The cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice
about
Gene therapy for carcinoma of the breast: Pro-apoptotic gene therapyStem cells as cellular vehicles for gene therapy against glioblastomaMolecular characterization of prostate carcinoma tumor antigen-1, PCTA-1, a human galectin-8 related geneThe T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 receptor 2 chainsPEG-3, a nontransforming cancer progression gene, is a positive regulator of cancer aggressiveness and angiogenesisTargeting a newly established spontaneous feline fibrosarcoma cell line by gene transferIdentification and temporal expression pattern of genes modulated during irreversible growth arrest and terminal differentiation in human melanoma cells.Identification and cloning of human polynucleotide phosphorylase, hPNPase old-35, in the context of terminal differentiation and cellular senescence.RaSH, a rapid subtraction hybridization approach for identifying and cloning differentially expressed genes.Recombinant interleukin-24 lacks apoptosis-inducing properties in melanoma cells.Cisplatin enhances protein kinase R-like endoplasmic reticulum kinase- and CD95-dependent melanoma differentiation-associated gene-7/interleukin-24-induced killing in ovarian carcinoma cellsEradication of therapy-resistant human prostate tumors using an ultrasound-guided site-specific cancer terminator virus delivery approach.Targeting gene expression selectively in cancer cells by using the progression-elevated gene-3 promoter.MDA-7/IL-24-induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK-dependent mechanism.Inhibition of multiple protective signaling pathways and Ad.5/3 delivery enhances mda-7/IL-24 therapy of malignant gliomaPERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells.The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosisCombinatorial effect of non-steroidal anti-inflammatory drugs and NF-κB inhibitors in ovarian cancer therapy.Characterization of the canine mda-7 gene, transcripts and expression patterns.Dual cancer-specific targeting strategy cures primary and distant breast carcinomas in nude mice.mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK.Tumour suppressor function of MDA-7/IL-24 in human breast cancerEnhanced apoptosis-inducing function of MDA-7/IL-24 RGD mutant via the increased adhesion to tumor cells.MicroRNA-205-directed transcriptional activation of tumor suppressor genes in prostate cancer.Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions.The development of MDA-7/IL-24 as a cancer therapeuticSecretable chaperone Grp170 enhances therapeutic activity of a novel tumor suppressor, mda-7/IL-24IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesisEnhancing mda-7/IL-24 therapy in renal carcinoma cells by inhibiting multiple protective signaling pathways using sorafenib and by Ad.5/3 gene deliveryA serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels.Interleukin-24 is correlated with differentiation and lymph node numbers in rectal cancer.Insights into glutamate transport regulation in human astrocytes: cloning of the promoter for excitatory amino acid transporter 2 (EAAT2).RGS16, a novel p53 and pRb cross-talk candidate inhibits migration and invasion of pancreatic cancer cells.Reversing translational suppression and induction of toxicity in pancreatic cancer cells using a chemoprevention gene therapy approachTargeting breast cancer-initiating/stem cells with melanoma differentiation-associated gene-7/interleukin-24.Gene Therapies for Cancer: Strategies, Challenges and Successes.mda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity.Splice variants of mda-7/IL-24 differentially affect survival and induce apoptosis in U2OS cells.Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cellsmda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine
