Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis - Wikidata - awgldk - TriplyDB

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

http://www.wikidata.org/entity/Q28131672

about

Genetic counseling for FTD/ALS caused by the C9ORF72 hexanucleotide expansion Progranulin in frontotemporal lobar degeneration and neuroinflammation Dysregulation of the autophagy-endolysosomal system in amyotrophic lateral sclerosis and related motor neuron diseases Widespread structural and functional connectivity changes in amyotrophic lateral sclerosis: insights from advanced neuroimaging research Military service, deployments, and exposures in relation to amyotrophic lateral sclerosis etiology and survival Phosphorylation of microtubule-associated protein tau by AMPK-related kinases Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis Redox signalling directly regulates TDP-43 via cysteine oxidation and disulphide cross-linking Molecular mechanism of oxidation-induced TDP-43 RRM1 aggregation and loss of function The FTLD risk factor TMEM106B and MAP6 control dendritic trafficking of lysosomes TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expression Biochemical and genetic evidence for a role of IGHMBP2 in the translational machinery TDP-35 sequesters TDP-43 into cytoplasmic inclusions through binding with RNA TARDBP mutation analysis in TDP-43 proteinopathies and deciphering the toxicity of mutant TDP-43 Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study Altered ribostasis: RNA-protein granules in degenerative disorders Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis C9ORF72, the new gene on the block, causes C9FTD/ALS: new insights provided by neuropathology Unconventional translation of C9ORF72 GGGGCC expansion generates insoluble polypeptides specific to c9FTD/ALS Recent progress in the discovery of small molecules for the treatment of amyotrophic lateral sclerosis (ALS)The genetics and neuropathology of frontotemporal lobar degeneration Whole-genome sequencing reveals a coding non-pathogenic variant tagging a non-coding pathogenic hexanucleotide repeat expansion in C9orf72 as cause of amyotrophic lateral sclerosis Nuclear transport, oxidative stress, and neurodegeneration Eukaryotic stress granules are cleared by autophagy and Cdc48/VCP function ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import A harmonized classification system for FTLD-TDP pathology Exome sequencing reveals VCP mutations as a cause of familial ALS A seeding reaction recapitulates intracellular formation of Sarkosyl-insoluble transactivation response element (TAR) DNA-binding protein-43 inclusions Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD The pathobiology of splicing Conjoint pathologic cascades mediated by ALS/FTLD-U linked RNA-binding proteins TDP-43 and FUS Accumulation of transactive response DNA binding protein 43 in mild cognitive impairment and Alzheimer disease Sarcoplasmic redistribution of nuclear TDP-43 in inclusion body myositis Structural insights into TDP-43 in nucleic-acid binding and domain interactions A new subtype of frontotemporal lobar degeneration with FUS pathology Rapamycin rescues TDP-43 mislocalization and the associated low molecular mass neurofilament instability TDP-43 overexpression enhances exon 7 inclusion during the survival of motor neuron pre-mRNA splicing

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Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

http://www.wikidata.org/entity/Q28131672

description

2006 nî lūn-bûn

@nan

2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

Ubiquitinated TDP-43 in fronto ...... amyotrophic lateral sclerosis

@ast

Ubiquitinated TDP-43 in fronto ...... amyotrophic lateral sclerosis

@en

Ubiquitinated TDP-43 in fronto ...... amyotrophic lateral sclerosis

@nl

type

label

Ubiquitinated TDP-43 in fronto ...... amyotrophic lateral sclerosis

@ast

Ubiquitinated TDP-43 in fronto ...... amyotrophic lateral sclerosis

@en

Ubiquitinated TDP-43 in fronto ...... amyotrophic lateral sclerosis

@nl

prefLabel

Ubiquitinated TDP-43 in fronto ...... amyotrophic lateral sclerosis

@ast

Ubiquitinated TDP-43 in fronto ...... amyotrophic lateral sclerosis

@en

Ubiquitinated TDP-43 in fronto ...... amyotrophic lateral sclerosis

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SCIENCE.1134108

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Ubiquitinated TDP-43 in fronto ...... amyotrophic lateral sclerosis

@en

P2093

Adam C Truax

http://www.w3.org/2001/XMLSchema#string

Christopher M Clark

http://www.w3.org/2001/XMLSchema#string

Deepak M Sampathu

http://www.w3.org/2001/XMLSchema#string

Hans A Kretzschmar

http://www.w3.org/2001/XMLSchema#string

Ian R Mackenzie

http://www.w3.org/2001/XMLSchema#string

Jennifer Bruce

http://www.w3.org/2001/XMLSchema#string

Leo F McCluskey

http://www.w3.org/2001/XMLSchema#string

Linda K Kwong

http://www.w3.org/2001/XMLSchema#string

Matthew C Micsenyi

http://www.w3.org/2001/XMLSchema#string

Theresa Schuck

http://www.w3.org/2001/XMLSchema#string

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130-3

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scholarly article

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39057

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10.1126/SCIENCE.1134108

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5796

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314

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Eliezer Masliah

Bruce L. Miller

John Q. Trojanowski

Murray Grossman

Manuela Neumann

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2006-10-06T00:00:00Z

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6770719

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17023659

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amyotrophic lateral sclerosis

protein ubiquitination