Posttranslational modification of the AU-rich element binding protein HuR by protein kinase Cdelta elicits angiotensin II-induced stabilization and nuclear export of cyclooxygenase 2 mRNA
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Posttranslational control of HuR functionFeedback Regulation of Kinase Signaling Pathways by AREs and GREsCytoskeleton-Dependent Transport as a Potential Target for Interfering with Post-transcriptional HuR mRNA RegulonsFunctional interplay between RNA-binding protein HuR and microRNAsMucosal injuries due to ribosome-inactivating stress and the compensatory responses of the intestinal epithelial barrierCurrent Evidence and Future Perspectives on HuR and Breast Cancer Development, Prognosis, and TreatmentPosttranscriptional regulation of cancer traits by HuRMultiple functions of the RNA-binding protein HuR in cancer progression, treatment responses and prognosisIntracellular localization and interaction of mRNA binding proteins as detected by FRET.Attenuation of the ELAV1-like protein HuR sensitizes adenocarcinoma cells to the intrinsic apoptotic pathway by increasing the translation of caspase-2L.RNA-binding proteins implicated in the hypoxic response.Tandem phosphorylation of serines 221 and 318 by protein kinase Cdelta coordinates mRNA binding and nucleocytoplasmic shuttling of HuR.Reduced nuclear export of HuR mRNA by HuR is linked to the loss of HuR in replicative senescence.RNPC1 modulates the RNA-binding activity of, and cooperates with, HuR to regulate p21 mRNA stability.T cell LFA-1 engagement induces HuR-dependent cytokine mRNA stabilization through a Vav-1, Rac1/2, p38MAPK and MKK3 signaling cascadeRNA binding protein CUGBP2/CELF2 mediates curcumin-induced mitotic catastrophe of pancreatic cancer cells.Altered VEGF mRNA stability following treatments with immunosuppressive agents: implications for cancer developmentHuR: a promising therapeutic target for angiogenesisRegulation of HuR by DNA Damage Response Kinases.Thy-1 mRNA destabilization by norepinephrine a 3' UTR cAMP responsive decay element and involves RNA binding proteins.Coordinated expression of tristetraprolin post-transcriptionally attenuates mitogenic induction of the oncogenic Ser/Thr kinase Pim-1.PKCα binds G3BP2 and regulates stress granule formation following cellular stressThe p38/MK2-driven exchange between tristetraprolin and HuR regulates AU-rich element-dependent translation.Global dissociation of HuR-mRNA complexes promotes cell survival after ionizing radiationStabilization of Dll1 mRNA by Elavl1/HuR in neuroepithelial cells undergoing mitosis.Loss of CARM1 is linked to reduced HuR function in replicative senescence.Post-Transcriptional Control of the Hypoxic Response by RNA-Binding Proteins and MicroRNAs.Regulation of cyclooxygenase-2 and cytosolic phospholipase A2 gene expression by lipopolysaccharide through the RNA-binding protein HuR: involvement of NADPH oxidase, reactive oxygen species and mitogen-activated protein kinasesThe RNA-binding protein HuR stabilizes cytosolic phospholipase A2α mRNA under interleukin-1β treatment in non-small cell lung cancer A549 CellsHuR mediates the synergistic effects of angiotensin II and IL-1β on vascular COX-2 expression and cell migration.5, 8, 11, 14-eicosatetraynoic acid suppresses CCL2/MCP-1 expression in IFN-γ-stimulated astrocytes by increasing MAPK phosphatase-1 mRNA stability.Downregulation of HuR as a new mechanism of doxorubicin resistance in breast cancer cells.Regulation of cytoplasmic mRNA decay.HuR function in disease.RNA-stabilizing proteins as molecular targets in cardiovascular pathologies.Two in-and-out modulation strategies for endoplasmic reticulum stress-linked gene expression of pro-apoptotic macrophage-inhibitory cytokine 1.Saturated fatty acids induce post-transcriptional regulation of HAMP mRNA via AU-rich element-binding protein, human antigen R (HuR).The C-terminal RNA binding motif of HuR is a multi-functional domain leading to HuR oligomerization and binding to U-rich RNA targets.Phosphoregulation of the RNA-binding protein Hu antigen R (HuR) by Cdk5 affects centrosome function.Functional coordination and HuR-mediated regulation of mRNA stability during T cell activation
P2860
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P2860
Posttranslational modification of the AU-rich element binding protein HuR by protein kinase Cdelta elicits angiotensin II-induced stabilization and nuclear export of cyclooxygenase 2 mRNA
description
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im April 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/04/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/04/01)
@nl
наукова стаття, опублікована у квітні 2008
@uk
مقالة علمية (نشرت في أبريل 2008)
@ar
name
Posttranslational modification ...... xport of cyclooxygenase 2 mRNA
@ast
Posttranslational modification ...... xport of cyclooxygenase 2 mRNA
@en
Posttranslational modification ...... xport of cyclooxygenase 2 mRNA
@nl
type
label
Posttranslational modification ...... xport of cyclooxygenase 2 mRNA
@ast
Posttranslational modification ...... xport of cyclooxygenase 2 mRNA
@en
Posttranslational modification ...... xport of cyclooxygenase 2 mRNA
@nl
prefLabel
Posttranslational modification ...... xport of cyclooxygenase 2 mRNA
@ast
Posttranslational modification ...... xport of cyclooxygenase 2 mRNA
@en
Posttranslational modification ...... xport of cyclooxygenase 2 mRNA
@nl
P2093
P2860
P3181
P356
P1476
Posttranslational modification ...... xport of cyclooxygenase 2 mRNA
@en
P2093
Andrea Huwiler
Anke Doller
El-Sayed Akool
Josef Pfeilschifter
Roswitha Müller
Wolfgang Eberhardt
P2860
P304
P3181
P356
10.1128/MCB.01530-07
P407
P577
2008-02-19T00:00:00Z