins.Selective Rac1 inhibition protects renal tubular epithelial cells from oxalate-induced NADPH oxidase-mediated oxidative cell injury.Posttranslational modification of Ha-ras p21 by farnesyl versus geranylgeranyl isoprenoids is determined by the COOH-terminal amino acidSimvastatin inhibits protein isoprenylation in the brain.Rac-1 superactivation triggers insulin-independent glucose transporter 4 (GLUT4) translocation that bypasses signaling defects exerted by c-Jun N-terminal kinase (JNK)- and ceramide-induced insulin resistance.Alkynyl-farnesol reporters for detection of protein S-prenylation in cells.Purification and identification of FOAD-II, a cytosolic protein that regulates secretion in streptolysin-O permeabilized mast cells, as a rac/rhoGDI complex.Investigation of the effect of the farnesyl protein transferase inhibitor R115777 on isoprenylation and intracellular signalling by the prostacyclin receptor.Isoprenoid metabolism is required for stimulation of the respiratory burst oxidase of HL-60 cells.A shunt pathway limits the CaaX processing of Hsp40 Ydj1p and regulates Ydj1p-dependent phenotypes.A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins.Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton.The effector domain of Rab6, plus a highly hydrophobic C terminus, is required for Golgi apparatus localization.RAL GTPases: Biology and Potential as Therapeutic Targets in Cancer.Expression and translocation of Rac2 in eosinophils during superoxide generation.Distinct CED-10/Rac1 domains confer context-specific functions in development
P2860
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P2860
Carboxyl-terminal isoprenylation of ras-related GTP-binding proteins encoded by rac1, rac2, and ralA
description
1991 nî lūn-bûn
@nan
1991 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Carboxyl-terminal isoprenylati ...... ncoded by rac1, rac2, and ralA
@ast
Carboxyl-terminal isoprenylati ...... ncoded by rac1, rac2, and ralA
@en
Carboxyl-terminal isoprenylati ...... ncoded by rac1, rac2, and ralA
@nl
type
label
Carboxyl-terminal isoprenylati ...... ncoded by rac1, rac2, and ralA
@ast
Carboxyl-terminal isoprenylati ...... ncoded by rac1, rac2, and ralA
@en
Carboxyl-terminal isoprenylati ...... ncoded by rac1, rac2, and ralA
@nl
prefLabel
Carboxyl-terminal isoprenylati ...... ncoded by rac1, rac2, and ralA
@ast
Carboxyl-terminal isoprenylati ...... ncoded by rac1, rac2, and ralA
@en
Carboxyl-terminal isoprenylati ...... ncoded by rac1, rac2, and ralA
@nl
P3181
P1476
Carboxyl-terminal isoprenylati ...... ncoded by rac1, rac2, and ralA
@en
P2093
P304
P3181
P407
P577
1991-05-01T00:00:00Z