Requirement for posttranslational processing of Rac GTP-binding proteins for activation of human neutrophil NADPH oxidase.
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Identification of a conserved Rac-binding site on NADPH oxidases supports a direct GTPase regulatory mechanismThe Role of Rho GTPases in Toxicity of Clostridium difficile ToxinsActivation by Cdc42 and PIP(2) of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp2/3 complexStructural requirements for PAK activation by Rac GTPasesRacF1, a novel member of the Rho protein family in Dictyostelium discoideum, associates transiently with cell contact areas, macropinosomes, and phagosomes.Molecular basis for Rac2 regulation of phagocyte NADPH oxidase.The molecular basis for adhesion-mediated suppression of reactive oxygen species generation by human neutrophilsPseudomonas aeruginosa hemolytic phospholipase C suppresses neutrophil respiratory burst activity.A prenylated p47phox-p67phox-Rac1 chimera is a Quintessential NADPH oxidase activator: membrane association and functional capacity.Assembly of the neutrophil respiratory burst oxidase: a direct interaction between p67PHOX and cytochrome b558.Corequirement of specific phosphoinositides and small GTP-binding protein Cdc42 in inducing actin assembly in Xenopus egg extractsMechanism of Cdc42-induced actin polymerization in neutrophil extractsRegulation of actin polymerization in cell-free systems by GTPgammaS and Cdc42Matrix compliance regulates Rac1b localization, NADPH oxidase assembly, and epithelial-mesenchymal transition.Profilin enhances Cdc42-induced nucleation of actin polymerization.Selective Rac1 inhibition protects renal tubular epithelial cells from oxalate-induced NADPH oxidase-mediated oxidative cell injury.Regulation of NADPH oxidase activity by Rac GTPase activating protein(s).Mechanisms of degranulation in neutrophils.Role of the Rho GTPase Rac in the activation of the phagocyte NADPH oxidase: outsourcing a key task.SmgGDS stabilizes nucleotide-bound and -free forms of the Rac1 GTP-binding protein and stimulates GTP/GDP exchange through a substituted enzyme mechanismIdentification of three subunits of the high affinity omega-conotoxin MVIIC-sensitive Ca2+ channel.Induction of exocytosis from permeabilized mast cells by the guanosine triphosphatases Rac and Cdc42.Staphylococcus aureus, phagocyte NADPH oxidase and chronic granulomatous disease.Phosphatidylinositol 3-kinase-dependent membrane recruitment of Rac-1 and p47phox is critical for alpha-platelet-derived growth factor receptor-induced production of reactive oxygen species.The NADPH oxidase complex of phagocytic leukocytes: a biochemical and cytochemical view.Antagonistic cross-talk between Rac and Cdc42 GTPases regulates generation of reactive oxygen species.The genetic basis of chronic granulomatous disease.Mutagenesis of an arginine- and lysine-rich domain in the gp91(phox) subunit of the phagocyte NADPH-oxidase flavocytochrome b558.Rac1, and not Rac2, is involved in the regulation of the intracellular hydrogen peroxide level in HepG2 cells.Activation of NADPH oxidase involves the dissociation of p21rac from its inhibitory GDP/GTP exchange protein (rhoGDI) followed by its translocation to the plasma membrane.Activation of the O2(-)-generating NADPH oxidase in a semi-recombinant cell-free system. Assessment of the function of Rac in the activation process.Modulation of RhoGTPases improves the behavioral phenotype and reverses astrocytic deficits in a mouse model of Rett syndrome.Mechanisms of NADPH oxidase activation in human neutrophils: p67phox is required for the translocation of rac 1 but not of rac 2 from cytosol to the membranes.Impairment of autoregulatory vasodilation by NAD(P)H oxidase-dependent superoxide generation during acute stage of subarachnoid hemorrhage in rat pial artery.Human monocytes use Rac1, not Rac2, in the NADPH oxidase complex.Liposomes comprising anionic but not neutral phospholipids cause dissociation of Rac(1 or 2) x RhoGDI complexes and support amphiphile-independent NADPH oxidase activation by such complexes.A role for hydroxy-methylglutaryl coenzyme a reductase in pulmonary inflammation and host defense.The renaturable 69- and 63-kDa protein kinases that undergo rapid activation in chemoattractant-stimulated guinea pig neutrophils are p21-activated kinases.Impaired NADPH oxidase activity in Rac2-deficient murine neutrophils does not result from defective translocation of p47phox and p67phox and can be rescued by exogenous arachidonic acid.Nitric oxide attenuates IGF-I-induced aortic smooth muscle cell motility by decreasing Rac1 activity: essential role of PTP-PEST and p130cas.
P2860
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P2860
Requirement for posttranslational processing of Rac GTP-binding proteins for activation of human neutrophil NADPH oxidase.
description
1993 nî lūn-bûn
@nan
1993 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի մարտին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Requirement for posttranslatio ...... uman neutrophil NADPH oxidase.
@ast
Requirement for posttranslatio ...... uman neutrophil NADPH oxidase.
@en
Requirement for posttranslatio ...... uman neutrophil NADPH oxidase.
@nl
type
label
Requirement for posttranslatio ...... uman neutrophil NADPH oxidase.
@ast
Requirement for posttranslatio ...... uman neutrophil NADPH oxidase.
@en
Requirement for posttranslatio ...... uman neutrophil NADPH oxidase.
@nl
prefLabel
Requirement for posttranslatio ...... uman neutrophil NADPH oxidase.
@ast
Requirement for posttranslatio ...... uman neutrophil NADPH oxidase.
@en
Requirement for posttranslatio ...... uman neutrophil NADPH oxidase.
@nl
P2093
P2860
P356
P1476
Requirement for posttranslatio ...... uman neutrophil NADPH oxidase.
@en
P2093
D J Uhlinger
G M Bokoch
J T Curnutte
P G Heyworth
P2860
P304
P356
10.1091/MBC.4.3.261
P577
1993-03-01T00:00:00Z