Inhibition of all-TRANS-retinoic acid metabolism by R116010 induces antitumour activity
about
Role of Retinoic Acid-Metabolizing Cytochrome P450s, CYP26, in Inflammation and CancerNovel retinoic acid metabolism blocking agents have potent inhibitory activities on human breast cancer cells and tumour growth.Therapeutic potential of the inhibition of the retinoic acid hydroxylases CYP26A1 and CYP26B1 by xenobiotics.Substrate specificity and ligand interactions of CYP26A1, the human liver retinoic acid hydroxylase.Retinoids in cancer therapy and chemoprevention: promise meets resistance.Cancer prevention and therapy: strategies and problems.First chemical feature-based pharmacophore modeling of potent retinoidal retinoic acid metabolism blocking agents (RAMBAs): identification of novel RAMBA scaffolds.Molecular aetiology and pathogenesis of basal cell carcinoma.Molecular targeting of retinoic acid metabolism in neuroblastoma: the role of the CYP26 inhibitor R116010 in vitro and in vivo.Inhibitory effects of retinoic acid metabolism blocking agents (RAMBAs) on the growth of human prostate cancer cells and LNCaP prostate tumour xenografts in SCID mice.Cytochrome P450s in the regulation of cellular retinoic acid metabolismThe role of CYP26 enzymes in retinoic acid clearance.Molecular aspects of azoles-induced teratogenesis.Improved Homology Model of the Human all-trans Retinoic Acid Metabolizing Enzyme CYP26A1.A novel role for the retinoic acid-catabolizing enzyme CYP26A1 in Barrett's associated adenocarcinoma.Increasing the intracellular availability of all-trans retinoic acid in neuroblastoma cellsTranscription factor TLX1 controls retinoic acid signaling to ensure spleen development.13cRA regulates the differentiation of antler chondrocytes through targeting Runx3.Convenient and Reliable Routes Towards 2-Aminothiazoles: Palladium-CatalyzedversusCopper-Catalyzed Aminations of HalothiazolesImidazoles as potential anticancer agents
P2860
Q26800202-CF234095-BFA4-4E29-BC81-7FCE9E44233CQ30438632-5C3AACB3-3EF6-47ED-A22A-065C02BBA1A5Q34345596-12A1FAC5-E28E-4FEB-B3CC-2109492BDC17Q35122815-F6562AC4-3E04-4CBF-B327-F9A0158BCE97Q35567239-8E999678-6918-4F90-8EED-7172EFBA8290Q35594641-31A95463-4505-4FF3-80C4-40075AA86C3DQ35675265-B58BA043-C8B4-4E43-B14B-088B4EBA08D8Q36158929-258830ED-3EFE-4E3E-8476-0985B61CA44BQ36609453-D52F6724-0700-43CE-940C-4DB8FEABBEAAQ36613829-3C2C8131-9C16-4ABE-985C-E1618BDFA978Q37212128-F1D51760-522B-404F-8824-C1090FBA51CEQ37313897-5453EA21-6CBE-44E8-A5BB-46CB720743DBQ37681552-564DE163-C0A2-4F8E-8CE9-DD3853D5B805Q39902041-A8B7BE30-AE5B-4F4F-A801-95805424A5C6Q40039766-9D5B3260-6CE8-49C6-8957-C0B202EFA99FQ40457642-2D521F34-5217-4F92-AC06-08E4519343DCQ40663410-03DBEAC4-B1DD-4D84-9DA2-104D5AD1D905Q51206203-50FF9525-A984-476E-A13F-3B13F6E2203CQ58878126-7BC355AC-176F-4F78-8AE1-F8C01613D498Q59149996-6179C21F-F975-4F72-83A3-607C3DAD82EC
P2860
Inhibition of all-TRANS-retinoic acid metabolism by R116010 induces antitumour activity
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Inhibition of all-TRANS-retinoic acid metabolism by R116010 induces antitumour activity
@ast
Inhibition of all-TRANS-retinoic acid metabolism by R116010 induces antitumour activity
@en
type
label
Inhibition of all-TRANS-retinoic acid metabolism by R116010 induces antitumour activity
@ast
Inhibition of all-TRANS-retinoic acid metabolism by R116010 induces antitumour activity
@en
prefLabel
Inhibition of all-TRANS-retinoic acid metabolism by R116010 induces antitumour activity
@ast
Inhibition of all-TRANS-retinoic acid metabolism by R116010 induces antitumour activity
@en
P2093
P2860
P356
P1476
Inhibition of all-TRANS-retinoic acid metabolism by R116010 induces antitumour activity
@en
P2093
B J van der Leede
C Van Hove
G Willemsens
H Bruwiere
J Van Heusden
P2860
P2888
P304
P356
10.1038/SJ.BJC.6600056
P407
P577
2002-02-01T00:00:00Z