Expression patterns of the multiple transcripts from the folylpolyglutamate synthetase gene in human leukemias and normal differentiated tissues
about
Analysis of folylpoly-gamma-glutamate synthetase gene expression in human B-precursor ALL and T-lineage ALL cellsThe human reduced folate carrier gene is ubiquitously and differentially expressed in normal human tissues: identification of seven non-coding exons and characterization of a novel promoterHumanizing mouse folate metabolism: conversion of the dual-promoter mouse folylpolyglutamate synthetase gene to the human single-promoter structure.Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance.The human reduced folate carrier gene is regulated by the AP2 and sp1 transcription factor families and a functional 61-base pair polymorphism.Out-of-frame start codons prevent translation of truncated nucleo-cytosolic cathepsin L in vivo.Shaping of tumor and drug-resistant genomes by instability and selection.Structure and regulation of the murine reduced folate carrier gene: identification of four noncoding exons and promoters and regulation by dietary folates.
P2860
Q21260431-0A904530-5C91-460F-A128-278E7CD81649Q24534785-803F33C8-B75D-44A7-B177-AEFEE0CC77EFQ37702952-E5D680AA-DEE2-447F-B7A6-9AD17E892515Q38821227-D2B727B6-498B-4D29-AEF5-95383421F0BEQ40704467-F132F0C4-DC24-4DC3-A49F-6CE4140CDC1AQ42682011-B283CF87-75F0-497E-9EC2-7EA0B6FAF4BCQ44508745-A93B7968-A2AC-482E-BED7-8C4F65067440Q45173708-AE0513E2-A77F-4093-81B1-ED4F566FFFA1
P2860
Expression patterns of the multiple transcripts from the folylpolyglutamate synthetase gene in human leukemias and normal differentiated tissues
description
2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2000
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im November 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/11/17)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/11/17)
@nl
наукова стаття, опублікована в листопаді 2000
@uk
name
Expression patterns of the mul ...... normal differentiated tissues
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Expression patterns of the mul ...... normal differentiated tissues
@en
Expression patterns of the mul ...... normal differentiated tissues
@nl
type
label
Expression patterns of the mul ...... normal differentiated tissues
@ast
Expression patterns of the mul ...... normal differentiated tissues
@en
Expression patterns of the mul ...... normal differentiated tissues
@nl
prefLabel
Expression patterns of the mul ...... normal differentiated tissues
@ast
Expression patterns of the mul ...... normal differentiated tissues
@en
Expression patterns of the mul ...... normal differentiated tissues
@nl
P2093
P2860
P356
P1476
Expression patterns of the mul ...... normal differentiated tissues
@en
P2093
F. B. Turner
R. G. Moran
S. M. Taylor
P2860
P304
35960–35968
P356
10.1074/JBC.M005228200
P407
P577
2000-11-17T00:00:00Z