Phosphorylation of CARMA1 plays a critical role in T Cell receptor-mediated NF-kappaB activation
about
Ca2+/calmodulin-dependent protein kinase II is a modulator of CARMA1-mediated NF-kappaB activationMalt1 ubiquitination triggers NF-kappaB signaling upon T-cell activationPhosphorylation and ubiquitination of the IkappaB kinase complex by two distinct signaling pathwaysDephosphorylation of Carma1 by PP2A negatively regulates T-cell activationMolecular pathway profiling of T lymphocyte signal transduction pathways; Th1 and Th2 genomic fingerprints are defined by TCR and CD28-mediated signalingCutting edge: the "death" adaptor CRADD/RAIDD targets BCL10 and suppresses agonist-induced cytokine expression in T lymphocytesNEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kappaB activationT cell activationCARMA3/Bcl10/MALT1-dependent NF-kappaB activation mediates angiotensin II-responsive inflammatory signaling in nonimmune cellsThe paracaspase MALT1: biological function and potential for therapeutic inhibitionNF-κB, the first quarter-century: remarkable progress and outstanding questionsThe Novel PKCθ from Benchtop to ClinicPKCθ/β and CYLD are antagonistic partners in the NFκB and NFAT transactivation pathways in primary mouse CD3+ T lymphocytesStructural Insights into the Assembly of CARMA1 and BCL10Regulation of inflammatory and antiviral signaling by A20.TCR signaling to NF-κB and mTORC1: Expanding roles of the CARMA1 complexProtein kinase C-δ negatively regulates T cell receptor-induced NF-κB activation by inhibiting the assembly of CARMA1 signalosomeNegative Regulation of CARD11 Signaling and Lymphoma Cell Survival by the E3 Ubiquitin Ligase RNF181NF-kappaB and the immune responseDeciphering the pathway from the TCR to NF-kappaBCD28 stimulation triggers NF-kappaB activation through the CARMA1-PKCtheta-Grb2/Gads axisCard9 controls a non-TLR signalling pathway for innate anti-fungal immunityMAGUK-controlled ubiquitination of CARMA1 modulates lymphocyte NF-kappaB activity.The protein kinase C-responsive inhibitory domain of CARD11 functions in NF-kappaB activation to regulate the association of multiple signaling cofactors that differentially depend on Bcl10 and MALT1 for association.Compensatory IKKalpha activation of classical NF-kappaB signaling during IKKbeta inhibition identified by an RNA interference sensitization screen.Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery.NF-kappaB activation in T cells requires discrete control of IkappaB kinase alpha/beta (IKKalpha/beta) phosphorylation and IKKgamma ubiquitination by the ADAP adapter proteinOncogenic activation of NF-kappaB.CARMA1 regulation of regulatory T cell development involves modulation of interleukin-2 receptor signaling.CARMA1-mediated NF-kappaB and JNK activation in lymphocytes.Pathogenetic importance and therapeutic implications of NF-κB in lymphoid malignancies.TCR-induced, PKC-θ-mediated NF-κB activation is regulated by a caspase-8-caspase-9-caspase-3 cascade.An enigmatic tail of CD28 signaling.Antigen receptor signaling to NF-kappaB via CARMA1, BCL10, and MALT1.Molecular basis of lysophosphatidic acid-induced NF-κB activationOncogenic CARD11 mutations induce hyperactive signaling by disrupting autoinhibition by the PKC-responsive inhibitory domainPKCθ synergizes with TLR-dependent TRAF6 signaling pathway to upregulate MUC5AC mucin via CARMA1.MALT1 auto-proteolysis is essential for NF-κB-dependent gene transcription in activated lymphocytes.Thrombin-dependent NF-{kappa}B activation and monocyte/endothelial adhesion are mediated by the CARMA3·Bcl10·MALT1 signalosomeThe dynamic distribution of CARD11 at the immunological synapse is regulated by the inhibitory kinesin GAKIN.
P2860
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P2860
Phosphorylation of CARMA1 plays a critical role in T Cell receptor-mediated NF-kappaB activation
description
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im Dezember 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/12/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/12/01)
@nl
наукова стаття, опублікована в грудні 2005
@uk
مقالة علمية (نشرت في ديسمبر 2005)
@ar
name
Phosphorylation of CARMA1 play ...... -mediated NF-kappaB activation
@ast
Phosphorylation of CARMA1 play ...... -mediated NF-kappaB activation
@en
Phosphorylation of CARMA1 play ...... -mediated NF-kappaB activation
@nl
type
label
Phosphorylation of CARMA1 play ...... -mediated NF-kappaB activation
@ast
Phosphorylation of CARMA1 play ...... -mediated NF-kappaB activation
@en
Phosphorylation of CARMA1 play ...... -mediated NF-kappaB activation
@nl
prefLabel
Phosphorylation of CARMA1 play ...... -mediated NF-kappaB activation
@ast
Phosphorylation of CARMA1 play ...... -mediated NF-kappaB activation
@en
Phosphorylation of CARMA1 play ...... -mediated NF-kappaB activation
@nl
P2093
P921
P1433
P1476
Phosphorylation of CARMA1 play ...... -mediated NF-kappaB activation
@en
P2093
Bhanu Pappu
Demin Wang
Donghai Wang
Hongxiu Li
Masayuki Kobayashi
Reiko Matsumoto
Yuhong Chen
P304
P356
10.1016/J.IMMUNI.2005.10.007
P407
P577
2005-12-01T00:00:00Z