P2860
Q24797919-56715582-B245-400C-B956-A7E2CBDC28DAQ26771835-62CA79B4-BC45-4386-916F-BEAD514A5CF1Q28138269-6A70204A-D079-4477-8E7F-4248F6700C89Q28265025-04C1CD27-1281-4327-8106-87CC8083BA09Q28571724-74F9B809-7DA1-4FED-BFB6-D696652D52FAQ28729067-CFFAD400-5209-42F7-957E-1398CA4A2950Q30641951-66E5565F-C12C-4901-A28E-72064C9F0D79Q30873494-A385944C-8292-4E0F-90D6-50B3880C702DQ30953741-D97ED952-88F3-4CB4-903F-5840A2DCE4D7Q33309944-83E110D1-60C8-41A3-A54B-7F376E6B3972Q33613377-24E79888-32E1-4C17-A670-26747846F9A3Q33730689-D2D7BFF5-8356-45FC-985C-714F1E93ACA4Q33762359-C4606CC2-7705-4D4E-AE10-D7D3247E8C99Q33926871-F8E69FCB-1CFA-4B18-924A-5D27295045AEQ33930115-DB769559-3667-442A-895C-AE7018F91D2BQ33931451-8438E439-07CE-4DF7-8255-36CFD161B5ACQ33992032-05741453-6CAC-41B9-8826-3083970B5A75Q34023344-F257441D-1EFD-4CD4-85DE-8827FE7A58DDQ34040220-C060C0E2-C37C-412D-A43A-5AEAAE3661DEQ34048220-B251C759-7C21-4A3A-8377-82238B4FD9E8Q34098956-B41F33D8-A422-4FFD-B7CA-40DA04CCA54BQ34114046-875F5843-6E13-4BE6-A215-AA36DA6CD9CCQ34128541-683A3ACC-DC1C-4AC1-B5A4-ADE53561EF2EQ34133056-DB195335-6CD6-4772-B3CE-D32101D52B4FQ34152063-3F69C6AA-04DB-45C7-A460-201FE788ABF5Q34163896-4D9458EB-FDCB-4B1F-A98C-C9A1FF687C44Q34514012-1AE5BB4E-6D8C-4E3C-8481-6F0F303B41E4Q34577866-B02B06CB-AA87-4A94-BC5B-C50E6D03C1D2Q34616542-0EF79E14-18A2-49FA-9F4E-A3FECF2FB8E6Q34701049-AC626911-A127-4BDA-B0D7-DE377B16BCBEQ34717408-25A9D0A8-A23F-462C-A5E6-492FA17AE22AQ34762681-B4C62506-8F5E-40C6-9642-F2A02228CEDEQ34786650-24BF2CFB-2A93-4B39-AF3A-196AC84B00E9Q34946787-4CFD3077-9402-409A-8E87-FB7488714B9BQ35101122-745D57AD-DA88-429C-9089-07D9371A35FFQ35186312-F95855F1-0AED-4C75-AEE8-E0BC0E1CB9E3Q35189796-E0E47117-4BCC-40F6-9FB0-1C1F8B5A1165Q35256043-4B39A05C-376D-4009-8C8D-DBD48FEB2473Q35587169-1F90E569-6195-4857-888B-756F91035630Q35609031-88968945-1EC6-41B7-8892-ED88EDB86460
P2860
The cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice
description
1998 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 1998
@ast
im November 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/11/24)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/11/24)
@nl
наукова стаття, опублікована в листопаді 1998
@uk
name
The cancer growth suppressor g ...... bits tumor growth in nude mice
@ast
The cancer growth suppressor g ...... bits tumor growth in nude mice
@en
The cancer growth suppressor g ...... bits tumor growth in nude mice
@nl
type
label
The cancer growth suppressor g ...... bits tumor growth in nude mice
@ast
The cancer growth suppressor g ...... bits tumor growth in nude mice
@en
The cancer growth suppressor g ...... bits tumor growth in nude mice
@nl
prefLabel
The cancer growth suppressor g ...... bits tumor growth in nude mice
@ast
The cancer growth suppressor g ...... bits tumor growth in nude mice
@en
The cancer growth suppressor g ...... bits tumor growth in nude mice
@nl
P2093
P2860
P356
P1476
The cancer growth suppressor g ...... bits tumor growth in nude mice
@en
P2093
C. S. Young
J. C. Reed
M. T. Madireddi
N. I. Goldstein
P. B. Fisher
P2860
P304
14400–14405
P356
10.1073/PNAS.95.24.14400
P407
P577
1998-11-24T00:00:00Z