Secretable chaperone Grp170 enhances therapeutic activity of a novel tumor suppressor, mda-7/IL-24 - Wikidata - awgldk - TriplyDB

Secretable chaperone Grp170 enhances therapeutic activity of a novel tumor suppressor, mda-7/IL-24

Secretable chaperone Grp170 enhances therapeutic activity of a novel tumor suppressor, mda-7/IL-24

http://www.wikidata.org/entity/Q34514012

about

Extracellular HSPs: The Complicated Roles of Extracellular HSPs in Immunity Unfolding the Role of Large Heat Shock Proteins: New Insights and Therapeutic Implications BiP and its nucleotide exchange factors Grp170 and Sil1: mechanisms of action and biological functions High molecular weight stress proteins: Identification, cloning and utilisation in cancer immunotherapy The Endoplasmic Reticulum Chaperone GRP170: From Immunobiology to Cancer Therapeutics Developing an effective gene therapy for prostate cancer: New technologies with potential to translate from the laboratory into the clinic Eradication of therapy-resistant human prostate tumors using an ultrasound-guided site-specific cancer terminator virus delivery approach.Mechanism of autophagy to apoptosis switch triggered in prostate cancer cells by antitumor cytokine melanoma differentiation-associated gene 7/interleukin-24 Adoptive cell therapy of prostate cancer using female mice-derived T cells that react with prostate antigens.Gene Therapies for Cancer: Strategies, Challenges and Successes.mda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity.CD204 suppresses large heat shock protein-facilitated priming of tumor antigen gp100-specific T cells and chaperone vaccine activity against mouse melanoma.Mechanism by which Mcl-1 regulates cancer-specific apoptosis triggered by mda-7/IL-24, an IL-10-related cytokine mda-7/IL-24 differentially regulates soluble and nuclear clusterin in prostate cancer.MDA-7/IL-24: multifunctional cancer killing cytokine Activation of the MDA-5-IPS-1 Viral Sensing Pathway Induces Cancer Cell Death and Type I IFN-Dependent Antitumor Immunity.Selected approaches for rational drug design and high throughput screening to identify anti-cancer molecules TAT-IL-24-KDEL-induced apoptosis is inhibited by survivin but restored by the small molecular survivin inhibitor, YM155, in cancer cells.Secretion of stress protein grp170 promotes immune-mediated inhibition of murine prostate tumor.Novel mechanism of MDA-7/IL-24 cancer-specific apoptosis through SARI induction.A novel nanoparticle containing neuritin peptide with grp170 induces a CTL response to inhibit tumor growth.Cell-penetrating and endoplasmic reticulum-locating TAT-IL-24-KDEL fusion protein induces tumor apoptosis.A multifunctional chimeric chaperone serves as a novel immune modulator inducing therapeutic antitumor immunity.Engineering Grp170-based immune modulators for cancer immunotherapy.The potential of virus-based gene therapies for treatment of metastatic kidney cancer.Iron-induced calcification in human aortic vascular smooth muscle cells through interleukin-24 (IL-24), with/without TNF-alpha.Soluble expression, rapid purification, and characterization of human interleukin-24 (IL-24) using a MBP-SUMO dual fusion system in Escherichia coli.

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Secretable chaperone Grp170 enhances therapeutic activity of a novel tumor suppressor, mda-7/IL-24

http://www.wikidata.org/entity/Q34514012

description

2008 nî lūn-bûn

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2008 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2008 թվականի մայիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Secretable chaperone Grp170 en ...... tumor suppressor, mda-7/IL-24

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Secretable chaperone Grp170 en ...... tumor suppressor, mda-7/IL-24

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Secretable chaperone Grp170 en ...... tumor suppressor, mda-7/IL-24

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type

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Secretable chaperone Grp170 en ...... tumor suppressor, mda-7/IL-24

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Secretable chaperone Grp170 en ...... tumor suppressor, mda-7/IL-24

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Secretable chaperone Grp170 en ...... tumor suppressor, mda-7/IL-24

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Secretable chaperone Grp170 en ...... tumor suppressor, mda-7/IL-24

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Secretable chaperone Grp170 en ...... tumor suppressor, mda-7/IL-24

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Secretable chaperone Grp170 en ...... tumor suppressor, mda-7/IL-24

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0008-5472.CAN-08-0156

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Cancer Research

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Secretable chaperone Grp170 en ...... tumor suppressor, mda-7/IL-24

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P2093

Barbara A Foster

http://www.w3.org/2001/XMLSchema#string

John Subjeck

http://www.w3.org/2001/XMLSchema#string

Paul B Fisher

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Ping Gao

http://www.w3.org/2001/XMLSchema#string

Xiang-Yang Wang

http://www.w3.org/2001/XMLSchema#string

Xiaolei Sun

http://www.w3.org/2001/XMLSchema#string

Xing Chen

http://www.w3.org/2001/XMLSchema#string

Yanping Wang

http://www.w3.org/2001/XMLSchema#string

P2860

The induction of tolerance by dendritic cells that have captured apoptotic cells

The cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice

mda-7/IL-24, a novel cancer selective apoptosis inducing cytokine gene: from the laboratory into the clinic

Cutting edge: FISP (IL-4-induced secreted protein), a novel cytokine-like molecule secreted by Th2 cells

Novel heat shock protein Hsp70L1 activates dendritic cells and acts as a Th1 polarizing adjuvant.

Corpse clearance defines the meaning of cell death.

mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK.

Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression.

Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression.

Molecular characterization of defective antigen processing in human prostate cancer.

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3890-3898

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10.1158/0008-5472.CAN-08-0156

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10

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68

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18483274

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molecular chaperones

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3025602

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