Huntingtin functions as a scaffold for selective macroautophagy
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Advances in Autophagy Regulatory MechanismsThe Function of Autophagy in Neurodegenerative DiseasesTherapeutic targeting of autophagy in neurodegenerative and infectious diseasesDrosophila as an In Vivo Model for Human Neurodegenerative DiseaseGeneration and Characterization of Knock-in Mouse Models Expressing Versions of Huntingtin with Either an N17 or a Combined PolyQ and Proline-Rich Region Deletion.Is Huntingtin Dispensable in the Adult Brain?N-terminal Huntingtin Knock-In Mice: Implications of Removing the N-terminal Region of Huntingtin for Therapy.AUTEN-67 (Autophagy Enhancer-67) Hampers the Progression of Neurodegenerative Symptoms in a Drosophila model of Huntington's Disease.Assessing Basal and Acute Autophagic Responses in the Adult Drosophila Nervous System: The Impact of Gender, Genetics and Diet on Endogenous Pathway ProfilesBlocking the association of HDAC4 with MAP1S accelerates autophagy clearance of mutant Huntingtin.The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms.Autophagy and primary cilia: dual interplayStructure and function of the ULK1 complex in autophagyMechanisms of Selective Autophagy in Normal Physiology and CancerThe Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB PerspectiveVCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease.ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington's disease models.Oxidative Stress and Huntington's Disease: The Good, The Bad, and The Ugly.Autophagy and Microglia: Novel Partners in Neurodegeneration and Aging.Active Interaction Mapping Reveals the Hierarchical Organization of Autophagy.Primary cilia and autophagic dysfunction in Huntington's disease.Studying polyglutamine diseases in Drosophila.Breaking fat: The regulation and mechanisms of lipophagy.Autophagy in Dictyostelium: Mechanisms, regulation and disease in a simple biomedical model.The Role of Cathepsin D in the Pathogenesis of Human Neurodegenerative Disorders.Polyglutamine tracts regulate beclin 1-dependent autophagy.Hereditary chorea - what else to consider when the Huntington's disease genetics test is negative?The BEACH-containing protein WDR81 coordinates p62 and LC3C to promote aggrephagy.Mechanistic insights into selective autophagy pathways: lessons from yeast.Autophagy in adhesion and migration.Huntingtin polyQ Mutation Impairs the 17β-Estradiol/Neuroglobin Pathway Devoted to Neuron Survival.Mechanisms of Autophagy Initiation.Autophagy and Human Neurodegenerative Diseases-A Fly's Perspective.Characterization of axonal transport defects in Drosophila Huntingtin mutants.Proteostasis of Huntingtin in Health and DiseaseAmpk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy.Receptor-Bound Targets of Selective Autophagy Use a Scaffold Protein to Activate the Atg1 Kinase.A seeding based cellular assay of tauopathy.Control of the structural landscape and neuronal proteotoxicity of mutant Huntingtin by domains flanking the polyQ tract.Selective role of autophagy in neuronal function and neurodegenerative diseases.
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P2860
Huntingtin functions as a scaffold for selective macroautophagy
description
2015 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2015
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im März 2015 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2015/03/01)
@sk
vědecký článek publikovaný v roce 2015
@cs
wetenschappelijk artikel (gepubliceerd op 2015/03/01)
@nl
наукова стаття, опублікована в березні 2015
@uk
مقالة علمية (نشرت في مارس 2015)
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name
Huntingtin functions as a scaffold for selective macroautophagy
@ast
Huntingtin functions as a scaffold for selective macroautophagy
@en
Huntingtin functions as a scaffold for selective macroautophagy
@nl
type
label
Huntingtin functions as a scaffold for selective macroautophagy
@ast
Huntingtin functions as a scaffold for selective macroautophagy
@en
Huntingtin functions as a scaffold for selective macroautophagy
@nl
prefLabel
Huntingtin functions as a scaffold for selective macroautophagy
@ast
Huntingtin functions as a scaffold for selective macroautophagy
@en
Huntingtin functions as a scaffold for selective macroautophagy
@nl
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Huntingtin functions as a scaffold for selective macroautophagy
@en
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Antonio Tito
Bindi Patel
Dongsheng Chen
Erin F Stimming
Gabriela David
Sheng Zhang
Zhihua Chen
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P2888
P304
P3181
P356
10.1038/NCB3101
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2015-02-16T00:00:00Z
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P6179
1012550836