Human retinoic acid (RA) 4-hydroxylase (CYP26) is highly specific for all-trans-RA and can be induced through RA receptors in human breast and colon carcinoma cells
about
Metabolism and growth inhibition of four retinoids in head and neck squamous normal and malignant cellsStra6, a retinoic acid-responsive gene, participates in p53-induced apoptosis after DNA damage.Distinct populations of hepatic stellate cells in the mouse liver have different capacities for retinoid and lipid storage.Increased expression of the retinoic acid-metabolizing enzyme CYP26A1 during the progression of cervical squamous neoplasia and head and neck cancer.Phosphorylation by PKA potentiates retinoic acid receptor alpha activity by means of increasing interaction with and phosphorylation by cyclin H/cdk7.Substrate specificity and ligand interactions of CYP26A1, the human liver retinoic acid hydroxylase.Fenretinide metabolism in humans and mice: utilizing pharmacological modulation of its metabolic pathway to increase systemic exposureFirst chemical feature-based pharmacophore modeling of potent retinoidal retinoic acid metabolism blocking agents (RAMBAs): identification of novel RAMBA scaffolds.Targeting cytochrome P450 enzymes: a new approach in anti-cancer drug development.Role of pregnane X receptor in control of all-trans retinoic acid (ATRA) metabolism and its potential contribution to ATRA resistance.MS-275 synergistically enhances the growth inhibitory effects of RAMBA VN/66-1 in hormone-insensitive PC-3 prostate cancer cells and tumours.Pharmacokinetics and metabolism of 13-cis-retinoic acid (isotretinoin) in children with high-risk neuroblastoma - a study of the United Kingdom Children's Cancer Study Group.The retinoid anticancer signal: mechanisms of target gene regulation.Inhibition of all-TRANS-retinoic acid metabolism by R116010 induces antitumour activityBlocking the PAH2 domain of Sin3A inhibits tumorigenesis and confers retinoid sensitivity in triple negative breast cancerCombined staurosporine and retinoic acid induces differentiation in retinoic acid resistant acute promyelocytic leukemia cell lines.Vitamin A Inhibits Development of Dextran Sulfate Sodium-Induced Colitis and Colon Cancer in a Mouse Model.CYP26A1;B1 4-hydroxylate atRACytochrome p450 metabolism of betel quid-derived compounds: implications for the development of prevention strategies for oral and pharyngeal cancers.Retinoic acid-metabolizing enzyme cytochrome P450 26A1 promotes skin carcinogenesis induced by 7,12-dimethylbenz[a]anthracene.The anti-cancer effect of retinoic acid signaling in CRC occurs via decreased growth of ALDH+ colon cancer stem cells and increased differentiation of stem cellsAssociation study between novel CYP26 polymorphisms and the risk of betel quid-related malignant oral disorders
P2860
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P2860
Human retinoic acid (RA) 4-hydroxylase (CYP26) is highly specific for all-trans-RA and can be induced through RA receptors in human breast and colon carcinoma cells
description
1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1998
@ast
im August 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/08/01)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/08/01)
@nl
наукова стаття, опублікована в серпні 1998
@uk
مقالة علمية (نشرت في أغسطس 1998)
@ar
name
Human retinoic acid (RA) 4-hyd ...... east and colon carcinoma cells
@ast
Human retinoic acid (RA) 4-hyd ...... east and colon carcinoma cells
@en
Human retinoic acid (RA) 4-hyd ...... east and colon carcinoma cells
@nl
type
label
Human retinoic acid (RA) 4-hyd ...... east and colon carcinoma cells
@ast
Human retinoic acid (RA) 4-hyd ...... east and colon carcinoma cells
@en
Human retinoic acid (RA) 4-hyd ...... east and colon carcinoma cells
@nl
prefLabel
Human retinoic acid (RA) 4-hyd ...... east and colon carcinoma cells
@ast
Human retinoic acid (RA) 4-hyd ...... east and colon carcinoma cells
@en
Human retinoic acid (RA) 4-hyd ...... east and colon carcinoma cells
@nl
P2093
P3181
P1476
Human retinoic acid (RA) 4-hyd ...... east and colon carcinoma cells
@en
P2093
B M van der Leede
B van der Burg
C E van den Brink
E Sonneveld
M Petkovich
P T van der Saag
R K Schulkes
P304
P3181
P407
P577
1998-08-01T00:00:00Z